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RTW Investments, LP

Activist investor & 5%+ owner · SC 13D/13G filings

Total Filings

219

Stocks Covered

89

Latest Filing

Nov 14, 2025

Filings

Axsome Therapeutics, Inc.

SC 13G/A · Feb 14, 2024

9.5%

4.5M shares

PTC Therapeutics, Inc.

SC 13G/A · Feb 14, 2024

9.8%

7.4M shares

Exagen Inc.

SC 13G/A · Feb 14, 2024

8.8%

1.5M shares

Mirati Therapeutics, Inc.

SC 13G/A · Feb 14, 2024

0.0%

0 shares

Avadel Pharmaceuticals PLC

SC 13G/A · Feb 14, 2024

10.0%

9.2M shares

Milestone Pharmaceuticals Inc.

SC 13G/A · Feb 14, 2024

10.0%

3.4M shares

89bio, Inc.

SC 13G · Feb 14, 2024

6.0%

5.6M shares

Sage Therapeutics, Inc.

SC 13G · Feb 14, 2024

8.7%

5.2M shares

Taysha Gene Therapies, Inc.

SC 13G · Feb 14, 2024

9.8%

18.5M shares

Acadia Pharmaceuticals Inc.

SC 13G · Feb 14, 2024

6.9%

11.3M shares

UroGen Pharma

SC 13G · Feb 14, 2024

5.6%

1.7M shares

Akero Therapeutics, Inc.

SC 13G · Feb 14, 2024

6.4%

3.6M shares

Arvinas, Inc.

SC 13G · Feb 14, 2024

6.2%

4.2M shares

N/A

ESSA Pharma Inc.

SC 13G · Feb 14, 2024

5.2%

2.3M shares

GH Research PLC

SC 13G · Feb 14, 2024

6.4%

3.3M shares

Pharming Group N.V.

SC 13G · Feb 14, 2024

5.8%

38.5M shares

Spyre Therapeutics, Inc.

SC 13G · Feb 14, 2024

6.2%

2.2M shares

SAB Biotherapeutics, Inc.

SC 13G · Feb 14, 2024

10.0%

9.2M shares

Avidity Biosciences, Inc.

SC 13D/A · Jan 24, 2024

58.4%

6.7M shares

CUTERA INC.

SC 13G · Jan 19, 2024

9.1%

1.8M shares

DermTech, Inc.

SC 13D/A · Dec 12, 2023

50.0%

0 shares

CARGO Therapeutics, Inc.

SC 13G · Nov 24, 2023

13.4%

5.2M shares

Rocket Pharmaceuticals, Inc.

SC 13D/A · Sep 19, 2023

520.2%

18.2M shares

N/A

ALLURION TECHNOLOGIES HOLDINGS, INC.

SC 13D · Aug 11, 2023

7.4%

3.5M shares

CUTERA INC.

SC 13D/A · May 10, 2023

9.3%

1.8M shares

Orchestra Biomed Holdings, Inc.

SC 13D/A · May 5, 2023

15.7%

5.6M shares

CUTERA INC.

SC 13D · Apr 13, 2023

9.3%

1.8M shares

Renovacor, Inc.

SC 13D/A · Apr 5, 2023

50.0%

0 shares

Rocket Pharmaceuticals, Inc.

SC 13D/A · Apr 5, 2023

522.9%

18.2M shares

Clearside Biomedical, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Athira Pharma, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

ASLAN Pharmaceuticals Limited

SC 13G/A · Feb 14, 2023

0.0%

0 shares

CytomX Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Adverum Biotechnologies, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

BELLUS Health Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Aptevo Therapeutics Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

ProQR Therapeutics N.V.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Macrogenics, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Vericel Corporation

SC 13G/A · Feb 14, 2023

6.6%

3.1M shares

IDEAYA Biosciences, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

N/A

Ultragenyx Pharmaceutical Inc.

SC 13G · Feb 14, 2023

5.7%

4.0M shares

TELA Bio, Inc.

SC 13G/A · Feb 14, 2023

2.0%

390K shares

Relmada Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

6.9%

2.1M shares

Mirati Therapeutics, Inc.

SC 13G · Feb 14, 2023

6.3%

3.6M shares

Tarsus Pharmaceuticals, Inc.

SC 13G/A · Feb 14, 2023

9.6%

2.5M shares

Celldex Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

6.5%

3.1M shares

Stoke Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

9.8%

3.9M shares

C4 Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

5.8%

2.8M shares

iTeos Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

PMV Pharmaceuticals, Inc.

SC 13G/A · Feb 14, 2023

9.5%

4.4M shares