OBIO

Orchestra BioMed Holdings, Inc.

Surgical & Medical Instruments & ApparatusNasdaq<br>Emerging growth company

Total Trades

14

Buys

13

Sells

1

Largest Trade

$100K–$500K

Insiders

8

Institutional Funds

42

Inst. Value

$1M+

Activist Filings

22

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Hochman David PSee RemarksBUY$15K–$50K5K$4.07Nov 17, 2025
Aryeh JasonDirectorBUY$1K–$15K1K$2.45Sep 19, 2025
Fain Eric SDirectorBUY$15K–$50K6K$2.61Aug 25, 2025
Sherman DarrenSee RemarksBUY$1K–$15K3K$2.62Aug 25, 2025
Hochman David PSee RemarksBUY$1K–$15K6K$2.49Aug 25, 2025
Taylor Andrew LawrenceCFOBUY$1K–$15K2K$2.55Aug 25, 2025
Fain Eric SDirectorSELL$1K–$15K3K$3.05Jun 27, 2025
RTW INVESTMENTS, LP10% OwnerBUY$100K–$500K50K$2.99May 1, 2025
RTW INVESTMENTS, LP10% OwnerBUY$100K–$500K50K$2.53Apr 29, 2025
Hochman David PSee RemarksBUY$15K–$50K4K$4.66Dec 26, 2024
Hochman David PSee RemarksBUY$15K–$50K10K$4.79Sep 26, 2024
Hochman David PSee RemarksBUY$1K–$15K1K$6.95Jun 26, 2024
Little William ReedSee RemarksBUY$15K–$50K4K$7.00Jun 3, 2024
Medtronic plc10% OwnerBUY$50K–$100K7K$9.28Feb 1, 2023
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Institutional Ownership

13F filings as of Dec 31, 2025 · 42 funds holding

Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Medtronic plc

SC 13G/A · Feb 27, 2026

17.8%

10.1M shares

RTW Investments, LP

SC 13D/A · Feb 25, 2026

19.7%

11.9M shares

Tasso Partners, LLC

SC 13G · Nov 19, 2025

5.0%

2.8M shares

Perceptive Advisors LLC

SC 13G/A · Nov 14, 2025

10.0%

5.7M shares

RTW Investments, LP

SC 13D/A · Aug 6, 2025

15.4%

8.3M shares

RTW Investments, LP

SC 13D/A · May 1, 2025

21.7%

8.3M shares

BlackRock, Inc.

SC 13G/A · Apr 29, 2025

3.7%

1.4M shares

Medtronic plc

SC 13G/A · Feb 14, 2025

15.4%

5.9M shares

BlackRock, Inc.

SC 13G · Nov 8, 2024

5.1%

1.9M shares

BlackRock, Inc.

SC 13G · Oct 23, 2024

5.1%

1.9M shares

RTW Investments, LP 2

SC 13D/A · Aug 7, 2024

21.5%

770.4M shares

HSAC 2 Holdings, LLC 2

SC 13D/A · Aug 7, 2024

4.8%

170.6M shares

Perceptive Advisors LLC

SC 13G/A · Jul 17, 2024

12.8%

4.6M shares

Perceptive Advisors LLC

SC 13G/A · Feb 14, 2024

6.8%

2.4M shares

Medtronic plc

SC 13G/A · Feb 14, 2024

16.4%

5.9M shares

1.7%

623K shares

Perceptive Advisors LLC

SC 13G · Sep 13, 2023

6.8%

2.4M shares

RTW Investments, LP

SC 13D/A · May 5, 2023

15.7%

5.6M shares

RA Capital Management, L.P.

SC 13G · Feb 14, 2023

5.4%

610K shares

6.1%

686K shares

HSAC 2 Holdings, LLC

SC 13D/A · Jan 30, 2023

16.2%

5.1M shares

RTW Investments, LP

SC 13D/A · Jan 27, 2023

16.2%

5.1M shares

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