RYTM

RHYTHM PHARMACEUTICALS, INC.

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

152

Buys

0

Sells

83

Largest Trade

N/A

Insiders

13

Institutional Funds

217

Inst. Value

$1M+

Activist Filings

46

Insider Trades

InsiderTitleTypeValueSharesPriceDate
German Christopher PaulCorporate Controll…SELL$500K+6K$89.56Mar 6, 2026
German Christopher PaulCorporate Controll…EXERCISE$15K–$50K2K$17.97Mar 6, 2026
Smith Hunter CCFOSELL$500K+7K$100.21Feb 13, 2026
Smith Hunter CCFOSELL$500K+7K$106.03Feb 6, 2026
Cramer Pamela J.CHROSELL$100K–$500K3K$111.00Dec 15, 2025
Cramer Pamela J.CHROEXERCISE$50K–$100K3K$27.35Dec 15, 2025
Cramer Pamela J.CHROEXERCISE$50K–$100K3K$27.35Nov 24, 2025
Cramer Pamela J.CHROSELL$100K–$500K3K$105.00Nov 24, 2025
Cramer Pamela J.CHROSELL$1M+23K$99.00Nov 12, 2025
Cramer Pamela J.CHROEXERCISE$100K–$500K23K$11.51Nov 12, 2025
Shulman JosephChief Technical Of…SELL$1M+10K$115.24Nov 3, 2025
Shulman JosephChief Technical Of…EXERCISE$100K–$500K10K$30.66Nov 3, 2025
Shulman JosephChief Technical Of…SELL$100K–$500K3K$115.01Oct 30, 2025
Shulman JosephChief Technical Of…EXERCISE$50K–$100K3K$28.20Oct 30, 2025
Shulman JosephChief Technical Of…EXERCISE$100K–$500K14K$30.18Oct 20, 2025
Shulman JosephChief Technical Of…SELL$1M+14K$112.03Oct 20, 2025
Shulman JosephChief Technical Of…EXERCISE$500K+17K$30.25Sep 4, 2025
Shulman JosephChief Technical Of…SELL$1M+17K$105.30Sep 4, 2025
Shulman JosephChief Technical Of…EXERCISE$100K–$500K4K$27.35Aug 26, 2025
Shulman JosephChief Technical Of…SELL$100K–$500K4K$100.07Aug 26, 2025
Cramer Pamela J.CHROSELL$100K–$500K2K$85.93Jul 29, 2025
Cramer Pamela J.CHROEXERCISEN/A3KJul 29, 2025
Smith Hunter CCFOSELL$1M+42K$80.48Jul 11, 2025
Smith Hunter CCFOEXERCISE$100K–$500K42K$6.88Jul 11, 2025
Shulman JosephChief Technical Of…EXERCISE$50K–$100K8K$6.80Jul 11, 2025
Shulman JosephChief Technical Of…SELL$500K+8K$77.78Jul 11, 2025
German Christopher PaulCorporate Controll…EXERCISE$50K–$100K3K$27.29Jul 11, 2025
German Christopher PaulCorporate Controll…SELL$100K–$500K4K$80.75Jul 11, 2025
Cramer Pamela J.CHROEXERCISE$100K–$500K16K$13.43Jul 11, 2025
Cramer Pamela J.CHROSELL$1M+16K$77.13Jul 11, 2025
Garfield AlastairChief Scientific O…EXERCISEN/A4KJul 3, 2025
Garfield AlastairChief Scientific O…SELL$50K–$100K1K$64.81Jul 3, 2025
German Christopher PaulCorporate Controll…SELL$100K–$500K2K$67.19Jun 12, 2025
German Christopher PaulCorporate Controll…EXERCISE$15K–$50K1K$17.97Jun 12, 2025
Cramer Pamela J.CHROSELL$100K–$500K7K$68.05Jun 10, 2025
Cramer Pamela J.CHROEXERCISE$15K–$50K7K$6.80Jun 10, 2025
MCGIRR DAVID W JDirectorSELL$1M+65K$65.22Jun 5, 2025
MCGIRR DAVID W JDirectorEXERCISE$100K–$500K65K$4.59Jun 5, 2025
Meeker David PPresident and CEOSELL$1M+44K$65.05Jun 5, 2025
Meeker David PPresident and CEOEXERCISE$100K–$500K44K$4.59Jun 5, 2025
Smith Hunter CCFOSELL$1M+23K$61.41Jun 3, 2025
Smith Hunter CCFOEXERCISE$100K–$500K23K$6.88Jun 3, 2025
Cramer Pamela J.CHROSELL$100K–$500K7K$65.09May 1, 2025
Cramer Pamela J.CHROEXERCISE$15K–$50K7K$6.80May 1, 2025
Mazabraud YannEVPSELL$100K–$500K7K$65.08May 1, 2025
Cramer Pamela J.CHROEXERCISE$100K–$500K21K$13.43Apr 10, 2025
Cramer Pamela J.CHROSELL$1M+21K$60.14Apr 10, 2025
Mazabraud YannEVPSELL$1M+18K$60.99Apr 10, 2025
German Christopher PaulCorporate Controll…SELL$15K–$50K344$54.23Mar 24, 2025
German Christopher PaulCorporate Controll…EXERCISEN/A1KMar 24, 2025
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

RA Capital Management, L.P.

SC 13G/A · Feb 17, 2026

9.9%

6.7M shares

PRIMECAP MANAGEMENT CO/CA/

SC 13G/A · Feb 12, 2026

5.2%

3.5M shares

The Vanguard Group

SC 13G/A · Jan 30, 2026

9.3%

6.2M shares

PRIMECAP MANAGEMENT CO/CA/

SC 13G/A · Nov 14, 2025

6.4%

4.3M shares

The Vanguard Group

SC 13G/A · Oct 30, 2025

7.5%

5.0M shares

RA Capital Management, L.P.

SC 13G/A · Aug 14, 2025

8.7%

5.6M shares

PRIMECAP MANAGEMENT CO/CA/

SC 13G/A · Aug 14, 2025

7.7%

4.9M shares

Perceptive Advisors LLC

SC 13G/A · May 15, 2025

6.8%

4.4M shares

Baker Bros. Advisors LP

SC 13G/A · May 15, 2025

8.9%

5.6M shares

PRIMECAP MANAGEMENT CO/CA/

SC 13G/A · May 13, 2025

9.2%

5.8M shares

BlackRock, Inc.

SC 13G/A · Apr 24, 2025

6.9%

4.4M shares

PRIMECAP MANAGEMENT CO/CA/

SC 13G/A · Feb 13, 2025

10.7%

6.6M shares

THE GOLDMAN SACHS GROUP, INC.

SC 13G/A · Feb 10, 2025

3.0%

1.8M shares

Perceptive Advisors LLC

SC 13G · Nov 15, 2024

8.6%

5.4M shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2024

9.9%

6.1M shares

THE GOLDMAN SACHS GROUP, INC.

SC 13G/A · Nov 12, 2024

6.4%

3.9M shares

11.8%

7.2M shares

Perceptive Advisors LLC 2.

SC 13D/A · Apr 17, 2024

514.4M shares

Perceptive Advisors LLC 2.

SC 13D/A · Apr 3, 2024

326.9M shares

Perceptive Advisors LLC 2.

SC 13D · Mar 20, 2024

326.9M shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2024

9.0%

5.3M shares

Baker Bros. Advisors LP

SC 13G/A · Feb 14, 2024

10.8%

6.4M shares

The Vanguard Group - 23-1945930

SC 13G · Feb 13, 2024

5.5%

3.2M shares

Perceptive Advisors LLC

SC 13G · Feb 12, 2024

5.5%

3.3M shares

13.6%

8.1M shares

BlackRock, Inc.

SC 13G/A · Jan 24, 2024

10.7%

6.4M shares

Federated Hermes, Inc.

SC 13G/A · Sep 7, 2023

4.1%

2.3M shares

BlackRock, Inc.

SC 13G/A · Jul 7, 2023

11.0%

6.3M shares

New Enterprise Associates 13, L.P.

SC 13D/A · Mar 28, 2023

5.1%

2.9M shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2023

9.8%

5.5M shares

Baker Bros. Advisors LP

SC 13G/A · Feb 14, 2023

11.3%

6.4M shares

12.3%

6.9M shares

BlackRock, Inc.

SC 13G · Feb 3, 2023

6.6%

3.7M shares

Federated Hermes, Inc.

SC 13G/A · Feb 1, 2023

11.2%

6.3M shares

Baker Bros. Advisors LP

SC 13G/A · Oct 7, 2022

10.9%

6.1M shares

BlackRock, Inc.

SC 13G · Jul 8, 2022

2.3%

1.2M shares

10.1%

5.1M shares

Baker Bros. Advisors LP

SC 13G/A · Feb 14, 2022

7.7%

3.9M shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2022

9.7%

4.9M shares

5.6%

2.8M shares

Deerfield Mgmt, L.P.

SC 13G/A · Feb 11, 2022

3.1%

1.6M shares

6.2%

3.1M shares

12.4%

6.3M shares

THE GOLDMAN SACHS GROUP, INC.

SC 13G · Jan 24, 2022

6.1%

3.1M shares

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