Edgewise Therapeutics, Inc.
Total Trades
93
Buys
11
Sells
43
Largest Trade
N/A
Insiders
12
Institutional Funds
145
Inst. Value
$1M+
Activist Filings
47
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Derakhshan Behrad | Chief Business Off… | SELL | $100K–$500K | 10K | $20.03 | Feb 9, 2024 |
| Derakhshan Behrad | Chief Business Off… | EXERCISE | $15K–$50K | 10K | $1.93 | Feb 9, 2024 |
| Carruthers R Michael | CFO | SELL | $1M+ | 90K | $15.78 | Jan 25, 2024 |
| Carruthers R Michael | CFO | EXERCISE | $100K–$500K | 90K | $1.93 | Jan 25, 2024 |
| Thompson Peter A. | Director | BUY | $1M+ | 455K | $11.00 | Jan 25, 2024 |
| ORBIMED ADVISORS LLC | Director | BUY | $1M+ | 455K | $11.00 | Jan 25, 2024 |
| Fox Jonathan C | Director | BUY | $100K–$500K | 11K | $9.30 | Dec 28, 2023 |
| MOORE JOHN R | General Counsel | SELL | $50K–$100K | 8K | $10.50 | Dec 28, 2023 |
| Russell Alan J | Chief Scientific O… | SELL | $1M+ | 173K | $9.33 | Dec 28, 2023 |
| Derakhshan Behrad | Chief Business Off… | EXERCISE | N/A | 5K | — | May 3, 2023 |
| Derakhshan Behrad | Chief Business Off… | SELL | $15K–$50K | 2K | $8.90 | May 3, 2023 |
| MOORE JOHN R | General Counsel | EXERCISE | N/A | 5K | — | May 3, 2023 |
| MOORE JOHN R | General Counsel | SELL | $15K–$50K | 2K | $8.90 | May 3, 2023 |
| Carruthers R Michael | CFO | SELL | $1K–$15K | 1K | $8.90 | May 3, 2023 |
| Carruthers R Michael | CFO | EXERCISE | N/A | 5K | — | May 3, 2023 |
| Russell Alan J | Chief Scientific O… | SELL | $1K–$15K | 2K | $8.90 | May 3, 2023 |
| Russell Alan J | Chief Scientific O… | EXERCISE | N/A | 5K | — | May 3, 2023 |
| Donovan Joanne M. | CMO | EXERCISE | N/A | 10K | — | May 3, 2023 |
| Donovan Joanne M. | CMO | SELL | $15K–$50K | 3K | $8.90 | May 3, 2023 |
| KOCH KEVIN | President and CEO | EXERCISE | N/A | 10K | — | May 3, 2023 |
| KOCH KEVIN | President and CEO | SELL | $15K–$50K | 3K | $8.90 | May 3, 2023 |
| MOORE JOHN R | General Counsel | EXERCISE | $1K–$15K | 5K | $1.93 | Oct 5, 2022 |
| MOORE JOHN R | General Counsel | SELL | $15K–$50K | 5K | $9.76 | Oct 5, 2022 |
| Thompson Peter A. | Director | BUY | $1M+ | 484K | $10.32 | Sep 16, 2022 |
| ORBIMED ADVISORS LLC | Director | BUY | $1M+ | 484K | $10.32 | Sep 16, 2022 |
| Novo Holdings A/S | 10% Owner | BUY | $1M+ | 484K | $10.32 | Sep 16, 2022 |
| MOORE JOHN R | General Counsel | SELL | $50K–$100K | 5K | $10.91 | Sep 8, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $1K–$15K | 5K | $1.93 | Sep 8, 2022 |
| MOORE JOHN R | General Counsel | SELL | $50K–$100K | 9K | $9.31 | Aug 5, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $1K–$15K | 9K | $1.34 | Aug 5, 2022 |
| MOORE JOHN R | General Counsel | SELL | $50K–$100K | 9K | $8.37 | Jul 7, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $1K–$15K | 9K | $1.34 | Jul 7, 2022 |
| MOORE JOHN R | General Counsel | SELL | $100K–$500K | 68K | $6.83 | Jun 21, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $100K–$500K | 68K | $1.69 | Jun 21, 2022 |
| MOORE JOHN R | General Counsel | SELL | $100K–$500K | 26K | $6.08 | Jun 15, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $15K–$50K | 26K | $0.74 | Jun 15, 2022 |
| MOORE JOHN R | General Counsel | SELL | $100K–$500K | 27K | $6.44 | Jun 10, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $15K–$50K | 27K | $0.71 | Jun 10, 2022 |
| MOORE JOHN R | General Counsel | EXERCISE | $50K–$100K | 47K | $1.49 | Jun 7, 2022 |
| MOORE JOHN R | General Counsel | SELL | $100K–$500K | 47K | $6.26 | Jun 7, 2022 |
| ORBIMED ADVISORS LLC | Director | BUY | $500K+ | 138K | $7.21 | May 20, 2022 |
| Thompson Peter A. | Director | BUY | $500K+ | 138K | $7.21 | May 20, 2022 |
| MOORE JOHN R | General Counsel | SELL | $50K–$100K | 11K | $7.42 | May 18, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 145 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| ORBIMED ADVISORS LLC | 15.5M | $1M+ | SH |
| RA CAPITAL MANAGEMENT, L.P. | 10.4M | $1M+ | SH |
| Novo Holdings A/S | 5.3M | $1M+ | SH |
| BRAIDWELL LP | 5.2M | $1M+ | SH |
| Siren, L.L.C. | 4.5M | $1M+ | SH |
| PERCEPTIVE ADVISORS LLC | 4.5M | $1M+ | SH |
| Cormorant Asset Management, LP | 3.3M | $1M+ | SH |
| MORGAN STANLEY | 2.1M | $1M+ | SH |
| STATE STREET CORP | 1.7M | $1M+ | SH |
| MPM BioImpact LLC | 1.7M | $1M+ | SH |
| First Light Asset Management, LLC | 1.6M | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 1.5M | $1M+ | SH |
| AMERICAN CENTURY COMPANIES INC | 1.2M | $1M+ | SH |
| DIMENSIONAL FUND ADVISORS LP | 1.1M | $1M+ | SH |
| ALLIANCEBERNSTEIN L.P. | 1.0M | $1M+ | SH |
| Soleus Capital Management, L.P. | 910K | $1M+ | SH |
| Aberdeen Group plc | 822K | $1M+ | SH |
| NORGES BANK | 751K | $1M+ | SH |
| VICTORY CAPITAL MANAGEMENT INC | 747K | $1M+ | SH |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 640K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G/A · Nov 14, 2025
9.9%
10.4M shares
SC 13G/A · Nov 14, 2025
4.7%
5.0M shares
SC 13G/A · Aug 14, 2025
6.9%
7.3M shares
SC 13G/A · Aug 14, 2025
4.4%
4.6M shares
SC 13G/A · Aug 14, 2025
5.2%
5.5M shares
SC 13G/A · Jul 17, 2025
5.5%
5.8M shares
SC 13G/A · May 15, 2025
6.1%
6.4M shares
SC 13G/A · May 14, 2025
5.6%
5.3M shares
SC 13D/A · May 12, 2025
14.5%
15.3M shares
SC 13G · Feb 21, 2025
5.5%
5.2M shares
SC 13G · Feb 14, 2025
5.3%
5.0M shares
Paradigm BioCapital Advisors LP
SC 13G · Feb 3, 2025
5.0%
4.7M shares
SC 13G/A · Nov 14, 2024
1.3%
1.3M shares
SC 13G/A · Nov 14, 2024
1.6%
1.5M shares
SC 13G · Nov 14, 2024
6.2%
5.8M shares
SC 13G/A · Nov 14, 2024
0.5%
479K shares
SC 13D/A · Nov 12, 2024
15.6%
14.8M shares
SC 13G/A · Nov 12, 2024
0.7%
653K shares
SC 13G · Nov 8, 2024
6.8%
6.4M shares
SC 13G · Oct 22, 2024
6.8%
6.4M shares
SC 13D/A · Sep 24, 2024
5.9%
555.0M shares
SC 13G/A · Jul 10, 2024
5.1%
4.8M shares
SC 13G/A · Feb 14, 2024
9.7%
6.2M shares
SC 13G/A · Feb 14, 2024
4.0%
2.5M shares
SC 13G · Feb 2, 2024
5.2%
3.3M shares
SC 13G/A · Feb 1, 2024
0.6%
545K shares
SC 13G · Jan 29, 2024
9.6%
8.9M shares
SC 13D/A · Jan 25, 2024
7.4%
634.4M shares
SC 13D/A · Jan 25, 2024
17.3%
14.8M shares
SC 13D/A · Jun 28, 2023
9.6%
6.1M shares
Cormorant Global Healthcare Master Fund, LP
SC 13G/A · Feb 14, 2023
3.3%
2.1M shares
SC 13G/A · Feb 14, 2023
7.0%
4.4M shares
SC 13G/A · Feb 14, 2023
4.2%
6 shares
SC 13G/A · Feb 10, 2023
6.2%
3.9M shares
U.S. Venture Partners XI, L.P. (“USVP XI”)
SC 13D/A · Feb 1, 2023
0.0%
0 shares
SC 13G/A · Oct 11, 2022
12.6%
8.0M shares
SC 13D/A · Sep 30, 2022
9.6%
6.1M shares
SC 13G · Sep 26, 2022
5.5%
3.5M shares
SC 13G · Sep 23, 2022
5.3%
3.4M shares
SC 13D/A · Sep 16, 2022
23.3%
14.3M shares
SC 13D/A · Sep 16, 2022
9.6%
6.1M shares
SC 13G/A · Aug 15, 2022
0.0%
0 shares
SC 13G/A · Feb 14, 2022
5.5%
2.7M shares
SC 13G · Feb 14, 2022
5.3%
2.6M shares
Cormorant Global Healthcare Master Fund, LP
SC 13G/A · Feb 14, 2022
5.5%
2.7M shares
SC 13G · Jan 13, 2022
5.0%
6 shares
SC 13G/A · Jan 13, 2022
4.8%
6 shares