SLNO

SOLENO THERAPEUTICS INC

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

69

Buys

12

Sells

49

Largest Trade

N/A

Insiders

13

Institutional Funds

180

Inst. Value

$1M+

Activist Filings

50

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Hirano Patricia CSEE REMARKSSELL$100K–$500K4K$82.76Jul 3, 2025
Hirano Patricia CSEE REMARKSSELL$15K–$50K266$84.25Jun 26, 2025
Hirano Patricia CSEE REMARKSEXERCISE$1K–$15K266$44.25Jun 26, 2025
Hirano Patricia CSEE REMARKSSELL$100K–$500K4K$70.11Apr 2, 2025
Pauls MatthewDirectorEXERCISE$15K–$50K6K$4.60Mar 31, 2025
Pauls MatthewDirectorSELL$100K–$500K6K$71.55Mar 31, 2025
Yen KristenSEE REMARKSSELL$1M+96K$66.77Mar 31, 2025
Yen KristenSEE REMARKSEXERCISE$100K–$500K41K$4.97Mar 31, 2025
Manning MeredithChief Commercial O…SELL$1M+45K$67.28Mar 31, 2025
Manning MeredithChief Commercial O…EXERCISE$1M+37K$46.31Mar 31, 2025
Mackaness James HCHIEF FINANCIAL OF…EXERCISE$500K+70K$11.72Mar 31, 2025
Mackaness James HCHIEF FINANCIAL OF…SELL$1M+91K$69.44Mar 31, 2025
Huang Michael F.Sr. VP of Clinical…EXERCISE$100K–$500K10K$21.93Mar 31, 2025
Huang Michael F.Sr. VP of Clinical…SELL$1M+15K$69.51Mar 31, 2025
Hirano Patricia CSEE REMARKSEXERCISE$500K+75K$8.14Mar 31, 2025
Hirano Patricia CSEE REMARKSSELL$1M+156K$68.51Mar 31, 2025
Anish BhatnagarCHIEF EXECUTIVE OF…EXERCISE$1M+524K$12.17Mar 31, 2025
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$1M+699K$67.62Mar 31, 2025
Vivo Opportunity, LLC10% OwnerSELL$1M+1.8M$67.87Mar 28, 2025
Yen KristenSEE REMARKSSELL$100K–$500K5K$45.78Jan 7, 2025
Mackaness James HCHIEF FINANCIAL OF…SELL$100K–$500K8K$45.78Jan 7, 2025
Hirano Patricia CSEE REMARKSSELL$100K–$500K3K$45.78Jan 7, 2025
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$500K+21K$45.78Jan 7, 2025
Yen KristenSEE REMARKSSELL$100K–$500K3K$49.43Oct 3, 2024
Mackaness James HCHIEF FINANCIAL OF…SELL$100K–$500K8K$49.43Oct 3, 2024
Hirano Patricia CSEE REMARKSSELL$100K–$500K3K$49.43Oct 3, 2024
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$1M+22K$49.43Oct 3, 2024
Yen KristenSEE REMARKSSELL$500K+11K$47.43Aug 30, 2024
Mackaness James HCHIEF FINANCIAL OF…SELL$500K+14K$47.43Aug 30, 2024
Hirano Patricia CSEE REMARKSSELL$500K+11K$47.43Aug 30, 2024
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$1M+115K$47.43Aug 30, 2024
Vivo Opportunity, LLC10% OwnerSELL$1M+1.0M$48.01Aug 29, 2024
Yen KristenSEE REMARKSSELL$50K–$100K2K$41.54Jul 3, 2024
Mackaness James HCHIEF FINANCIAL OF…SELL$100K–$500K7K$41.54Jul 3, 2024
Hirano Patricia CSEE REMARKSSELL$50K–$100K2K$41.54Jul 3, 2024
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$500K+19K$41.54Jul 3, 2024
Vivo Opportunity, LLC10% OwnerSELL$1M+1.1M$46.95May 1, 2024
Yen KristenSEE REMARKSSELL$50K–$100K2K$41.34Apr 4, 2024
Mackaness James HCHIEF FINANCIAL OF…SELL$100K–$500K5K$41.34Apr 4, 2024
Hirano Patricia CSEE REMARKSSELL$50K–$100K2K$41.34Apr 4, 2024
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$500K+19K$41.34Apr 4, 2024
Yen KristenSEE REMARKSSELL$15K–$50K397$48.30Jan 29, 2024
Hirano Patricia CSEE REMARKSSELL$15K–$50K832$48.30Jan 29, 2024
Anish BhatnagarCHIEF EXECUTIVE OF…SELL$100K–$500K3K$48.30Jan 29, 2024
Yen KristenSee RemarksSELL$100K–$500K4K$28.65Dec 5, 2023
Mackaness James HCFOSELL$100K–$500K4K$28.65Dec 5, 2023
Hirano Patricia CSee RemarksSELL$100K–$500K4K$28.65Dec 5, 2023
Anish BhatnagarCEOSELL$500K+28K$28.65Dec 5, 2023
Yen KristenSee RemarksSELL$100K–$500K8K$27.49Dec 1, 2023
Mackaness James HCFOSELL$100K–$500K8K$27.49Dec 1, 2023
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Wellington Management Group LLP

SC 13G · Feb 10, 2026

6.2%

3.3M shares

Vivo Opportunity Fund Holdings, L.P.

SC 13G/A · Nov 14, 2025

4.2%

2.3M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Nov 14, 2025

11.4%

6.1M shares

Adage Capital Management, L.P.

SC 13G/A · Nov 13, 2025

2.6%

1.4M shares

The Vanguard Group

SC 13G · Oct 31, 2025

5.3%

2.8M shares

Nantahala Capital Management, LLC

SC 13G/A · Aug 14, 2025

2.0%

1.0M shares

T. Rowe Price Associates, Inc.

SC 13G/A · Aug 14, 2025

6.9%

3.5M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Aug 14, 2025

10.5%

5.3M shares

Avoro Capital Advisors LLC

SC 13G/A · Aug 14, 2025

4.1%

2.0M shares

Vivo Opportunity Fund Holdings, L.P.

SC 13G/A · Aug 13, 2025

7.4%

4.0M shares

Adage Capital Management, L.P.

SC 13G/A · Aug 12, 2025

7.1%

3.6M shares

FMR LLC

SC 13G/A · Aug 7, 2025

15.0%

7.8M shares

FMR LLC

SC 13G · Aug 6, 2025

6.6%

3.3M shares

BlackRock, Inc.

SC 13G · Jul 18, 2025

5.5%

2.8M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · May 14, 2025

11.2%

5.2M shares

T. Rowe Price Associates, Inc.

SC 13G · May 14, 2025

5.2%

2.4M shares

Adage Capital Management, L.P.

SC 13G/A · May 12, 2025

9.6%

4.4M shares

Nantahala Capital Management, LLC

SC 13G/A · Apr 30, 2025

5.6%

2.6M shares

9.7%

4.5M shares

Nantahala Capital Management, LLC

SC 13G/A · Feb 14, 2025

10.0%

4.3M shares

JANUS HENDERSON GROUP PLC

SC 13G/A · Feb 14, 2025

12.0%

5.2M shares

Adage Capital Management, L.P.

SC 13G/A · Feb 12, 2025

6.4%

2.8M shares

BlackRock, Inc.

SC 13G/A · Feb 5, 2025

4.7%

2.0M shares

Perceptive Advisors LLC 2.

SC 13D/A · Nov 20, 2024

177.1M shares

Nantahala Capital Management, LLC

SC 13G/A · Nov 14, 2024

10.0%

4.0M shares

Perceptive Advisors LLC 2.

SC 13D/A · Nov 14, 2024

345.5M shares

10.5%

4.1M shares

Avoro Capital Advisors LLC

SC 13G · Nov 14, 2024

5.6%

2.2M shares

Adage Capital Management, L.P.

SC 13G/A · Nov 12, 2024

8.6%

3.3M shares

BlackRock, Inc.

SC 13G · Oct 24, 2024

5.2%

2.0M shares

The Carlyle Group Inc. 2

SC 13D/A · Oct 21, 2024

5.0%

200.3M shares

The Carlyle Group Inc. 2

SC 13D/A · Oct 15, 2024

6.2%

246.8M shares

The Carlyle Group Inc. 2

SC 13D/A · Oct 10, 2024

8.1%

325.1M shares

10.1%

4.2M shares

The Carlyle Group Inc.

SC 13D/A · Sep 10, 2024

10.0%

4.0M shares

16.2%

6.3M shares

22.5%

7.3M shares

Nantahala Capital Management, LLC

SC 13G/A · Feb 14, 2024

9.9%

3.1M shares

Commodore Capital LP

SC 13G/A · Feb 14, 2024

2.3%

700K shares

8.3%

2.5M shares

Perceptive Advisors LLC 2.

SC 13D/A · Oct 23, 2023

307.5M shares

The Carlyle Group Inc. 2

SC 13D/A · Oct 16, 2023

10.0%

289.4M shares

Adage Capital Partners, L.P.

SC 13G · Oct 12, 2023

8.7%

1.3M shares

Commodore Capital LP

SC 13G · Oct 12, 2023

6.0%

886K shares

Vivo Opportunity Fund Holdings, L.P.

SC 13D/A · Oct 11, 2023

30.5%

8.4M shares

Fairmount Funds Management LLC

SC 13G · Oct 10, 2023

6.2%

950K shares

10.1%

1.5M shares

RA Capital Management, L.P.

SC 13G · Oct 5, 2023

4.6%

1.2M shares

The Carlyle Group Inc. 2

SC 13D/A · Oct 3, 2023

10.0%

156.7M shares

Perceptive Advisors LLC 2.

SC 13D/A · Sep 29, 2023

307.5M shares

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