SEPN
Septerna, Inc.
Pharmaceutical PreparationsNasdaq<br>Emerging growth company
Total Trades
12
Buys
7
Sells
3
Largest Trade
$1M+
Insiders
8
Institutional Funds
85
Inst. Value
$1M+
Activist Filings
10
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Shaikhly Samira | Chief People Officer | EXERCISE | $100K–$500K | 70K | $1.84 | Mar 5, 2026 |
| Shaikhly Samira | Chief People Officer | SELL | $1M+ | 70K | $28.10 | Mar 5, 2026 |
| Bhatt Elizabeth | President and COO | SELL | $100K–$500K | 4K | $28.97 | Feb 20, 2026 |
| Bhatt Elizabeth | President and COO | EXERCISE | $15K–$50K | 4K | $6.81 | Feb 20, 2026 |
| Long Daniel D. | SVP, Drug Discovery | SELL | $50K–$100K | 4K | $18.06 | Nov 14, 2025 |
| Finer Jeffrey | CEO and President | BUY | $50K–$100K | 17K | $5.70 | Feb 27, 2025 |
| Labrucherie Gil M | CFO | BUY | $50K–$100K | 10K | $5.69 | Feb 27, 2025 |
| Third Rock Ventures VI, L.P. | 10% Owner | BUY | $100K–$500K | 19K | $6.00 | Feb 26, 2025 |
| Third Rock Ventures VI, L.P. | 10% Owner | BUY | $1M+ | 1.0M | $5.93 | Feb 24, 2025 |
| Labrucherie Gil M | CFO | BUY | $100K–$500K | 30K | $5.74 | Feb 21, 2025 |
| RA CAPITAL MANAGEMENT, L.P. | Director | BUY | $1M+ | 4.2M | $18.00 | Oct 30, 2024 |
| Third Rock Ventures V, L.P. | 10% Owner | BUY | $1M+ | 650K | $18.00 | Oct 28, 2024 |
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Institutional Ownership
13F filings as of Dec 31, 2025 · 85 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 7.0M | $1M+ | SH |
| TRV GP V, LLC | 6.2M | $1M+ | SH |
| TRV GP VI, LLC | 4.2M | $1M+ | SH |
| Samsara BioCapital, LLC | 3.1M | $1M+ | SH |
| Siren, L.L.C. | 2.0M | $1M+ | SH |
| GOLDMAN SACHS GROUP INC | 1.3M | $1M+ | SH |
| ADAR1 Capital Management, LLC | 1.2M | $1M+ | SH |
| ADAR1 Capital Management, LLC | 1.2M | $1M+ | SH |
| First Light Asset Management, LLC | 621K | $1M+ | SH |
| VR Adviser, LLC | 611K | $1M+ | SH |
| PRIMECAP MANAGEMENT CO/CA/ | 546K | $1M+ | SH |
| STATE STREET CORP | 540K | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 500K | $1M+ | SH |
| PERCEPTIVE ADVISORS LLC | 433K | $1M+ | SH |
| Soleus Capital Management, L.P. | 383K | $1M+ | SH |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 223K | $1M+ | SH |
| Kalehua Capital Management LLC | 195K | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 187K | $1M+ | SH |
| VANGUARD GROUP INC | 150K | $1M+ | SH |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 61K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G/A · Feb 17, 2026
2.0%
920K shares
DRIEHAUS CAPITAL MANAGEMENT LLC
SC 13G/A · Jun 10, 2025
10.5%
4.7M shares
SC 13G/A · May 15, 2025
5.2%
2.3M shares
DRIEHAUS CAPITAL MANAGEMENT LLC
SC 13G/A · May 15, 2025
7.0%
3.1M shares
SC 13G/A · May 9, 2025
14.0%
6.2M shares
DRIEHAUS CAPITAL MANAGEMENT LLC
SC 13G · Feb 14, 2025
5.8%
2.6M shares
SC 13G · Feb 13, 2025
14.0%
6.2M shares
SC 13D · Nov 4, 2024
15.8%
7.0M shares
SC 13G · Nov 4, 2024
6.2%
2.8M shares
Biotechnology Value Fund, L.P.
SC 13G · Nov 1, 2024
2.9%
1.3M shares