IRON

Disc Medicine, Inc.

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

100

Buys

6

Sells

69

Largest Trade

$1M+

Insiders

15

Institutional Funds

151

Inst. Value

$1M+

Activist Filings

48

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Savage William JacobChief Medical Offi…SELL$100K–$500K7K$65.88Mar 4, 2026
Franchi Jean M.CFOSELL$15K–$50K353$69.06Feb 27, 2026
Khara RahulChief Legal OfficerSELL$100K–$500K3K$62.86Feb 18, 2026
Stephenson PamelaChief Commercial O…SELL$100K–$500K6K$62.86Feb 18, 2026
Savage William JacobChief Medical Offi…SELL$100K–$500K3K$62.86Feb 18, 2026
Yu Jonathan Yen-WenCOOSELL$100K–$500K3K$62.86Feb 18, 2026
Quisel John DCEOSELL$500K+13K$62.86Feb 18, 2026
Khara RahulChief Legal OfficerSELL$50K–$100K1K$69.74Jan 21, 2026
Khara RahulChief Legal OfficerEXERCISE$1K–$15K1K$13.50Jan 21, 2026
Khara RahulChief Legal OfficerEXERCISE$50K–$100K7K$13.50Jan 6, 2026
Khara RahulChief Legal OfficerSELL$500K+7K$78.69Jan 6, 2026
Bitterman KevinDirectorSELL$50K–$100K754$91.47Dec 18, 2025
Bitterman KevinDirectorEXERCISE$50K–$100K7K$13.50Dec 17, 2025
Bitterman KevinDirectorSELL$1M+184K$91.56Dec 17, 2025
Savage William JacobChief Medical Offi…SELL$1M+13K$91.22Dec 17, 2025
Quisel John DCEOSELL$1M+40K$93.05Dec 15, 2025
Quisel John DCEOEXERCISE$100K–$500K40K$9.86Dec 15, 2025
Yu Jonathan Yen-WenCOOSELL$1M+30K$84.70Nov 14, 2025
Yu Jonathan Yen-WenCOOEXERCISE$50K–$100K30K$2.65Nov 14, 2025
AI DMI LLC10% OwnerSELL$1M+744K$80.47Oct 24, 2025
Bitterman KevinDirectorSELL$100K–$500K2K$61.03Aug 26, 2025
Bitterman KevinDirectorSELL$500K+8K$61.04Aug 1, 2025
Bitterman KevinDirectorSELL$1M+43K$61.03Jul 25, 2025
Bitterman KevinDirectorSELL$15K–$50K664$61.13Jul 22, 2025
Franchi Jean M.CFOSELL$100K–$500K2K$59.00Jul 18, 2025
Franchi Jean M.CFOSELL$100K–$500K2K$57.50Jul 15, 2025
Quisel John DCEOEXERCISE$100K–$500K35K$9.86Jul 11, 2025
Quisel John DCEOSELL$1M+35K$55.33Jul 11, 2025
Quisel John DCEOEXERCISE$50K–$100K5K$9.86Jul 9, 2025
Quisel John DCEOSELL$100K–$500K5K$55.09Jul 9, 2025
Franchi Jean M.CFOSELL$100K–$500K2K$52.26Jun 18, 2025
Savage William JacobChief Medical Offi…SELL$100K–$500K3K$50.00Jun 10, 2025
Savage William JacobChief Medical Offi…SELL$100K–$500K7K$50.04May 22, 2025
Savage William JacobChief Medical Offi…SELL$100K–$500K2K$50.17May 7, 2025
Ashiya MonaDirectorSELL$100K–$500K6K$54.11Mar 26, 2025
ORBIMED ADVISORS LLCDirectorSELL$100K–$500K6K$54.11Mar 26, 2025
Ashiya MonaDirectorSELL$1M+52K$54.02Mar 22, 2025
ORBIMED ADVISORS LLCDirectorSELL$1M+52K$54.02Mar 22, 2025
Ashiya MonaDirectorSELL$1M+312K$54.31Mar 13, 2025
ORBIMED ADVISORS LLCDirectorSELL$1M+312K$54.31Mar 13, 2025
Stephenson PamelaChief Commercial O…SELL$100K–$500K3K$54.58Feb 21, 2025
Khara RahulChief Legal OfficerSELL$50K–$100K1K$54.58Feb 21, 2025
Savage William JacobChief Medical Offi…SELL$50K–$100K2K$54.58Feb 21, 2025
Yu Jonathan Yen-WenCOOSELL$50K–$100K2K$54.58Feb 21, 2025
Franchi Jean M.CFOSELL$100K–$500K3K$54.58Feb 21, 2025
Quisel John DCEOSELL$100K–$500K6K$54.58Feb 21, 2025
Khara RahulChief Legal OfficerEXERCISE$100K–$500K8K$14.69Jan 6, 2025
Khara RahulChief Legal OfficerSELL$100K–$500K8K$62.75Jan 6, 2025
Quisel John DCEOEXERCISE$100K–$500K23K$6.01Jan 3, 2025
Quisel John DCEOSELL$500K+13K$61.95Jan 3, 2025
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

RA Capital Management, L.P.

SC 13G · Jan 7, 2026

5.9%

2.2M shares

Atlas Venture Fund X, L.P.

SC 13D/A · Dec 18, 2025

2.2%

813K shares

FMR LLC

SC 13G/A · Nov 5, 2025

14.1%

4.9M shares

AI DMI LLC

SC 13D/A · Oct 23, 2025

8.0%

3.0M shares

Atlas Venture Fund X, L.P.

SC 13D/A · Aug 15, 2025

3.1%

1.1M shares

3.0%

1.0M shares

Wellington Management Group LLP

SC 13G/A · Aug 12, 2025

4.1%

1.4M shares

FMR LLC

SC 13G/A · Aug 7, 2025

12.2%

4.2M shares

Paradigm BioCapital Advisors LP

SC 13G/A · May 15, 2025

3.5%

1.2M shares

Wellington Management Group LLP

SC 13G · May 12, 2025

6.8%

2.3M shares

FMR LLC

SC 13G/A · May 12, 2025

9.3%

3.2M shares

ORBIMED ADVISORS LLC

SC 13D/A · Mar 12, 2025

4.5%

1.6M shares

AI DMI LLC

SC 13D/A · Mar 3, 2025

10.8%

3.8M shares

3.3%

984K shares

FMR LLC

SC 13G · Feb 12, 2025

6.3%

1.9M shares

Wellington Management Group LLP

SC 13G/A · Feb 10, 2025

4.7%

1.4M shares

6.0%

1.8M shares

Disc Medicine, Inc. (Subject)

SC 13G/A · Nov 14, 2024

0.0%

0 shares

BlackRock, Inc.

SC 13G · Nov 8, 2024

6.2%

1.9M shares

Wellington Management Group LLP

SC 13G · Nov 8, 2024

6.2%

1.8M shares

BlackRock, Inc.

SC 13G · Oct 24, 2024

6.2%

1.9M shares

3.7%

1.1M shares

OrbiMed Advisors LLC

SC 13D/A · Jun 20, 2024

6.0%

1.8M shares

AI DMI LLC 2

SC 13D/A · Jun 20, 2024

12.6%

3.8M shares

Disc Medicine, Inc. (Subject)

SC 13G/A · Feb 14, 2024

0.0%

0 shares

5.5%

1.3M shares

ATLAS VENTURE FUND X, L.P.

SC 13D/A · Jan 25, 2024

5.8%

1.4M shares

OrbiMed Advisors LLC

SC 13D/A · Dec 15, 2023

7.1%

1.7M shares

AI DMI LLC

SC 13D/A · Nov 13, 2023

13.7%

3.3M shares

SC 13G · Sep 25, 2023

0.0%

0 shares

ATLAS VENTURE FUND X, L.P.

SC 13D/A · Sep 21, 2023

7.0%

1.6M shares

Adage Capital Partners, L.P.

SC 13G · Jun 30, 2023

5.2%

1.2M shares

Novo Holdings A/S

SC 13G/A · Jun 28, 2023

4.8%

1.1M shares

OrbiMed Advisors LLC

SC 13D/A · Jun 21, 2023

10.2%

2.3M shares

AI DMI LLC

SC 13D/A · Jun 20, 2023

14.9%

3.3M shares

10.0%

2.0M shares

AI DMI LLC

SC 13D/A · Feb 17, 2023

16.6%

3.1M shares

Adage Capital Partners, L.P.

SC 13D/A · Feb 16, 2023

1.9%

350K shares

Lightstone Ventures, L.P.

SC 13D/A · Feb 14, 2023

1.6%

280K shares

ATLAS VENTURE FUND X, L.P.

SC 13D/A · Feb 14, 2023

12.9%

2.2M shares

Suvretta Capital Management, LLC

SC 13G/A · Feb 13, 2023

0.0%

0 shares

FMR LLC

SC 13G · Feb 10, 2023

12.7%

2.1M shares

Franklin Resources, Inc.

SC 13G/A · Jan 31, 2023

0.0%

0 shares

AI DMI LLC

SC 13D · Jan 9, 2023

16.0%

2.7M shares

BML Investment Partners, L.P.

SC 13G · Jan 9, 2023

3.0%

500K shares

FS Development Holdings, LLC

SC 13D/A · Jan 4, 2023

2.9%

487K shares

OrbiMed Advisors LLC

SC 13D/A · Jan 3, 2023

12.8%

2.2M shares

Novo Holdings A/S

SC 13G · Jan 3, 2023

13.8%

2.3M shares

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