PRTA

PROTHENA CORP PUBLIC LTD CO

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

177

Buys

3

Sells

88

Largest Trade

$1M+

Insiders

14

Institutional Funds

137

Inst. Value

$1M+

Activist Filings

40

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Nguyen TranChief Strategy Off…EXERCISE$50K–$100K10K$6.73Aug 27, 2022
Nguyen TranChief Strategy Off…SELL$100K–$500K10K$30.17Aug 27, 2022
Kinney Gene G.President and CEOEXERCISE$1K–$15K2K$6.41Aug 20, 2022
Kinney Gene G.President and CEOSELL$50K–$100K2K$32.03Aug 20, 2022
Kinney Gene G.President and CEOEXERCISE$100K–$500K35K$6.41Aug 13, 2022
Kinney Gene G.President and CEOSELL$1M+35K$32.15Aug 13, 2022
Kinney Gene G.President and CEOSELL$1M+42K$32.51Aug 6, 2022
Kinney Gene G.President and CEOEXERCISE$100K–$500K42K$6.41Aug 6, 2022
Garren HidekiChief Medical Offi…EXERCISE$50K–$100K4K$24.90Aug 4, 2022
Garren HidekiChief Medical Offi…SELL$100K–$500K4K$30.52Aug 4, 2022
Kinney Gene G.President and CEOEXERCISE$1K–$15K376$6.41Jul 30, 2022
Kinney Gene G.President and CEOSELL$1K–$15K376$32.00Jul 30, 2022
Nguyen TranChief Strategy Off…SELL$1M+70K$32.54Jul 23, 2022
Nguyen TranChief Strategy Off…EXERCISE$100K–$500K70K$6.73Jul 23, 2022
Cooke ShaneDirectorSELL$100K–$500K15K$32.90Jul 23, 2022
Cooke ShaneDirectorEXERCISE$50K–$100K15K$6.41Jul 23, 2022
Garren HidekiChief Medical Offi…SELL$100K–$500K8K$30.00Jul 9, 2022
Garren HidekiChief Medical Offi…EXERCISE$100K–$500K8K$24.90Jul 9, 2022
EcoR1 Capital, LLC10% OwnerSELL$1M+1.1M$29.02May 9, 2022
EcoR1 Capital, LLC10% OwnerBUY$1M+1.1M$29.02May 9, 2022
Cooke ShaneDirectorSELL$100K–$500K5K$35.08Apr 14, 2022
Cooke ShaneDirectorEXERCISE$15K–$50K5K$6.41Apr 14, 2022
COLLIER RICHARD TDirectorEXERCISE$15K–$50K5K$6.41Apr 8, 2022
COLLIER RICHARD TDirectorSELL$100K–$500K5K$39.41Apr 8, 2022
EcoR1 Capital, LLC10% OwnerBUY$1M+300K$37.50Jan 12, 2022
Selkoe Dennis J.DirectorSELL$100K–$500K5K$47.45Jan 6, 2022
Selkoe Dennis J.DirectorEXERCISE$15K–$50K5K$9.23Jan 6, 2022
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Rubric Capital Management LP

SC 13G · Feb 13, 2026

6.8%

3.7M shares

ADAR1 Capital Management, LLC

SC 13G/A · Nov 15, 2025

2.7%

1.5M shares

Fennell Todd W.

SC 13G/A · Nov 12, 2025

8.4%

4.5M shares

SCULLY WILLIAM P

SC 13G/A · Nov 12, 2025

9.8%

5.3M shares

BlackRock, Inc.

SC 13G/A · Oct 17, 2025

5.7%

3.1M shares

ADAR1 Capital Management, LLC

SC 13G · Aug 15, 2025

6.3%

3.4M shares

Logos Global Management LP

SC 13G/A · Aug 14, 2025

0.0%

0 shares

T. Rowe Price Associates, Inc.

SC 13G/A · Aug 14, 2025

0.1%

71K shares

SCULLY WILLIAM P

SC 13G/A · Aug 13, 2025

9.9%

5.4M shares

Fennell Todd W.

SC 13G/A · Aug 13, 2025

8.1%

4.4M shares

Wellington Management Group LLP

SC 13G/A · Jun 5, 2025

0.2%

108K shares

Logos Global Management LP

SC 13G · Jun 4, 2025

5.5%

3.0M shares

EcoR1 Capital, LLC

SC 13D/A · May 30, 2025

0.0%

0 shares

Fennell Todd W.

SC 13G/A · May 15, 2025

8.5%

4.6M shares

SCULLY WILLIAM P

SC 13G/A · May 14, 2025

10.4%

5.6M shares

EcoR1 Capital, LLC

SC 13D/A · May 6, 2025

9.9%

5.3M shares

SCULLY WILLIAM P

SC 13G/A · Feb 21, 2025

10.3%

5.6M shares

Fennell Todd W.

SC 13G/A · Feb 14, 2025

8.6%

4.6M shares

Wellington Management Group LLP

SC 13G/A · Feb 10, 2025

9.5%

5.1M shares

EcoR1 Capital, LLC

SC 13D/A · Jan 4, 2025

21.5%

11.6M shares

7.1%

3.8M shares

Todd W. Fennell

SC 13G/A · Nov 13, 2024

5.9%

3.2M shares

William P. Scully 2

SC 13G/A · Nov 13, 2024

7.5%

403.6M shares

Wellington Management Group LLP

SC 13G · Nov 8, 2024

7.8%

4.2M shares

Wellington Management Group LLP

SC 13G/A · Nov 7, 2024

10.8%

5.8M shares

STATE STREET CORPORATION 04-2456637

SC 13G/A · Oct 18, 2024

3.1%

1.7M shares

Todd W. Fennell

SC 13G · Feb 14, 2024

5.8%

3.1M shares

William P. Scully 2

SC 13G · Feb 14, 2024

6.5%

350.2M shares

7.9%

4.2M shares

Avidity Partners Management LP

SC 13G/A · Feb 14, 2024

0.0%

0 shares

FMR LLC

SC 13G/A · Mar 10, 2023

10.0%

5.3M shares

Avidity Partners Management LP

SC 13G/A · Feb 14, 2023

5.7%

3.0M shares

William P. Scully

SC 13G/A · Feb 14, 2023

4.8%

2.5M shares

6.3%

3.2M shares

6.4%

3.0M shares

William P. Scully

SC 13G · Jun 27, 2022

5.4%

2.5M shares

3.9%

1.8M shares

12.7%

5.9M shares

EcoR1 Capital, LLC

SC 13D/A · Jan 13, 2022

24.9%

11.6M shares

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