RNA

Avidity Biosciences, Inc.

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

132

Buys

0

Sells

81

Largest Trade

N/A

Insiders

12

Institutional Funds

268

Inst. Value

$1M+

Activist Filings

50

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Hughes Steven GeorgeChief Medical Offi…SELL$100K–$500K5K$72.45Jan 23, 2026
Boyce SarahPresident and CEOSELL$1M+14K$72.45Jan 23, 2026
Flanagan W. MichaelChief Scientific O…SELL$100K–$500K7K$72.45Jan 23, 2026
MacLean Michael FCFOSELL$100K–$500K5K$72.45Jan 23, 2026
LEVIN ARTHUR ADirectorSELL$100K–$500K2K$72.45Jan 23, 2026
McCarthy TeresaCHROSELL$100K–$500K3K$72.45Jan 23, 2026
Boyce SarahPresident and CEOSELL$500K+9K$72.23Jan 9, 2026
Calderaro Charles IIIChief Technical Of…SELL$100K–$500K4K$72.23Jan 9, 2026
McCarthy TeresaCHROSELL$100K–$500K2K$72.23Jan 9, 2026
Moriarty John BChief Legal OfficerSELL$100K–$500K2K$72.23Jan 9, 2026
MacLean Michael FCFOSELL$100K–$500K2K$72.23Jan 9, 2026
Hughes Steven GeorgeChief Medical Offi…SELL$100K–$500K2K$72.23Jan 9, 2026
Flanagan W. MichaelChief Scientific O…SELL$100K–$500K2K$72.23Jan 9, 2026
Hughes Steven GeorgeChief Medical Offi…EXERCISE$15K–$50K2K$10.16Oct 24, 2025
Hughes Steven GeorgeChief Medical Offi…SELL$100K–$500K2K$47.54Oct 24, 2025
Hughes Steven GeorgeChief Medical Offi…SELL$50K–$100K2K$40.58Sep 23, 2025
Hughes Steven GeorgeChief Medical Offi…EXERCISE$15K–$50K2K$10.16Sep 23, 2025
McCarthy TeresaCHROEXERCISE$100K–$500K15K$22.34Sep 17, 2025
McCarthy TeresaCHROSELL$500K+15K$41.41Sep 17, 2025
Hughes Steven GeorgeChief Medical Offi…EXERCISE$1K–$15K2K$6.57Sep 17, 2025
Hughes Steven GeorgeChief Medical Offi…SELL$50K–$100K2K$45.41Sep 17, 2025
Flanagan W. MichaelChief Scientific O…EXERCISE$100K–$500K20K$14.22Sep 12, 2025
Flanagan W. MichaelChief Scientific O…SELL$500K+20K$38.94Sep 12, 2025
WILSON TROY EDWARDDirectorSELL$1M+30K$50.00Sep 9, 2025
WILSON TROY EDWARDDirectorEXERCISE$100K–$500K15K$12.48Sep 9, 2025
Boyce SarahPresident and CEOSELL$1M+50K$49.95Sep 5, 2025
Boyce SarahPresident and CEOEXERCISE$50K–$100K50K$1.24Sep 5, 2025
Mosbrooker EricChief Commercial O…EXERCISE$50K–$100K7K$9.05Sep 5, 2025
Mosbrooker EricChief Commercial O…SELL$100K–$500K7K$47.07Sep 5, 2025
Gallagher Kathleen P.Chief Program Offi…SELL$1K–$15K188$47.42Sep 3, 2025
Boyce SarahPresident and CEOEXERCISE$15K–$50K25K$1.24Aug 29, 2025
Boyce SarahPresident and CEOSELL$1M+25K$49.39Aug 29, 2025
Hughes Steven GeorgeChief Medical Offi…EXERCISE$15K–$50K2K$10.16Aug 22, 2025
Hughes Steven GeorgeChief Medical Offi…SELL$100K–$500K2K$46.40Aug 22, 2025
Gallagher Kathleen P.Chief Program Offi…SELL$15K–$50K911$30.24Jun 18, 2025
Flanagan W. MichaelChief Scientific O…EXERCISE$100K–$500K20K$14.22Jun 12, 2025
Flanagan W. MichaelChief Scientific O…SELL$500K+20K$32.88Jun 12, 2025
Gallagher Kathleen P.Chief Program Offi…EXERCISE$50K–$100K6K$16.65Jun 4, 2025
Gallagher Kathleen P.Chief Program Offi…SELL$100K–$500K6K$32.48Jun 4, 2025
Gallagher Kathleen P.Chief Program Offi…SELL$100K–$500K6K$32.40May 2, 2025
Gallagher Kathleen P.Chief Program Offi…EXERCISE$50K–$100K6K$16.65May 2, 2025
Gallagher Kathleen P.Chief Program Offi…EXERCISE$50K–$100K6K$14.81Apr 3, 2025
Gallagher Kathleen P.Chief Program Offi…SELL$100K–$500K6K$27.83Apr 3, 2025
Hughes Steven GeorgeChief Medical Offi…SELL$100K–$500K10K$31.06Mar 21, 2025
Boyce SarahPresident and CEOSELL$500K+32K$31.06Mar 21, 2025
Flanagan W. MichaelChief Scientific O…SELL$100K–$500K12K$31.06Mar 21, 2025
MacLean Michael FCFOSELL$100K–$500K8K$31.06Mar 21, 2025
McCarthy TeresaCHROSELL$100K–$500K8K$31.06Mar 21, 2025
Flanagan W. MichaelChief Scientific O…EXERCISE$100K–$500K20K$14.22Mar 12, 2025
Flanagan W. MichaelChief Scientific O…SELL$500K+20K$30.13Mar 12, 2025
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Feb 17, 2026

4.6%

6.9M shares

Wellington Management Group LLP

SC 13G/A · Feb 10, 2026

0.5%

723K shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Dec 5, 2025

5.5%

8.2M shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2025

5.9%

8.6M shares

T. Rowe Price Associates, Inc.

SC 13G/A · Nov 14, 2025

7.1%

9.8M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Nov 14, 2025

10.7%

14.5M shares

FMR LLC

SC 13G/A · Nov 7, 2025

2.1%

3.0M shares

FMR LLC

SC 13G/A · Nov 5, 2025

15.0%

21.5M shares

The Vanguard Group

SC 13G/A · Oct 30, 2025

9.6%

13.2M shares

RTW Investments, LP

SC 13D/A · Oct 30, 2025

3.1%

4.7M shares

BlackRock, Inc.

SC 13G/A · Oct 17, 2025

6.4%

8.6M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Aug 7, 2025

10.1%

12.1M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · May 14, 2025

9.5%

11.5M shares

Wellington Management Group LLP

SC 13G/A · May 12, 2025

8.1%

9.7M shares

FMR LLC

SC 13G/A · May 12, 2025

13.0%

15.6M shares

BlackRock, Inc.

SC 13G/A · Apr 17, 2025

7.5%

9.0M shares

JANUS HENDERSON GROUP PLC

SC 13G · Feb 14, 2025

5.9%

7.1M shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2024

5.4%

6.3M shares

9.0%

10.6M shares

Avoro Capital Advisors LLC

SC 13G · Nov 14, 2024

8.3%

9.9M shares

0.0%

0 shares

Bristol-Myers Squibb Company

SC 13G/A · Nov 13, 2024

4.3%

5.1M shares

The Vanguard Group

SC 13G/A · Nov 12, 2024

7.8%

9.2M shares

Wellington Management Group LLP

SC 13G · Nov 8, 2024

6.0%

7.0M shares

The Vanguard Group

SC 13G/A · Nov 4, 2024

7.8%

9.2M shares

RTW Investments, LP

SC 13D/A · Aug 23, 2024

60.0%

12.1M shares

RA Capital Management, L.P.

SC 13G · May 6, 2024

5.1%

4.9M shares

12.1%

9.7M shares

RTW Investments, LP

SC 13D/A · Mar 1, 2024

60.0%

9.7M shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2024

3.3%

2.5M shares

9.3%

6.9M shares

The Vanguard Group - 23-1945930

SC 13G/A · Feb 13, 2024

5.5%

4.0M shares

7.6%

5.6M shares

BlackRock, Inc.

SC 13G/A · Jan 25, 2024

8.8%

6.5M shares

RTW Investments, LP

SC 13D/A · Jan 24, 2024

58.4%

6.7M shares

Bristol-Myers Squibb Company

SC 13G · Dec 4, 2023

6.4%

5.1M shares

FMR LLC

SC 13G/A · Jul 10, 2023

15.0%

10.6M shares

EcoR1 Capital, LLC

SC 13G/A · Feb 14, 2023

0.0%

0 shares

10.1%

6.7M shares

BlackRock, Inc.

SC 13G/A · Feb 3, 2023

8.0%

5.3M shares

RTW Investments, LP

SC 13D/A · Feb 2, 2023

59.0%

6.0M shares

6.5%

5.2M shares

RA Capital Management, L.P.

SC 13G · Dec 30, 2022

8.2%

5.5M shares

1.8%

1.0M shares

6.6%

3.3M shares

10.2%

5.1M shares

0.5%

250K shares

EcoR1 Capital, LLC

SC 13G/A · Feb 14, 2022

5.9%

2.8M shares

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