PRTA

PROTHENA CORP PUBLIC LTD CO

Pharmaceutical PreparationsNasdaqLarge accelerated filer

Total Trades

177

Buys

3

Sells

88

Largest Trade

$1M+

Insiders

14

Institutional Funds

137

Inst. Value

$1M+

Activist Filings

40

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Walker Karin LChief Accounting O…EXERCISE$50K–$100K5K$15.04Jun 20, 2023
Walker Karin LChief Accounting O…SELL$100K–$500K5K$68.90Jun 20, 2023
Garren HidekiChief Medical Offi…SELL$500K+7K$74.00Jun 16, 2023
Garren HidekiChief Medical Offi…EXERCISE$100K–$500K7K$24.90Jun 16, 2023
Smith Brandon S.COOSELL$100K–$500K5K$73.98Jun 15, 2023
Smith Brandon S.COOEXERCISE$50K–$100K5K$11.12Jun 15, 2023
Garren HidekiChief Medical Offi…EXERCISE$100K–$500K5K$24.90Jun 15, 2023
Garren HidekiChief Medical Offi…SELL$100K–$500K5K$74.22Jun 15, 2023
Zago Wagner M.Chief Scientific O…SELL$1M+19K$71.06Jun 8, 2023
Zago Wagner M.Chief Scientific O…EXERCISE$100K–$500K19K$26.09Jun 8, 2023
Karp Carol D.Chief Regulatory O…SELL$1M+20K$71.05Jun 8, 2023
Karp Carol D.Chief Regulatory O…EXERCISE$100K–$500K20K$13.19Jun 8, 2023
Malecek Michael JChief Legal OfficerSELL$100K–$500K5K$64.64Jun 1, 2023
Malecek Michael JChief Legal OfficerEXERCISE$50K–$100K5K$10.27Jun 1, 2023
Walker Karin LChief Accounting O…EXERCISE$50K–$100K5K$15.04May 20, 2023
Walker Karin LChief Accounting O…SELL$100K–$500K5K$74.00May 20, 2023
Kinney Gene G.President and CEOSELL$1M+45K$73.70May 18, 2023
Kinney Gene G.President and CEOEXERCISE$1M+45K$29.81May 18, 2023
Nguyen TranChief Strategy Off…SELL$1M+95K$73.99May 18, 2023
Nguyen TranChief Strategy Off…EXERCISE$1M+95K$26.15May 18, 2023
Selkoe Dennis J.DirectorEXERCISE$100K–$500K15K$18.07May 6, 2023
Selkoe Dennis J.DirectorSELL$500K+15K$57.00May 6, 2023
Malecek Michael JChief Legal OfficerEXERCISE$50K–$100K5K$10.27Apr 29, 2023
Malecek Michael JChief Legal OfficerSELL$100K–$500K5K$53.46Apr 29, 2023
Walker Karin LChief Accounting O…SELL$100K–$500K5K$52.90Apr 22, 2023
Walker Karin LChief Accounting O…EXERCISE$50K–$100K5K$15.04Apr 22, 2023
Malecek Michael JChief Legal OfficerEXERCISE$50K–$100K5K$10.27Apr 1, 2023
Malecek Michael JChief Legal OfficerSELL$100K–$500K5K$49.02Apr 1, 2023
Walker Karin LChief Accounting O…EXERCISE$50K–$100K5K$15.04Mar 23, 2023
Walker Karin LChief Accounting O…SELL$100K–$500K5K$47.72Mar 23, 2023
Walker Karin LChief Accounting O…SELL$500K+20K$48.42Mar 18, 2023
Walker Karin LChief Accounting O…EXERCISE$100K–$500K20K$15.04Mar 18, 2023
Nguyen TranChief Strategy Off…SELL$100K–$500K10K$48.43Mar 18, 2023
Nguyen TranChief Strategy Off…EXERCISE$50K–$100K10K$6.73Mar 18, 2023
Malecek Michael JChief Legal OfficerEXERCISE$100K–$500K15K$10.27Mar 18, 2023
Malecek Michael JChief Legal OfficerSELL$500K+15K$48.44Mar 18, 2023
Garren HidekiChief Medical Offi…SELL$500K+12K$48.41Mar 18, 2023
Garren HidekiChief Medical Offi…EXERCISE$100K–$500K12K$24.90Mar 18, 2023
Nguyen TranChief Strategy Off…SELL$500K+10K$53.34Feb 18, 2023
Nguyen TranChief Strategy Off…EXERCISE$50K–$100K10K$6.73Feb 18, 2023
Nguyen TranChief Strategy Off…SELL$500K+10K$55.53Jan 21, 2023
Nguyen TranChief Strategy Off…EXERCISE$50K–$100K10K$6.73Jan 21, 2023
Cooke ShaneDirectorEXERCISE$15K–$50K5K$6.41Jan 13, 2023
Cooke ShaneDirectorSELL$100K–$500K5K$52.92Jan 13, 2023
Ekman LarsDirectorSELL$500K+16K$55.98Jan 6, 2023
Ekman LarsDirectorEXERCISE$100K–$500K16K$6.41Jan 6, 2023
COLLIER RICHARD TDirectorSELL$100K–$500K5K$52.67Jan 6, 2023
COLLIER RICHARD TDirectorEXERCISE$15K–$50K5K$6.41Jan 6, 2023
Nguyen TranChief Strategy Off…SELL$500K+10K$58.97Dec 24, 2022
Nguyen TranChief Strategy Off…EXERCISE$50K–$100K10K$6.73Dec 24, 2022
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Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Rubric Capital Management LP

SC 13G · Feb 13, 2026

6.8%

3.7M shares

ADAR1 Capital Management, LLC

SC 13G/A · Nov 15, 2025

2.7%

1.5M shares

Fennell Todd W.

SC 13G/A · Nov 12, 2025

8.4%

4.5M shares

SCULLY WILLIAM P

SC 13G/A · Nov 12, 2025

9.8%

5.3M shares

BlackRock, Inc.

SC 13G/A · Oct 17, 2025

5.7%

3.1M shares

ADAR1 Capital Management, LLC

SC 13G · Aug 15, 2025

6.3%

3.4M shares

Logos Global Management LP

SC 13G/A · Aug 14, 2025

0.0%

0 shares

T. Rowe Price Associates, Inc.

SC 13G/A · Aug 14, 2025

0.1%

71K shares

SCULLY WILLIAM P

SC 13G/A · Aug 13, 2025

9.9%

5.4M shares

Fennell Todd W.

SC 13G/A · Aug 13, 2025

8.1%

4.4M shares

Wellington Management Group LLP

SC 13G/A · Jun 5, 2025

0.2%

108K shares

Logos Global Management LP

SC 13G · Jun 4, 2025

5.5%

3.0M shares

EcoR1 Capital, LLC

SC 13D/A · May 30, 2025

0.0%

0 shares

Fennell Todd W.

SC 13G/A · May 15, 2025

8.5%

4.6M shares

SCULLY WILLIAM P

SC 13G/A · May 14, 2025

10.4%

5.6M shares

EcoR1 Capital, LLC

SC 13D/A · May 6, 2025

9.9%

5.3M shares

SCULLY WILLIAM P

SC 13G/A · Feb 21, 2025

10.3%

5.6M shares

Fennell Todd W.

SC 13G/A · Feb 14, 2025

8.6%

4.6M shares

Wellington Management Group LLP

SC 13G/A · Feb 10, 2025

9.5%

5.1M shares

EcoR1 Capital, LLC

SC 13D/A · Jan 4, 2025

21.5%

11.6M shares

7.1%

3.8M shares

Todd W. Fennell

SC 13G/A · Nov 13, 2024

5.9%

3.2M shares

William P. Scully 2

SC 13G/A · Nov 13, 2024

7.5%

403.6M shares

Wellington Management Group LLP

SC 13G · Nov 8, 2024

7.8%

4.2M shares

Wellington Management Group LLP

SC 13G/A · Nov 7, 2024

10.8%

5.8M shares

STATE STREET CORPORATION 04-2456637

SC 13G/A · Oct 18, 2024

3.1%

1.7M shares

Todd W. Fennell

SC 13G · Feb 14, 2024

5.8%

3.1M shares

William P. Scully 2

SC 13G · Feb 14, 2024

6.5%

350.2M shares

7.9%

4.2M shares

Avidity Partners Management LP

SC 13G/A · Feb 14, 2024

0.0%

0 shares

FMR LLC

SC 13G/A · Mar 10, 2023

10.0%

5.3M shares

Avidity Partners Management LP

SC 13G/A · Feb 14, 2023

5.7%

3.0M shares

William P. Scully

SC 13G/A · Feb 14, 2023

4.8%

2.5M shares

6.3%

3.2M shares

6.4%

3.0M shares

William P. Scully

SC 13G · Jun 27, 2022

5.4%

2.5M shares

3.9%

1.8M shares

12.7%

5.9M shares

EcoR1 Capital, LLC

SC 13D/A · Jan 13, 2022

24.9%

11.6M shares

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