TSHA

Taysha Gene Therapies, Inc.

Biological Products, (No Diagnostic Substances)Nasdaq<br>Emerging growth company

Total Trades

33

Buys

12

Sells

17

Largest Trade

N/A

Insiders

8

Institutional Funds

143

Inst. Value

$1M+

Activist Filings

35

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Alam KamranCHIEF FINANCIAL OF…SELL$1K–$15K2K$4.52Feb 6, 2026
Nagendran SukumarPresident and Head…SELL$500K+116K$4.72Jan 27, 2026
Nolan Sean P.CEOSELL$500K+178K$4.72Jan 27, 2026
Alam KamranCHIEF FINANCIAL OF…SELL$100K–$500K103K$4.72Jan 27, 2026
Nagendran SukumarPresident and Head…SELL$500K+200K$4.71Jan 14, 2026
Nagendran SukumarPresident and Head…GRANTN/A427KJan 14, 2026
Nagendran SukumarPresident and Head…EXERCISE$100K–$500K200K$1.15Jan 14, 2026
Nagendran SukumarPresident and Head…SELL$1M+370K$4.58Dec 2, 2025
Nagendran SukumarPresident and Head…EXERCISE$500K+370K$1.52Dec 2, 2025
Nagendran SukumarPresident and Head…SELL$500K+200K$3.23Sep 12, 2025
Nagendran SukumarPresident and Head…EXERCISE$15K–$50K41K$0.70Sep 12, 2025
Nagendran SukumarPresident and Head…SELL$100K–$500K57K$2.85Aug 22, 2025
Alam KamranCHIEF FINANCIAL OF…SELL$100K–$500K54K$2.85Aug 22, 2025
Manning Paul B10% OwnerBUY$1M+750K$2.75Jun 4, 2025
Manning Paul B10% OwnerBUY$1M+1.3M$2.25Jul 1, 2024
Manning Paul B10% OwnerBUY$100K–$500K100K$1.63Nov 20, 2023
Alam KamranCFOSELL$50K–$100K33K$2.33Aug 25, 2023
Manning Paul B10% OwnerBUY$1M+16.5M$0.90Aug 17, 2023
Stalfort John A IIIDirectorBUY$500K+778K$0.90Aug 17, 2023
Nolan Sean P.CEOBUY$100K–$500K444K$0.90Aug 17, 2023
Donenberg Phillip B.DirectorBUY$50K–$100K111K$0.90Aug 17, 2023
Session R.A. II10% OwnerSELL$50K–$100K86K$0.71Jul 14, 2023
Session R.A. II10% OwnerSELL$15K–$50K29K$0.70Jun 26, 2023
Session R.A. II10% OwnerSELL$100K–$500K435K$0.71Jun 22, 2023
Nagendran SukumarPresident and Head…BUY$1K–$15K5K$0.68May 18, 2023
Manning Paul BDirectorBUY$1M+1.5M$2.00Nov 2, 2022
Alam KamranCFOSELL$1K–$15K3K$3.47Aug 24, 2022
Alam KamranCFOSELL$100K–$500K29K$3.70Aug 23, 2022
PRASAD SUYASHCMO and Head of R&DSELL$15K–$50K13K$3.71Jul 7, 2022
PRASAD SUYASHCMO and Head of R&DSELL$100K–$500K50K$3.65Jul 1, 2022
Manning Paul BDirectorBUY$1M+202K$7.80Feb 4, 2022
Nagendran SukumarDirectorBUY$50K–$100K10K$8.01Feb 3, 2022
Donenberg Phillip B.DirectorBUY$15K–$50K3K$7.78Feb 3, 2022
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

FMR LLC

SC 13G/A · Feb 5, 2026

4.9%

13.5M shares

BlackRock, Inc.

SC 13G/A · Jan 21, 2026

6.5%

17.9M shares

Octagon Capital Advisors LP

SC 13G/A · Nov 14, 2025

3.3%

9.1M shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2025

9.9%

27.7M shares

RA Capital Management, L.P.

SC 13G/A · Aug 14, 2025

9.9%

25.3M shares

RTW Investments, LP

SC 13G/A · Aug 14, 2025

9.9%

25.2M shares

Morgan Stanley

SC 13G/A · Aug 6, 2025

6.7%

16.9M shares

FMR LLC

SC 13G/A · Aug 6, 2025

6.2%

15.6M shares

BlackRock, Inc.

SC 13G/A · Jul 16, 2025

5.2%

13.2M shares

THE GOLDMAN SACHS GROUP, INC.

SC 13G · Jul 3, 2025

5.1%

12.7M shares

Paul B Manning

SC 13D/A · Jun 4, 2025

9.8%

25.6M shares

RTW Investments, LP

SC 13G/A · May 15, 2025

10.0%

20.7M shares

RTW Investments, LP

SC 13G/A · Feb 14, 2025

5.9%

12.4M shares

FMR LLC

SC 13G/A · Feb 12, 2025

8.0%

16.4M shares

Octagon Capital Advisors LP

SC 13G · Feb 5, 2025

5.1%

10.4M shares

Morgan Stanley

SC 13G · Feb 5, 2025

8.6%

17.6M shares

4.4%

9.0M shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2024

10.0%

21.5M shares

Avoro Capital Advisors LLC

SC 13G · Nov 14, 2024

10.0%

23.1M shares

FMR LLC

SC 13G/A · Nov 12, 2024

9.1%

18.7M shares

BlackRock, Inc.

SC 13G · Nov 8, 2024

6.6%

13.5M shares

BlackRock, Inc.

SC 13G · Oct 22, 2024

6.6%

13.5M shares

5.6%

10.4M shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2024

10.0%

18.7M shares

RTW Investments, LP

SC 13G · Feb 14, 2024

9.8%

18.5M shares

FMR LLC

SC 13G/A · Sep 11, 2023

15.0%

28.0M shares

7.7%

14.4M shares

RA Capital Management, L.P.

SC 13G · Aug 25, 2023

10.0%

18.7M shares

TCG Crossover GP I, LLC

SC 13G · Aug 25, 2023

5.9%

11.1M shares

Paul B. Manning

SC 13D/A · Aug 21, 2023

12.6%

23.5M shares

Astellas Pharma Inc.

SC 13D/A · Aug 18, 2023

3.9%

7.3M shares

FMR LLC

SC 13G/A · Nov 10, 2022

6.0%

3.3M shares

Paul B. Manning

SC 13D/A · Nov 2, 2022

11.2%

7.0M shares

Astellas Pharma Inc.

SC 13D · Oct 31, 2022

11.6%

7.3M shares

BlackRock, Inc.

SC 13G · Jul 8, 2022

2.6%

1.0M shares

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