EWTX

Edgewise Therapeutics, Inc.

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

93

Buys

11

Sells

43

Largest Trade

N/A

Insiders

12

Institutional Funds

145

Inst. Value

$1M+

Activist Filings

47

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Edris BadreddinDirectorSELL$1M+115K$29.44Jan 23, 2026
Edris BadreddinDirectorEXERCISE$100K–$500K115K$1.47Jan 23, 2026
Russell Alan JChief Scientific O…SELL$1M+100K$21.12Nov 13, 2025
Russell Alan JChief Scientific O…EXERCISE$15K–$50K100K$0.18Nov 13, 2025
Fox Jonathan CDirectorBUY$100K–$500K11K$18.64Nov 13, 2025
Russell Alan JChief Scientific O…EXERCISE$15K–$50K100K$0.18Aug 28, 2025
Russell Alan JChief Scientific O…SELL$1M+100K$14.60Aug 28, 2025
Russell Alan JChief Scientific O…EXERCISEN/A5KMay 8, 2025
Russell Alan JChief Scientific O…SELL$15K–$50K2K$16.45May 8, 2025
MOORE JOHN RGeneral CounselEXERCISEN/A5KMay 8, 2025
MOORE JOHN RGeneral CounselSELL$15K–$50K2K$16.45May 8, 2025
KOCH KEVINPresident and CEOSELL$50K–$100K4K$16.45May 8, 2025
KOCH KEVINPresident and CEOEXERCISEN/A10KMay 8, 2025
Donovan Joanne M.CMOSELL$50K–$100K5K$16.45May 8, 2025
Donovan Joanne M.CMOEXERCISEN/A10KMay 8, 2025
Derakhshan BehradChief Business Off…EXERCISEN/A5KMay 8, 2025
Derakhshan BehradChief Business Off…SELL$15K–$50K2K$16.45May 8, 2025
Carruthers R MichaelCFOSELL$15K–$50K1K$16.45May 8, 2025
Carruthers R MichaelCFOEXERCISEN/A5KMay 8, 2025
Thompson Peter A.DirectorBUY$1M+497K$20.13Apr 4, 2025
ORBIMED ADVISORS LLCDirectorBUY$1M+497K$20.13Apr 4, 2025
Donovan Joanne M.CMOSELL$500K+25K$27.63Jan 30, 2025
Donovan Joanne M.CMOEXERCISE$100K–$500K25K$7.08Jan 30, 2025
Russell Alan JChief Scientific O…SELL$1M+100K$27.37Dec 31, 2024
Russell Alan JChief Scientific O…EXERCISE$15K–$50K100K$0.18Dec 31, 2024
Semigran MarcChief Development …EXERCISE$100K–$500K30K$8.94Dec 27, 2024
Semigran MarcChief Development …SELL$500K+30K$29.69Dec 27, 2024
Russell Alan JChief Scientific O…SELL$1M+75K$28.27Sep 25, 2024
Russell Alan JChief Scientific O…EXERCISE$1K–$15K75K$0.18Sep 25, 2024
MOORE JOHN RGeneral CounselSELL$1M+71K$28.15Sep 25, 2024
MOORE JOHN RGeneral CounselEXERCISE$50K–$100K71K$0.71Sep 25, 2024
Donovan Joanne M.CMOSELL$100K–$500K7K$28.29Sep 25, 2024
Derakhshan BehradChief Business Off…EXERCISE$50K–$100K42K$1.93Sep 25, 2024
Derakhshan BehradChief Business Off…SELL$1M+42K$29.03Sep 25, 2024
Carruthers R MichaelCFOEXERCISE$100K–$500K96K$1.93Sep 25, 2024
Carruthers R MichaelCFOSELL$1M+125K$28.57Sep 25, 2024
MOORE JOHN RGeneral CounselSELL$15K–$50K2K$18.91May 3, 2024
MOORE JOHN RGeneral CounselEXERCISEN/A5KMay 3, 2024
Carruthers R MichaelCFOEXERCISEN/A5KMay 3, 2024
Carruthers R MichaelCFOSELL$15K–$50K2K$18.91May 3, 2024
Derakhshan BehradChief Business Off…SELL$15K–$50K2K$18.91May 3, 2024
Derakhshan BehradChief Business Off…EXERCISEN/A5KMay 3, 2024
Russell Alan JChief Scientific O…SELL$15K–$50K2K$18.91May 3, 2024
Russell Alan JChief Scientific O…EXERCISEN/A5KMay 3, 2024
Donovan Joanne M.CMOEXERCISEN/A10KMay 3, 2024
Donovan Joanne M.CMOSELL$50K–$100K4K$18.91May 3, 2024
KOCH KEVINPresident and CEOEXERCISEN/A10KMay 3, 2024
KOCH KEVINPresident and CEOSELL$50K–$100K3K$18.91May 3, 2024
MOORE JOHN RGeneral CounselEXERCISE$50K–$100K30K$1.93Feb 9, 2024
MOORE JOHN RGeneral CounselSELL$500K+30K$20.00Feb 9, 2024
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2025

9.9%

10.4M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Nov 14, 2025

4.7%

5.0M shares

Baker Bros. Advisors LP

SC 13G/A · Aug 14, 2025

6.9%

7.3M shares

Perceptive Advisors LLC

SC 13G/A · Aug 14, 2025

4.4%

4.6M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Aug 14, 2025

5.2%

5.5M shares

BlackRock, Inc.

SC 13G/A · Jul 17, 2025

5.5%

5.8M shares

Perceptive Advisors LLC

SC 13G/A · May 15, 2025

6.1%

6.4M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · May 14, 2025

5.6%

5.3M shares

ORBIMED ADVISORS LLC

SC 13D/A · May 12, 2025

14.5%

15.3M shares

Perceptive Advisors LLC

SC 13G · Feb 21, 2025

5.5%

5.2M shares

JANUS HENDERSON GROUP PLC

SC 13G · Feb 14, 2025

5.3%

5.0M shares

Paradigm BioCapital Advisors LP

SC 13G · Feb 3, 2025

5.0%

4.7M shares

EcoR1 Capital, LLC

SC 13G/A · Nov 14, 2024

1.3%

1.3M shares

Viking Global Investors LP

SC 13G/A · Nov 14, 2024

1.6%

1.5M shares

Baker Bros. Advisors LP

SC 13G · Nov 14, 2024

6.2%

5.8M shares

Deerfield Mgmt, L.P.

SC 13G/A · Nov 14, 2024

0.5%

479K shares

OrbiMed Advisors LLC

SC 13D/A · Nov 12, 2024

15.6%

14.8M shares

FMR LLC

SC 13G/A · Nov 12, 2024

0.7%

653K shares

BlackRock, Inc.

SC 13G · Nov 8, 2024

6.8%

6.4M shares

BlackRock, Inc.

SC 13G · Oct 22, 2024

6.8%

6.4M shares

Novo Holdings A/S 2.

SC 13D/A · Sep 24, 2024

5.9%

555.0M shares

FMR LLC

SC 13G/A · Jul 10, 2024

5.1%

4.8M shares

Viking Global Investors LP

SC 13G/A · Feb 14, 2024

9.7%

6.2M shares

Deep Track Capital, LP

SC 13G/A · Feb 14, 2024

4.0%

2.5M shares

BlackRock, Inc.

SC 13G · Feb 2, 2024

5.2%

3.3M shares

Deerfield Mgmt, L.P.

SC 13G/A · Feb 1, 2024

0.6%

545K shares

RA Capital Management, L.P.

SC 13G · Jan 29, 2024

9.6%

8.9M shares

Novo Holdings A/S 2.

SC 13D/A · Jan 25, 2024

7.4%

634.4M shares

OrbiMed Advisors LLC

SC 13D/A · Jan 25, 2024

17.3%

14.8M shares

Novo Holdings A/S

SC 13D/A · Jun 28, 2023

9.6%

6.1M shares

3.3%

2.1M shares

Viking Global Investors LP

SC 13G/A · Feb 14, 2023

7.0%

4.4M shares

Citadel Advisors LLC

SC 13G/A · Feb 14, 2023

4.2%

6 shares

Deerfield Mgmt IV, L.P.

SC 13G/A · Feb 10, 2023

6.2%

3.9M shares

0.0%

0 shares

FMR LLC

SC 13G/A · Oct 11, 2022

12.6%

8.0M shares

Novo Holdings A/S

SC 13D/A · Sep 30, 2022

9.6%

6.1M shares

EcoR1 Capital, LLC

SC 13G · Sep 26, 2022

5.5%

3.5M shares

Deep Track Capital, LP

SC 13G · Sep 23, 2022

5.3%

3.4M shares

OrbiMed Advisors LLC

SC 13D/A · Sep 16, 2022

23.3%

14.3M shares

Novo Holdings A/S

SC 13D/A · Sep 16, 2022

9.6%

6.1M shares

RA Capital Management, L.P.

SC 13G/A · Aug 15, 2022

0.0%

0 shares

Viking Global Investors LP

SC 13G/A · Feb 14, 2022

5.5%

2.7M shares

RA Capital Management, L.P.

SC 13G · Feb 14, 2022

5.3%

2.6M shares

5.5%

2.7M shares

Citadel Advisors LLC

SC 13G · Jan 13, 2022

5.0%

6 shares

Citadel Advisors LLC

SC 13G/A · Jan 13, 2022

4.8%

6 shares

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