MIST

Milestone Pharmaceuticals Inc.

Pharmaceutical PreparationsNasdaqNon-accelerated filer<br>Smaller reporting company

Total Trades

25

Buys

7

Sells

7

Largest Trade

N/A

Insiders

11

Institutional Funds

54

Inst. Value

$1M+

Activist Filings

32

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Bharucha DavidChief Medical Offi…GRANTN/A100KJan 28, 2026
Bharucha DavidChief Medical Offi…EXERCISEN/A20KJan 28, 2026
Bharucha DavidChief Medical Offi…SELL$100K–$500K70K$2.25Jan 28, 2026
Nelson Jeffrey EdwardCOOEXERCISEN/A20KJan 28, 2026
Nelson Jeffrey EdwardCOOSELL$100K–$500K70K$2.25Jan 28, 2026
Nelson Jeffrey EdwardCOOGRANTN/A100KJan 28, 2026
Muller LorenzChief Commercial O…EXERCISEN/A20KJan 28, 2026
Muller LorenzChief Commercial O…GRANTN/A100KJan 28, 2026
Muller LorenzChief Commercial O…SELL$100K–$500K65K$2.25Jan 28, 2026
Hasija AmitCFO & EVP of Corp.…GRANTN/A100KJan 28, 2026
Hasija AmitCFO & EVP of Corp.…SELL$100K–$500K70K$2.25Jan 28, 2026
Hasija AmitCFO & EVP of Corp.…EXERCISEN/A20KJan 28, 2026
Oliveto JosephPresident and CEOGRANTN/A280KJan 28, 2026
Oliveto JosephPresident and CEOSELL$100K–$500K168K$2.24Jan 28, 2026
Oliveto JosephPresident and CEOEXERCISEN/A67KJan 28, 2026
Oliveto JosephPresident and CEOSELL$50K–$100K44K$2.25Jan 9, 2026
Bharucha DavidChief Medical Offi…BUY$15K–$50K10K$4.74Dec 5, 2022
Wills Robert JamesDirectorBUY$50K–$100K15K$4.93Oct 21, 2022
Pasternak Richard CDirectorBUY$50K–$100K10K$5.20Oct 21, 2022
Liebert Debra K.DirectorBUY$50K–$100K14K$5.28Oct 21, 2022
TOMSICEK MICHAEL JOHNDirectorBUY$50K–$100K15K$5.32Oct 21, 2022
RTW INVESTMENTS, LP10% OwnerSELL$1M+1.6M$8.71Sep 9, 2022
RTW INVESTMENTS, LP10% OwnerBUY$1M+1.6M$8.71Sep 9, 2022
TRUEX PAUL FDirectorBUY$15K–$50K5K$5.60Jun 2, 2022
TRUEX PAUL FDirectorEXERCISE$100K–$500K77K$1.51Jun 2, 2022
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Institutional Ownership

13F filings as of Dec 31, 2025 · 54 funds holding

Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Propel Bio Management, LLC

SC 13G · Dec 23, 2025

9.9%

8.9M shares

Trails Edge Capital Partners, LP

SC 13G/A · Nov 14, 2025

9.9%

9.0M shares

RTW Investments, LP

SC 13G/A · Nov 14, 2025

9.9%

9.2M shares

Adage Capital Management, L.P.

SC 13G · Nov 13, 2025

10.0%

8.7M shares

Trails Edge Capital Partners, LP

SC 13G · Jul 21, 2025

9.9%

8.8M shares

Integrated Core Strategies (US) LLC

SC 13G/A · Apr 30, 2025

0.6%

322K shares

BlackRock, Inc.

SC 13G/A · Apr 22, 2025

0.0%

0 shares

RTW Investments, LP

SC 13G/A · Feb 14, 2025

10.0%

5.6M shares

BlackRock, Inc.

SC 13G/A · Feb 5, 2025

7.6%

4.1M shares

Integrated Core Strategies (US) LLC

SC 13G/A · Oct 29, 2024

5.1%

2.7M shares

Alta Fundamental Advisers LLC

SC 13D/A · Jul 16, 2024

5.0%

2.7M shares

2.8%

925K shares

RTW Investments, LP

SC 13G/A · Feb 14, 2024

10.0%

3.4M shares

THE GOLDMAN SACHS GROUP, INC.

SC 13G/A · Feb 10, 2024

4.1%

1.4M shares

Integrated Core Strategies (US) LLC

SC 13G/A · Jan 29, 2024

5.2%

1.7M shares

Alta Fundamental Advisers LLC

SC 13D · Nov 9, 2023

5.0%

1.7M shares

OrbiMed Capital LLC

SC 13G/A · Feb 14, 2023

0.0%

0 shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

6.4%

2.2M shares

Boxer Capital, LLC

SC 13G/A · Feb 14, 2023

2.0%

699K shares

Ikarian Capital, LLC

SC 13G/A · Feb 14, 2023

1.3%

460K shares

THE GOLDMAN SACHS GROUP, INC.

SC 13G · Jan 19, 2023

8.0%

2.8M shares

Integrated Core Strategies (US) LLC

SC 13G/A · Jan 18, 2023

5.5%

1.9M shares

5.3%

1.6M shares

Novo Holdings A/S

SC 13D/A · Oct 24, 2022

4.6%

1.4M shares

Novo Holdings A/S

SC 13D/A · Sep 26, 2022

7.0%

2.1M shares

6.9%

2.1M shares

Boxer Capital, LLC

SC 13G/A · Feb 14, 2022

0.224 shares

Ikarian Capital, LLC

SC 13G/A · Feb 14, 2022

5.9%

1.8M shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2022

7.5%

2.2M shares

RTW Investments, LP

SC 13G/A · Feb 14, 2022

14.4%

4.3M shares

OrbiMed Capital LLC

SC 13G/A · Feb 11, 2022

8.7%

2.6M shares

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