C4 Therapeutics, Inc.
Total Trades
5
Buys
2
Sells
2
Largest Trade
$100K–$500K
Insiders
4
Institutional Funds
70
Inst. Value
$1M+
Activist Filings
48
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| REYNO LEONARD | Chief Medical Offi… | SELL | $15K–$50K | 10K | $2.22 | Jan 16, 2026 |
| Koppikar Utpal | Director | BUY | $15K–$50K | 6K | $5.60 | Feb 10, 2023 |
| Hirsch Andrew | President & CEO | BUY | $50K–$100K | 10K | $8.40 | Apr 12, 2022 |
| Crystal Adam | Chief Medical Offi… | EXERCISE | $50K–$100K | 15K | $6.49 | Jan 5, 2022 |
| Crystal Adam | Chief Medical Offi… | SELL | $100K–$500K | 15K | $31.66 | Jan 5, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 70 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| Point72 Asset Management, L.P. | 9.4M | $1M+ | SH |
| RA CAPITAL MANAGEMENT, L.P. | 8.0M | $1M+ | SH |
| Bain Capital Life Sciences Investors, LLC | 7.2M | $1M+ | SH |
| WASATCH ADVISORS LP | 4.3M | $1M+ | SH |
| VANGUARD GROUP INC | 3.9M | $1M+ | SH |
| Soleus Capital Management, L.P. | 3.8M | $1M+ | SH |
| SILVERARC CAPITAL MANAGEMENT, LLC | 2.0M | $1M+ | SH |
| RENAISSANCE TECHNOLOGIES LLC | 1.6M | $1M+ | SH |
| ORBIMED ADVISORS LLC | 1.4M | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 804K | $1M+ | SH |
| ACADIAN ASSET MANAGEMENT LLC | 657K | $1M+ | SH |
| WELLS FARGO & COMPANY/MN | 600K | $1M+ | SH |
| JANE STREET GROUP, LLC | 510K | $500K+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 449K | $500K+ | SH |
| Walleye Capital LLC | 443K | $500K+ | SH |
| STATE STREET CORP | 343K | $500K+ | SH |
| DIMENSIONAL FUND ADVISORS LP | 277K | $500K+ | SH |
| LPL Financial LLC | 243K | $100K–$500K | SH |
| Hennion & Walsh Asset Management, Inc. | 237K | $100K–$500K | SH |
| ArrowMark Colorado Holdings LLC | 205K | $100K–$500K | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G/A · Feb 17, 2026
7.3%
7.1M shares
Soleus Private Equity Fund III, L.P.
SC 13G/A · Feb 12, 2026
5.9%
6.1M shares
SC 13G/A · Feb 11, 2026
9.3%
9.0M shares
SC 13G/A · Nov 14, 2025
2.3%
1.7M shares
SC 13G/A · Nov 13, 2025
6.8%
4.9M shares
Bain Capital Life Sciences Fund II, L.P.
SC 13G · Oct 24, 2025
1.1%
991K shares
SC 13G · Oct 24, 2025
9.9%
9.4M shares
Point72 Asset Management, L.P.
SC 13G · Oct 20, 2025
9.9%
22.6M shares
SC 13G/A · Aug 7, 2025
6.7%
4.8M shares
SC 13G/A · Jul 16, 2025
2.5%
1.8M shares
SC 13G/A · May 16, 2025
3.1%
2.2M shares
SC 13G/A · May 15, 2025
0.0%
0 shares
SC 13G/A · May 7, 2025
10.5%
7.5M shares
SC 13G · Feb 3, 2025
5.4%
3.8M shares
Point72 Asset Management, L.P.
SC 13G/A · Nov 15, 2024
1.9%
1.3M shares
SC 13G · Nov 14, 2024
2.1%
1.5M shares
SC 13G/A · Nov 14, 2024
4.8%
3.4M shares
Soleus Capital Master Fund, L.P.
SC 13G/A · Nov 14, 2024
9.4%
6.6M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Nov 14, 2024
0.6%
392K shares
SC 13G/A · Nov 14, 2024
9.9%
6.9M shares
SC 13G · Nov 8, 2024
7.1%
4.9M shares
SC 13G · Oct 22, 2024
7.1%
4.9M shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G/A · Jul 10, 2024
4.3%
0 shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G · Apr 10, 2024
10.4%
0 shares
Wasatch Advisors LP 87-0319391
SC 13G/A · Mar 8, 2024
8.0%
5.5M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2024
5.2%
2.6M shares
SC 13G/A · Feb 14, 2024
6.4%
3.1M shares
SC 13G/A · Feb 14, 2024
0.0%
0 shares
Soleus Capital Master Fund, L.P.
SC 13G/A · Feb 2, 2024
3.7%
1.8M shares
Betta Investment (Hong Kong) Limited
SC 13G · Jan 12, 2024
8.1%
5.6M shares
Point72 Asset Management, L.P.
SC 13G · Jan 4, 2024
4.7%
2.3M shares
SC 13G · Dec 26, 2023
9.9%
4.9M shares
SC 13G · Dec 22, 2023
7.7%
3.8M shares
SC 13G · Nov 13, 2023
6.3%
3.1M shares
SC 13G · Jul 25, 2023
4.8%
2.4M shares
SC 13G/A · Jul 7, 2023
4.3%
2.1M shares
ArrowMark Colorado Holdings, LLC
SC 13G/A · Jun 12, 2023
3.0%
1.5M shares
Soleus Capital Master Fund, L.P.
SC 13G · Apr 14, 2023
5.0%
2.5M shares
ArrowMark Colorado Holdings, LLC
SC 13G · Feb 14, 2023
11.8%
5.8M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2023
6.0%
2.9M shares
SC 13G/A · Feb 14, 2023
5.8%
2.8M shares
SC 13G/A · Jan 31, 2023
7.4%
3.6M shares
ArrowMark Colorado Holdings, LLC
SC 13G · Jun 10, 2022
11.1%
5.4M shares
Wasatch Advisors, Inc. 87-0319391
SC 13G/A · Jun 6, 2022
10.2%
5.0M shares
SC 13G/A · Feb 14, 2022
4.5%
2.2M shares
Cormorant Global Healthcare Master Fund, LP
SC 13G/A · Feb 14, 2022
0.0%
0 shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G · Feb 14, 2022
8.4%
4.1M shares
SC 13G · Feb 14, 2022
5.1%
2.5M shares