IONS

IONIS PHARMACEUTICALS INC

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

283

Buys

Sells

161

Largest Trade

N/A

Insiders

Institutional Funds

410

Inst. Value

$1M+

Activist Filings

Insider Trades

Insider	Title	Type	Value	Shares	Price	Date
Geary Richard S	EVP	GRANT	N/A	4K	—	Feb 7, 2023
Geary Richard S	EVP	SELL	$50K–$100K	2K	$40.66	Feb 7, 2023
Cadoret-Manier Onaiza	EVP	SELL	$50K–$100K	1K	$40.66	Feb 7, 2023
Cadoret-Manier Onaiza	EVP	GRANT	N/A	4K	—	Feb 7, 2023
BENNETT C FRANK	EVP	SELL	$50K–$100K	2K	$40.57	Feb 7, 2023
BENNETT C FRANK	EVP	GRANT	N/A	4K	—	Feb 7, 2023
O'NEIL PATRICK R.	EVP CLO & General …	SELL	$100K–$500K	9K	$39.56	Feb 2, 2023
Swayze Eric	EVP Research	EXERCISE	N/A	16K	—	Jan 20, 2023
Swayze Eric	EVP Research	SELL	$100K–$500K	6K	$39.74	Jan 20, 2023
Schneider Eugene	EVP	EXERCISE	N/A	13K	—	Jan 20, 2023
Schneider Eugene	EVP	SELL	$100K–$500K	5K	$39.57	Jan 20, 2023
O'NEIL PATRICK R.	EVP CLO & General …	EXERCISE	N/A	22K	—	Jan 20, 2023
O'NEIL PATRICK R.	EVP CLO & General …	SELL	$100K–$500K	8K	$39.49	Jan 20, 2023
Monia Brett P	CEO	EXERCISE	N/A	57K	—	Jan 20, 2023
Monia Brett P	CEO	SELL	$500K+	25K	$39.49	Jan 20, 2023
HOUGEN ELIZABETH L	EVP, Finance & CFO	SELL	$100K–$500K	8K	$39.70	Jan 20, 2023
HOUGEN ELIZABETH L	EVP, Finance & CFO	EXERCISE	N/A	23K	—	Jan 20, 2023
Geary Richard S	EVP	SELL	$100K–$500K	8K	$39.57	Jan 20, 2023
Geary Richard S	EVP	EXERCISE	N/A	22K	—	Jan 20, 2023
Cadoret-Manier Onaiza	EVP	SELL	$100K–$500K	4K	$39.55	Jan 20, 2023
Cadoret-Manier Onaiza	EVP	EXERCISE	N/A	10K	—	Jan 20, 2023
BENNETT C FRANK	EVP	SELL	$100K–$500K	7K	$38.89	Jan 20, 2023
BENNETT C FRANK	EVP	EXERCISE	N/A	19K	—	Jan 20, 2023
Baroldi Joseph	EVP	SELL	$1K–$15K	375	$39.79	Jan 20, 2023
Baroldi Joseph	EVP	EXERCISE	N/A	904	—	Jan 20, 2023
KLEIN JOSEPH III	Director	SELL	$50K–$100K	2K	$40.00	Jan 19, 2023
Swayze Eric	EVP Research	SELL	$15K–$50K	460	$44.55	Sep 12, 2022
Swayze Eric	EVP Research	SELL	<$1K	1	$45.20	Aug 9, 2022
KLEIN JOSEPH III	Director	SELL	$50K–$100K	1K	$38.24	Jul 19, 2022
KLEIN JOSEPH III	Director	EXERCISE	N/A	8K	—	Jul 19, 2022
Swayze Eric	EVP Research	SELL	$15K–$50K	378	$44.15	Apr 26, 2022
O'NEIL PATRICK R.	EVP CLO & General …	SELL	$100K–$500K	7K	$40.06	Apr 14, 2022
Monia Brett P	CEO	SELL	$1K–$15K	355	$37.49	Apr 5, 2022

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Institutional Ownership

13F filings as of Dec 31, 2025 · 410 funds holding

Fund	Shares	Value	Type
Capital World Investors	18.0M	$1M+	SH
STATE STREET CORP	4.0M	$1M+	SH
GEODE CAPITAL MANAGEMENT, LLC	2.8M	$1M+	SH
Tweedy, Browne Co LLC	2.5M	$1M+	SH
Deep Track Capital, LP	1.7M	$1M+	SH
AMERICAN CENTURY COMPANIES INC	1.6M	$1M+	SH
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1.5M	$1M+	SH
Pictet Asset Management Holding SA	1.4M	$1M+	SH
Connor, Clark & Lunn Investment Management Ltd.	1.1M	$1M+	SH
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	1.1M	$1M+	SH
BNP Paribas Asset Management Holding S.A.	955K	$1M+	SH
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	865K	$1M+	SH
NOMURA HOLDINGS INC	849K	$1M+	SH
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	809K	$1M+	SH
TD ASSET MANAGEMENT INC	773K	$1M+	SH
GW&K Investment Management, LLC	742K	$1M+	SH
Candriam S.C.A.	678K	$1M+	SH
VOLORIDGE INVESTMENT MANAGEMENT, LLC	585K	$1M+	SH
EVENTIDE ASSET MANAGEMENT, LLC	575K	$1M+	SH
GOLDMAN SACHS GROUP INC	553K	$1M+	SH