EWTX

Edgewise Therapeutics, Inc.

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

93

Buys

11

Sells

43

Largest Trade

N/A

Insiders

12

Institutional Funds

145

Inst. Value

$1M+

Activist Filings

47

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Derakhshan BehradChief Business Off…SELL$100K–$500K10K$20.03Feb 9, 2024
Derakhshan BehradChief Business Off…EXERCISE$15K–$50K10K$1.93Feb 9, 2024
Carruthers R MichaelCFOSELL$1M+90K$15.78Jan 25, 2024
Carruthers R MichaelCFOEXERCISE$100K–$500K90K$1.93Jan 25, 2024
Thompson Peter A.DirectorBUY$1M+455K$11.00Jan 25, 2024
ORBIMED ADVISORS LLCDirectorBUY$1M+455K$11.00Jan 25, 2024
Fox Jonathan CDirectorBUY$100K–$500K11K$9.30Dec 28, 2023
MOORE JOHN RGeneral CounselSELL$50K–$100K8K$10.50Dec 28, 2023
Russell Alan JChief Scientific O…SELL$1M+173K$9.33Dec 28, 2023
Derakhshan BehradChief Business Off…EXERCISEN/A5KMay 3, 2023
Derakhshan BehradChief Business Off…SELL$15K–$50K2K$8.90May 3, 2023
MOORE JOHN RGeneral CounselEXERCISEN/A5KMay 3, 2023
MOORE JOHN RGeneral CounselSELL$15K–$50K2K$8.90May 3, 2023
Carruthers R MichaelCFOSELL$1K–$15K1K$8.90May 3, 2023
Carruthers R MichaelCFOEXERCISEN/A5KMay 3, 2023
Russell Alan JChief Scientific O…SELL$1K–$15K2K$8.90May 3, 2023
Russell Alan JChief Scientific O…EXERCISEN/A5KMay 3, 2023
Donovan Joanne M.CMOEXERCISEN/A10KMay 3, 2023
Donovan Joanne M.CMOSELL$15K–$50K3K$8.90May 3, 2023
KOCH KEVINPresident and CEOEXERCISEN/A10KMay 3, 2023
KOCH KEVINPresident and CEOSELL$15K–$50K3K$8.90May 3, 2023
MOORE JOHN RGeneral CounselEXERCISE$1K–$15K5K$1.93Oct 5, 2022
MOORE JOHN RGeneral CounselSELL$15K–$50K5K$9.76Oct 5, 2022
Thompson Peter A.DirectorBUY$1M+484K$10.32Sep 16, 2022
ORBIMED ADVISORS LLCDirectorBUY$1M+484K$10.32Sep 16, 2022
Novo Holdings A/S10% OwnerBUY$1M+484K$10.32Sep 16, 2022
MOORE JOHN RGeneral CounselSELL$50K–$100K5K$10.91Sep 8, 2022
MOORE JOHN RGeneral CounselEXERCISE$1K–$15K5K$1.93Sep 8, 2022
MOORE JOHN RGeneral CounselSELL$50K–$100K9K$9.31Aug 5, 2022
MOORE JOHN RGeneral CounselEXERCISE$1K–$15K9K$1.34Aug 5, 2022
MOORE JOHN RGeneral CounselSELL$50K–$100K9K$8.37Jul 7, 2022
MOORE JOHN RGeneral CounselEXERCISE$1K–$15K9K$1.34Jul 7, 2022
MOORE JOHN RGeneral CounselSELL$100K–$500K68K$6.83Jun 21, 2022
MOORE JOHN RGeneral CounselEXERCISE$100K–$500K68K$1.69Jun 21, 2022
MOORE JOHN RGeneral CounselSELL$100K–$500K26K$6.08Jun 15, 2022
MOORE JOHN RGeneral CounselEXERCISE$15K–$50K26K$0.74Jun 15, 2022
MOORE JOHN RGeneral CounselSELL$100K–$500K27K$6.44Jun 10, 2022
MOORE JOHN RGeneral CounselEXERCISE$15K–$50K27K$0.71Jun 10, 2022
MOORE JOHN RGeneral CounselEXERCISE$50K–$100K47K$1.49Jun 7, 2022
MOORE JOHN RGeneral CounselSELL$100K–$500K47K$6.26Jun 7, 2022
ORBIMED ADVISORS LLCDirectorBUY$500K+138K$7.21May 20, 2022
Thompson Peter A.DirectorBUY$500K+138K$7.21May 20, 2022
MOORE JOHN RGeneral CounselSELL$50K–$100K11K$7.42May 18, 2022
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2025

9.9%

10.4M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Nov 14, 2025

4.7%

5.0M shares

Baker Bros. Advisors LP

SC 13G/A · Aug 14, 2025

6.9%

7.3M shares

Perceptive Advisors LLC

SC 13G/A · Aug 14, 2025

4.4%

4.6M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Aug 14, 2025

5.2%

5.5M shares

BlackRock, Inc.

SC 13G/A · Jul 17, 2025

5.5%

5.8M shares

Perceptive Advisors LLC

SC 13G/A · May 15, 2025

6.1%

6.4M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · May 14, 2025

5.6%

5.3M shares

ORBIMED ADVISORS LLC

SC 13D/A · May 12, 2025

14.5%

15.3M shares

Perceptive Advisors LLC

SC 13G · Feb 21, 2025

5.5%

5.2M shares

JANUS HENDERSON GROUP PLC

SC 13G · Feb 14, 2025

5.3%

5.0M shares

Paradigm BioCapital Advisors LP

SC 13G · Feb 3, 2025

5.0%

4.7M shares

EcoR1 Capital, LLC

SC 13G/A · Nov 14, 2024

1.3%

1.3M shares

Viking Global Investors LP

SC 13G/A · Nov 14, 2024

1.6%

1.5M shares

Baker Bros. Advisors LP

SC 13G · Nov 14, 2024

6.2%

5.8M shares

Deerfield Mgmt, L.P.

SC 13G/A · Nov 14, 2024

0.5%

479K shares

OrbiMed Advisors LLC

SC 13D/A · Nov 12, 2024

15.6%

14.8M shares

FMR LLC

SC 13G/A · Nov 12, 2024

0.7%

653K shares

BlackRock, Inc.

SC 13G · Nov 8, 2024

6.8%

6.4M shares

BlackRock, Inc.

SC 13G · Oct 22, 2024

6.8%

6.4M shares

Novo Holdings A/S 2.

SC 13D/A · Sep 24, 2024

5.9%

555.0M shares

FMR LLC

SC 13G/A · Jul 10, 2024

5.1%

4.8M shares

Viking Global Investors LP

SC 13G/A · Feb 14, 2024

9.7%

6.2M shares

Deep Track Capital, LP

SC 13G/A · Feb 14, 2024

4.0%

2.5M shares

BlackRock, Inc.

SC 13G · Feb 2, 2024

5.2%

3.3M shares

Deerfield Mgmt, L.P.

SC 13G/A · Feb 1, 2024

0.6%

545K shares

RA Capital Management, L.P.

SC 13G · Jan 29, 2024

9.6%

8.9M shares

Novo Holdings A/S 2.

SC 13D/A · Jan 25, 2024

7.4%

634.4M shares

OrbiMed Advisors LLC

SC 13D/A · Jan 25, 2024

17.3%

14.8M shares

Novo Holdings A/S

SC 13D/A · Jun 28, 2023

9.6%

6.1M shares

3.3%

2.1M shares

Viking Global Investors LP

SC 13G/A · Feb 14, 2023

7.0%

4.4M shares

Citadel Advisors LLC

SC 13G/A · Feb 14, 2023

4.2%

6 shares

Deerfield Mgmt IV, L.P.

SC 13G/A · Feb 10, 2023

6.2%

3.9M shares

0.0%

0 shares

FMR LLC

SC 13G/A · Oct 11, 2022

12.6%

8.0M shares

Novo Holdings A/S

SC 13D/A · Sep 30, 2022

9.6%

6.1M shares

EcoR1 Capital, LLC

SC 13G · Sep 26, 2022

5.5%

3.5M shares

Deep Track Capital, LP

SC 13G · Sep 23, 2022

5.3%

3.4M shares

OrbiMed Advisors LLC

SC 13D/A · Sep 16, 2022

23.3%

14.3M shares

Novo Holdings A/S

SC 13D/A · Sep 16, 2022

9.6%

6.1M shares

RA Capital Management, L.P.

SC 13G/A · Aug 15, 2022

0.0%

0 shares

Viking Global Investors LP

SC 13G/A · Feb 14, 2022

5.5%

2.7M shares

RA Capital Management, L.P.

SC 13G · Feb 14, 2022

5.3%

2.6M shares

5.5%

2.7M shares

Citadel Advisors LLC

SC 13G · Jan 13, 2022

5.0%

6 shares

Citadel Advisors LLC

SC 13G/A · Jan 13, 2022

4.8%

6 shares

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