Baker Bros. Advisors LP

Activist investor & 5%+ owner · SC 13D/13G filings

Total Filings

174

Stocks Covered

68

Latest Filing

Feb 17, 2026

Filings

GRAL

GRAIL, Inc.

SC 13G · Feb 17, 2026

5.3%

2.1M shares

ALKS

Alkermes plc.

SC 13G · Feb 17, 2026

6.1%

10.0M shares

KALA

KALA BIO, Inc.

SC 13G/A · Feb 17, 2026

10.0%

2.9M shares

RVMD

Revolution Medicines, Inc.

SC 13G/A · Feb 17, 2026

4.9%

9.5M shares

NRIX

Nurix Therapeutics, Inc.

SC 13G/A · Feb 17, 2026

7.2%

7.5M shares

STOK

Stoke Therapeutics, Inc.

SC 13G/A · Feb 17, 2026

5.8%

3.3M shares

IMTX

Immatics N.V.

SC 13G/A · Nov 14, 2025

9.9%

12.1M shares

CERS

Cerus Corporation

SC 13G/A · Nov 14, 2025

5.2%

10.0M shares

KALA

KALA BIO, Inc.

SC 13G · Oct 3, 2025

10.0%

745K shares

EWTX

Edgewise Therapeutics, Inc.

SC 13G/A · Aug 14, 2025

6.9%

7.3M shares

IMTX

Immatics N.V.

SC 13G/A · Aug 14, 2025

8.4%

10.2M shares

NGNE

Neurogene Inc.

SC 13G/A · Aug 14, 2025

7.0%

992K shares

RVMD

Revolution Medicines, Inc.

SC 13G · Aug 14, 2025

5.0%

9.4M shares

CERS

Cerus Corporation

SC 13G/A · Aug 14, 2025

6.7%

12.9M shares

CADL

Candel Therapeutics, Inc.

SC 13G/A · May 15, 2025

5.0%

2.5M shares

NGNE

Neurogene Inc.

SC 13G · May 15, 2025

9.9%

1.5M shares

RYTM

Rhythm Pharmaceuticals, Inc.

SC 13G/A · May 15, 2025

8.9%

5.6M shares

CELC

Celcuity Inc.

SC 13G/A · Apr 7, 2025

11.3%

4.3M shares

IMTX

Immatics N.V.

SC 13G/A · Feb 14, 2025

6.0%

7.3M shares

CELC

Celcuity Inc.

SC 13G/A · Feb 14, 2025

7.2%

2.7M shares

CADL

Candel Therapeutics, Inc.

SC 13G · Feb 14, 2025

6.8%

3.0M shares

BMEA

Biomea Fusion, Inc.

SC 13G/A · Feb 14, 2025

4.0%

1.5M shares

BCYC

Bicycle Therapeutics plc

SC 13D/A · Dec 17, 2024

22.9%

10.9M shares

ONC

BeiGene, Ltd.

SC 13D/A · Dec 11, 2024

9.0%

124.8M shares

SGMT

Sagimet Biosciences Inc.

SC 13G/A · Nov 14, 2024

5.0%

1.5M shares

CELC

Celcuity Inc.

SC 13G · Nov 14, 2024

5.1%

1.9M shares

STOK

Stoke Therapeutics, Inc.

SC 13G · Nov 14, 2024

8.3%

4.4M shares

ACHL

Achilles Therapeutics plc

SC 13G/A · Nov 14, 2024

0.0%

0 shares

NRIX

Nurix Therapeutics, Inc .

SC 13G/A · Nov 14, 2024

9.7%

6.8M shares

AVTE

Aerovate Therapeutics, Inc.

SC 13G/A · Nov 14, 2024

2.2%

629K shares

REPL

Replimune Group, Inc.

SC 13G/A · Nov 14, 2024

16.2%

11.0M shares

ATHA

Athira Pharma, Inc.

SC 13G/A · Nov 14, 2024

0.0%

0 shares

EWTX

Edgewise Therapeutics, Inc .

SC 13G · Nov 14, 2024

6.2%

5.8M shares

ABCL

AbCellera Biologics Inc.

SC 13G/A · Nov 14, 2024

9.3%

27.5M shares

TLIS

Talis Biomedical Corporation

SC 13D/A · Oct 10, 2024

65.6%

2.5M shares

KNSA

Kiniksa Pharmaceuticals International, plc (f/k/a Kiniksa Pharmaceuticals, Ltd.)**

SC 13D/A · Oct 8, 2024

7.6%

3.1M shares

KYMR

Kymera Therapeutics, Inc.

SC 13D/A · Aug 22, 2024

9.3%

6.0M shares

KALA

KALA BIO, Inc.

SC 13D · Jun 28, 2024

20.0%

891K shares

TRDA

Entrada Therapeutics, Inc.

SC 13D/A · Jun 26, 2024

13.2%

4.9M shares

HOOK

HOOKIPA Pharma Inc.

SC 13D · Jun 14, 2024

10.0%

9.8M shares

INCY

Incyte Corporation

SC 13D/A · Jun 14, 2024

16.1%

30.8M shares

BCYC

Bicycle Therapeutics plc

SC 13D/A · May 28, 2024

19.9%

9.4M shares

INCY

Incyte Corporation

SC 13D/A · May 13, 2024

16.1%

36.3M shares

INCY

Incyte Corporation

SC 13D/A · May 9, 2024

16.2%

36.3M shares

TCRX

TScan Therapeutics, Inc.

SC 13D/A · Apr 23, 2024

6.1%

2.8M shares

BCYC

Bicycle Therapeutics plc

SC 13D · Apr 18, 2024

19.9%

7.7M shares

KYMR

Kymera Therapeutics, Inc.

SC 13D · Apr 1, 2024

9.8%

6.0M shares

IGMS

IGM Biosciences, Inc.

SC 13D/A · Mar 28, 2024

12.4%

4.1M shares

MDGL

Madrigal Pharmaceuticals, Inc.

SC 13D/A · Mar 25, 2024

10.0%

2.1M shares

VTVT

vTv Therapeutics Inc.

SC 13D · Mar 5, 2024

5.0%

123K shares