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RTW Investments, LP

Activist investor & 5%+ owner · SC 13D/13G filings

Total Filings

219

Stocks Covered

89

Latest Filing

Nov 14, 2025

Filings

Axsome Therapeutics, Inc.

SC 13G · Feb 14, 2023

6.9%

3.0M shares

Jounce Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

9.9%

5.1M shares

Immunic, Inc.

SC 13G/A · Feb 14, 2023

8.7%

3.9M shares

La Jolla Pharmaceutical Company

SC 13G/A · Feb 14, 2023

0.0%

0 shares

IVERIC bio, Inc.

SC 13G/A · Feb 14, 2023

0.6%

821K shares

Prometheus Biosciences, Inc.

SC 13G/A · Feb 14, 2023

7.2%

3.4M shares

Oyster Point Pharma, Inc.

SC 13G/A · Feb 14, 2023

8.6%

2.3M shares

Immunocore Holdings plc

SC 13G · Feb 14, 2023

12.3%

5.6M shares

Fulcrum Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

9.6%

5.0M shares

Protagonist Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

7.3%

3.6M shares

ESSA Pharma Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Establishment Labs Holdings Inc.

SC 13G/A · Feb 14, 2023

9.8%

2.4M shares

PTC Therapeutics, Inc.

SC 13G/A · Feb 14, 2023

7.7%

5.6M shares

Cutera, Inc.

SC 13G/A · Feb 14, 2023

9.2%

1.8M shares

Avadel Pharmaceuticals PLC

SC 13G/A · Feb 14, 2023

9.3%

5.7M shares

Exagen Inc.

SC 13G/A · Feb 14, 2023

8.4%

1.4M shares

Adicet Bio, Inc.

SC 13G/A · Feb 14, 2023

9.9%

4.2M shares

Pyxis Oncology, Inc.

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Avidity Biosciences, Inc.

SC 13D/A · Feb 2, 2023

59.0%

6.0M shares

Orchestra Biomed Holdings, Inc.

SC 13D/A · Jan 27, 2023

16.2%

5.1M shares

Immunovant, Inc.

SC 13G/A · Dec 5, 2022

0.0%

0 shares

Immunovant, Inc.

SC 13G/A · Dec 2, 2022

5.9%

7.6M shares

DermTech, Inc.

SC 13D/A · Nov 8, 2022

60.0%

3.0M shares

Landos Biopharma, Inc.

SC 13D/A · Nov 3, 2022

50.0%

0 shares

Landos Biopharma, Inc.

SC 13D/A · Oct 31, 2022

57.8%

3.2M shares

Health Sciences Acquisitions Corporation 2

SC 13D · Oct 12, 2022

8.9%

1.0M shares

Rocket Pharmaceuticals, Inc.

SC 13D/A · Oct 11, 2022

524.3%

17.6M shares

Landos Biopharma, Inc.

SC 13D/A · Oct 6, 2022

59.1%

3.7M shares

Rocket Pharmaceuticals, Inc.

SC 13D/A · Sep 21, 2022

524.6%

16.3M shares

Renovacor, Inc.

SC 13D · Sep 21, 2022

519.0%

3.4M shares

Arbutus Biopharma Corporation

SC 13G/A · Feb 14, 2022

1.7%

2.5M shares

Agenus Inc.

SC 13G/A · Feb 14, 2022

2.3%

5.9M shares

Science 37 Holdings, Inc. (formerly known as Lifesci Acquisition II Corp.)

SC 13G/A · Feb 14, 2022

3.5%

4.0M shares

Vincerx Pharma, Inc.

SC 13G/A · Feb 14, 2022

3.5%

741K shares

C4 Therapeutics, Inc.

SC 13G · Feb 14, 2022

5.1%

2.5M shares

Tenaya Therapeutics, Inc.

SC 13G · Feb 14, 2022

6.0%

2.5M shares

La Jolla Pharmaceutical Company

SC 13G/A · Feb 14, 2022

9.3%

2.6M shares

CytomX Therapeutics, Inc.

SC 13G/A · Feb 14, 2022

9.2%

6.0M shares

Exagen Inc.

SC 13G/A · Feb 14, 2022

5.1%

821K shares

Jounce Therapeutics, Inc.

SC 13G · Feb 14, 2022

5.6%

2.9M shares

ASLAN Pharmaceuticals Limited

SC 13G · Feb 14, 2022

6.8%

16.3M shares

Pyxis Oncology, Inc.

SC 13G · Feb 14, 2022

6.5%

2.1M shares

Macrogenics, Inc.

SC 13G · Feb 14, 2022

6.5%

4.0M shares

Adverum Biotechnologies, Inc.

SC 13G/A · Feb 14, 2022

7.7%

7.6M shares

Cutera, Inc.

SC 13G/A · Feb 14, 2022

7.8%

1.4M shares

ESSA Pharma Inc.

SC 13G/A · Feb 14, 2022

6.0%

2.6M shares

Oyster Point Pharma, Inc.

SC 13G/A · Feb 14, 2022

7.9%

2.1M shares

Clearside Biomedical, Inc.

SC 13G/A · Feb 14, 2022

6.4%

3.8M shares

Relmada Therapeutics, Inc.

SC 13G/A · Feb 14, 2022

7.9%

2.2M shares

IDEAYA Biosciences, Inc.

SC 13G/A · Feb 14, 2022

6.5%

2.5M shares