MDGL

MADRIGAL PHARMACEUTICALS, INC.

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

91

Buys

4

Sells

53

Largest Trade

N/A

Insiders

14

Institutional Funds

313

Inst. Value

$1M+

Activist Filings

38

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Dier MardiEVP and CFOSELL$500K+1K$427.21Mar 2, 2026
Huntsman CaroleChief Commercial O…SELL$100K–$500K910$493.78Jan 26, 2026
Sibold William JohnPresident and CEOSELL$500K+2K$492.42Jan 26, 2026
Taub RebeccaDirectorSELL$100K–$500K647$492.42Jan 26, 2026
Kelley Shannon TGeneral CounselSELL$100K–$500K692$497.36Jan 20, 2026
Taub RebeccaDirectorSELL$1M+2K$490.77Jan 20, 2026
FRIEDMAN PAUL ADirectorSELL$100K–$500K280$551.24Jan 13, 2026
FRIEDMAN PAUL ADirectorEXERCISE$1K–$15K280$15.80Jan 13, 2026
FRIEDMAN PAUL ADirectorSELL$1M+25K$522.39Jan 13, 2026
FRIEDMAN PAUL ADirectorEXERCISE$100K–$500K25K$15.80Jan 13, 2026
Taub RebeccaDirectorSELL$100K–$500K240$550.33Jan 13, 2026
Taub RebeccaDirectorEXERCISE$1K–$15K240$15.80Jan 13, 2026
Taub RebeccaDirectorSELL$1M+18K$522.40Jan 13, 2026
Taub RebeccaDirectorEXERCISE$100K–$500K18K$15.80Jan 13, 2026
FRIEDMAN PAUL ADirectorSELL$1M+25K$552.18Dec 12, 2025
FRIEDMAN PAUL ADirectorEXERCISE$100K–$500K25K$15.80Dec 12, 2025
Taub RebeccaDirectorEXERCISE$100K–$500K19K$15.80Dec 12, 2025
Taub RebeccaDirectorSELL$1M+19K$552.15Dec 12, 2025
Sibold William JohnPresident and CEOEXERCISEN/A50KDec 4, 2025
Sibold William JohnPresident and CEOSELL$1M+2K$575.34Dec 4, 2025
Dier MardiEVP and CFOEXERCISE$1M+4K$251.63Dec 3, 2025
Dier MardiEVP and CFOSELL$1M+4K$578.34Dec 3, 2025
Huntsman CaroleChief Commercial O…SELL$1M+2K$553.11Nov 21, 2025
Levy Richard SDirectorEXERCISE$100K–$500K9K$13.78Nov 14, 2025
Levy Richard SDirectorSELL$1M+9K$520.96Nov 14, 2025
BATE KENNETHDirectorSELL$1M+17K$484.30Nov 7, 2025
BATE KENNETHDirectorEXERCISE$1M+17K$205.07Nov 7, 2025
Sibold William JohnPresident and CEOSELL$1M+7K$445.63Sep 10, 2025
Taub RebeccaDirectorEXERCISE$1K–$15K1K$9.45Jul 22, 2025
Taub RebeccaDirectorSELL$100K–$500K1K$350.00Jul 22, 2025
FRIEDMAN PAUL ADirectorSELL$100K–$500K1K$350.03Jul 22, 2025
FRIEDMAN PAUL ADirectorEXERCISE$1K–$15K1K$9.45Jul 22, 2025
FRIEDMAN PAUL ADirectorSELL$1M+29K$353.19Jul 18, 2025
FRIEDMAN PAUL ADirectorEXERCISE$100K–$500K29K$9.45Jul 18, 2025
Taub RebeccaDirectorEXERCISE$100K–$500K29K$9.45Jul 18, 2025
Taub RebeccaDirectorSELL$1M+29K$353.19Jul 18, 2025
CRAVES FRED BDirectorSELL$1M+15K$328.54Mar 14, 2025
CRAVES FRED BDirectorEXERCISE$1M+15K$82.90Mar 14, 2025
Dier MardiSVP and CFOSELL$50K–$100K258$323.04Mar 12, 2025
Daly James MDirectorSELL$1M+15K$347.45Feb 28, 2025
Daly James MDirectorEXERCISE$1M+15K$82.90Feb 28, 2025
BATE KENNETHDirectorEXERCISE$1M+20K$66.26Feb 28, 2025
BATE KENNETHDirectorSELL$1M+20K$356.44Feb 28, 2025
Huntsman CaroleChief Commercial O…SELL$100K–$500K347$335.24Jan 27, 2025
Sibold William JohnPresident and CEOSELL$500K+2K$335.24Jan 27, 2025
Taub RebeccaPres., R&D, and CMOSELL$100K–$500K648$335.24Jan 27, 2025
Waltermire Robert E.Senior VPSELL$15K–$50K103$335.24Jan 27, 2025
Kelley Shannon TGeneral CounselSELL$50K–$100K277$273.41Jan 18, 2025
Waltermire Robert E.Senior VPSELL$100K–$500K442$273.41Jan 18, 2025
Taub RebeccaPres., R&D, and CMOSELL$100K–$500K2K$273.41Jan 18, 2025
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

PAULSON & CO. INC.

SC 13G/A · Feb 17, 2026

7.5%

1.7M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Feb 17, 2026

7.0%

1.6M shares

Rebecca Taub, M.D.

SC 13D/A · Dec 12, 2025

7.8%

1.8M shares

Paul A Friedman, M.D.

SC 13D/A · Dec 12, 2025

7.8%

1.8M shares

Rebecca Taub, M.D.

SC 13D/A · Dec 12, 2025

7.8%

1.8M shares

Paul A Friedman, M.D.

SC 13D/A · Dec 12, 2025

7.8%

1.8M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Nov 14, 2025

8.3%

1.8M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Aug 14, 2025

9.9%

2.2M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · May 14, 2025

10.0%

2.2M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Feb 14, 2025

10.1%

2.2M shares

PAULSON & CO. INC.

SC 13G/A · Nov 14, 2024

9.4%

2.0M shares

RTW Investments, LP

SC 13G · Nov 14, 2024

9.2%

2.0M shares

Baker Bros. Advisors LP

SC 13D/A · Mar 25, 2024

10.0%

2.1M shares

PAULSON & CO. INC.

SC 13G/A · Feb 14, 2024

5.6%

1.1M shares

Armistice Capital, LLC

SC 13G/A · Feb 14, 2024

0.3%

50K shares

Avoro Capital Advisors LLC

SC 13G/A · Feb 14, 2024

9.9%

2.3M shares

14.7%

2.9M shares

The Vanguard Group - 23-1945930

SC 13G/A · Feb 13, 2024

8.0%

1.6M shares

BlackRock, Inc.

SC 13G/A · Jan 29, 2024

6.1%

1.2M shares

Fred B. Craves

SC 13D/A · Dec 13, 2023

2.9%

568K shares

Baker Bros. Advisors LP

SC 13D/A · Nov 21, 2023

10.0%

2.0M shares

PAULSON & CO. INC.

SC 13G · Nov 13, 2023

5.1%

1.0M shares

15.4%

3.0M shares

Baker Bros. Advisors LP

SC 13D/A · Oct 5, 2023

10.0%

2.0M shares

10.3%

1.9M shares

Baker Bros. Advisors LP

SC 13D/A · Aug 8, 2023

8.4%

1.5M shares

Baker Bros. Advisors LP

SC 13D · Jun 16, 2023

8.4%

1.5M shares

Baker Bros. Advisors LP

SC 13G/A · Feb 14, 2023

9.0%

1.5M shares

Armistice Capital, LLC

SC 13G/A · Feb 14, 2023

1.2%

208K shares

Avoro Capital Advisors LLC

SC 13G/A · Feb 14, 2023

9.7%

1.7M shares

Deep Track Capital, LP

SC 13G/A · Feb 14, 2023

0.0%

0 shares

BlackRock, Inc.

SC 13G/A · Feb 1, 2023

5.8%

987K shares

Deep Track Capital, LP

SC 13G · May 19, 2022

5.4%

918K shares

Armistice Capital, LLC

SC 13G · Feb 14, 2022

6.6%

1.1M shares

HealthCor Management, L.P.

SC 13G/A · Feb 14, 2022

0.0%

0 shares

Avoro Capital Advisors LLC

SC 13G/A · Feb 11, 2022

8.3%

1.4M shares

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