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RA Capital Management, L.P.

Activist investor & 5%+ owner · SC 13D/13G filings

Total Filings

441

Stocks Covered

166

Latest Filing

Feb 17, 2026

Filings

Kura Oncology, Inc.

SC 13G · Dec 5, 2024

5.6%

4.4M shares

Cidara Therapeutics, Inc.

SC 13D/A · Nov 26, 2024

10.0%

1.1M shares

Arcellx, Inc.

SC 13G · Nov 22, 2024

5.2%

2.8M shares

89bio, Inc.

SC 13D/A · Nov 19, 2024

11.9%

14.3M shares

4D MOLECULAR THERAPEUTICS, INC.

SC 13G/A · Nov 15, 2024

11.0%

5.1M shares

Sera Prognostics, Inc.

SC 13G/A · Nov 14, 2024

9.4%

3.0M shares

Astria Therapeutics, Inc.

SC 13G/A · Nov 14, 2024

9.0%

5.1M shares

CELCUITY INC.

SC 13G/A · Nov 14, 2024

3.4%

1.3M shares

GERON CORPORATION

SC 13G/A · Nov 14, 2024

10.0%

63.3M shares

Ascendis Pharma A/S

SC 13G/A · Nov 14, 2024

16.1%

9.7M shares

Bicycle Therapeutics plc

SC 13G/A · Nov 14, 2024

4.7%

2.3M shares

Dyne Therapeutics, Inc.

SC 13G/A · Nov 14, 2024

6.4%

6.4M shares

UROGEN PHARMA LTD.

SC 13G/A · Nov 14, 2024

7.1%

3.2M shares

RxSIGHT, Inc.

SC 13G/A · Nov 14, 2024

9.9%

3.9M shares

Praxis Precision Medicines, Inc.

SC 13G/A · Nov 14, 2024

4.3%

762K shares

TAYSHA GENE THERAPIES, INC.

SC 13G/A · Nov 14, 2024

10.0%

21.5M shares

Structure Therapeutics Inc.

SC 13G/A · Nov 14, 2024

3.3%

5.7M shares

Regulus Therapeutics Inc.

SC 13G/A · Nov 14, 2024

1.2%

767K shares

4D MOLECULAR THERAPEUTICS, INC.

SC 13G/A · Nov 14, 2024

10.0%

5.2M shares

NEWAMSTERDAM PHARMA COMPANY N.V.

SC 13G/A · Nov 14, 2024

10.0%

9.1M shares

Tenaya Therapeutics, Inc.

SC 13G/A · Nov 14, 2024

10.0%

8.0M shares

Tourmaline Bio, Inc.

SC 13G/A · Nov 14, 2024

9.9%

2.5M shares

UNICYCIVE THERAPEUTICS, INC.

SC 13G/A · Nov 14, 2024

10.0%

10.5M shares

THIRD HARMONIC BIO, INC.

SC 13G/A · Nov 14, 2024

3.1%

1.3M shares

Apogee Therapeutics, Inc.

SC 13G/A · Nov 14, 2024

3.4%

2.0M shares

RHYTHM PHARMACEUTICALS, INC.

SC 13G/A · Nov 14, 2024

9.9%

6.1M shares

ENLIVEN THERAPEUTICS, INC.

SC 13G/A · Nov 14, 2024

2.2%

1.1M shares

Avidity Biosciences, Inc.

SC 13G/A · Nov 14, 2024

5.4%

6.3M shares

GH Research PLC

SC 13G/A · Nov 14, 2024

12.9%

6.7M shares

VAXCYTE, INC.

SC 13G/A · Nov 14, 2024

10.0%

12.6M shares

Alto Neuroscience, Inc.

SC 13G/A · Nov 14, 2024

7.7%

2.1M shares

Adicet Bio, Inc.

SC 13G/A · Nov 14, 2024

10.0%

8.3M shares

Verona Pharma plc

SC 13G/A · Nov 14, 2024

10.0%

8.5M shares

Tyra Biosciences, Inc.

SC 13D/A · Nov 13, 2024

21.1%

10.7M shares

Bright Minds Biosciences Inc.

SC 13G · Nov 12, 2024

6.6%

461K shares

GlycoMimetics, Inc.

SC 13G · Nov 6, 2024

9.9%

6.4M shares

Ensysce Biosciences, Inc.

SC 13G · Nov 6, 2024

9.9%

1.5M shares

Eledon Pharmaceuticals, Inc.

SC 13G · Nov 5, 2024

6.1%

3.6M shares

Septerna, Inc.

SC 13D · Nov 4, 2024

15.8%

7.0M shares

Monopar Therapeutics Inc.

SC 13G · Oct 31, 2024

9.7%

511K shares

Tyra Biosciences, Inc.

SC 13D/A · Oct 22, 2024

20.0%

10.1M shares

Janux Therapeutics, Inc.

SC 13D/A · Oct 22, 2024

20.0%

10.4M shares

BioAge Labs, Inc.

SC 13G · Oct 7, 2024

6.2%

2.2M shares

Wave Life Sciences Ltd.

SC 13D/A · Oct 1, 2024

16.0%

25.4M shares

Bicara Therapeutics, Inc.

SC 13D · Sep 23, 2024

12.8%

7.0M shares

Janux Therapeutics, Inc.

SC 13D/A · Sep 17, 2024

20.0%

10.7M shares

Fulcrum Therapeutics, Inc.

SC 13G/A · Sep 17, 2024

19.3%

10.2M shares

Artiva Biotherapeutics, Inc.

SC 13D/A · Sep 3, 2024

40.6%

9.9M shares

Avalo Therapeutics, Inc.

SC 13G · Aug 23, 2024

10.0%

967K shares

Fulcrum Therapeutics, Inc.

SC 13G/A · Aug 23, 2024

10.0%

5.5M shares