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Paradigm BioCapital Advisors LP

Activist investor & 5%+ owner · SC 13D/13G filings

Total Filings

39

Stocks Covered

22

Latest Filing

Feb 24, 2026

Filings

EyePoint, Inc.

SC 13G · Feb 24, 2026

5.1%

4.2M shares

Erasca, Inc.

SC 13G · Jan 14, 2026

5.3%

15.2M shares

Lexeo Therapeutics, Inc.

SC 13G · Nov 20, 2025

5.0%

3.7M shares

VOR Biopharma Inc.

SC 13G · Nov 18, 2025

8.6%

1.8M shares

Cogent Biosciences, Inc.

SC 13G/A · Nov 14, 2025

2.3%

3.2M shares

Agios Pharmaceuticals, Inc.

SC 13G/A · Nov 14, 2025

4.9%

2.9M shares

Cidara Therapeutics, Inc.

SC 13G/A · Nov 14, 2025

3.3%

961K shares

LENZ Therapeutics, Inc.

SC 13G/A · Nov 14, 2025

3.8%

1.1M shares

Merus N.V.

SC 13G/A · Nov 14, 2025

6.2%

4.7M shares

UroGen Pharma Ltd.

SC 13G/A · Nov 14, 2025

9.0%

4.2M shares

Y-mAbs Therapeutics, Inc.

SC 13G/A · Nov 14, 2025

0.0%

0 shares

Agios Pharmaceuticals, Inc.

SC 13G · Aug 28, 2025

5.2%

3.0M shares

Cogent Biosciences, Inc.

SC 13G/A · Aug 14, 2025

9.1%

10.4M shares

Janux Therapeutics, Inc.

SC 13G/A · Aug 14, 2025

4.9%

2.9M shares

UroGen Pharma Ltd.

SC 13G · Aug 12, 2025

5.0%

2.3M shares

Cidara Therapeutics, Inc.

SC 13G · Jul 30, 2025

5.6%

1.1M shares

Disc Medicine, Inc.

SC 13G/A · May 15, 2025

3.5%

1.2M shares

Pliant Therapeutics, Inc.

SC 13G/A · May 15, 2025

0.0%

0 shares

Cogent Biosciences, Inc.

SC 13G/A · May 15, 2025

7.9%

9.0M shares

Merus N.V.

SC 13G · Apr 10, 2025

5.1%

3.6M shares

LENZ Therapeutics, Inc.

SC 13G · Mar 27, 2025

5.2%

1.4M shares

Olema Pharmaceuticals, Inc.

SC 13G/A · Feb 14, 2025

10.0%

7.4M shares

Kura Oncology, Inc.

SC 13G/A · Feb 14, 2025

0.0%

0 shares

Janux Therapeutics, Inc.

SC 13G/A · Feb 14, 2025

6.0%

3.5M shares

Cogent Biosciences, Inc.

SC 13G · Feb 12, 2025

5.0%

5.6M shares

Edgewise Therapeutics, Inc.

SC 13G · Feb 3, 2025

5.0%

4.7M shares

Tarsus Pharmaceuticals, Inc.

SC 13G/A · Nov 14, 2024

6.4%

2.4M shares

COMPASS Pathways plc

SC 13G/A · Nov 14, 2024

3.3%

2.3M shares

Olema Pharmaceuticals, Inc.

SC 13G/A · Nov 14, 2024

9.6%

5.5M shares

Vor Biopharma Inc.

SC 13G/A · Nov 14, 2024

0.0%

0 shares

Viridian Therapeutics, Inc.

SC 13G/A · Nov 14, 2024

4.6%

3.5M shares

Bicycle Therapeutics plc

SC 13G/A · Nov 14, 2024

0.0%

0 shares

Autolus Therapeutics plc

SC 13G/A · Nov 14, 2024

0.0%

0 shares

Kura Oncology, Inc.

SC 13G/A · Nov 14, 2024

5.7%

4.3M shares

Olema Pharmaceuticals, Inc.

SC 13G/A · Feb 14, 2024

14.3%

7.9M shares

Tarsus Pharmaceuticals, Inc.

SC 13G · Jan 22, 2024

5.8%

1.9M shares

Olema Pharmaceuticals, Inc.

SC 13G/A · Sep 13, 2023

14.3%

7.8M shares

Olema Pharmaceuticals, Inc.

SC 13G · Apr 10, 2023

6.2%

2.5M shares

Viridian Therapeutics Inc.

SC 13G · Feb 14, 2022

5.6%

1.2M shares