PROTHENA CORP PUBLIC LTD CO
Total Trades
177
Buys
3
Sells
88
Largest Trade
$1M+
Insiders
14
Institutional Funds
137
Inst. Value
$1M+
Activist Filings
40
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Walker Karin L | Chief Accounting O… | EXERCISE | $50K–$100K | 5K | $15.04 | Jun 20, 2023 |
| Walker Karin L | Chief Accounting O… | SELL | $100K–$500K | 5K | $68.90 | Jun 20, 2023 |
| Garren Hideki | Chief Medical Offi… | SELL | $500K+ | 7K | $74.00 | Jun 16, 2023 |
| Garren Hideki | Chief Medical Offi… | EXERCISE | $100K–$500K | 7K | $24.90 | Jun 16, 2023 |
| Smith Brandon S. | COO | SELL | $100K–$500K | 5K | $73.98 | Jun 15, 2023 |
| Smith Brandon S. | COO | EXERCISE | $50K–$100K | 5K | $11.12 | Jun 15, 2023 |
| Garren Hideki | Chief Medical Offi… | EXERCISE | $100K–$500K | 5K | $24.90 | Jun 15, 2023 |
| Garren Hideki | Chief Medical Offi… | SELL | $100K–$500K | 5K | $74.22 | Jun 15, 2023 |
| Zago Wagner M. | Chief Scientific O… | SELL | $1M+ | 19K | $71.06 | Jun 8, 2023 |
| Zago Wagner M. | Chief Scientific O… | EXERCISE | $100K–$500K | 19K | $26.09 | Jun 8, 2023 |
| Karp Carol D. | Chief Regulatory O… | SELL | $1M+ | 20K | $71.05 | Jun 8, 2023 |
| Karp Carol D. | Chief Regulatory O… | EXERCISE | $100K–$500K | 20K | $13.19 | Jun 8, 2023 |
| Malecek Michael J | Chief Legal Officer | SELL | $100K–$500K | 5K | $64.64 | Jun 1, 2023 |
| Malecek Michael J | Chief Legal Officer | EXERCISE | $50K–$100K | 5K | $10.27 | Jun 1, 2023 |
| Walker Karin L | Chief Accounting O… | EXERCISE | $50K–$100K | 5K | $15.04 | May 20, 2023 |
| Walker Karin L | Chief Accounting O… | SELL | $100K–$500K | 5K | $74.00 | May 20, 2023 |
| Kinney Gene G. | President and CEO | SELL | $1M+ | 45K | $73.70 | May 18, 2023 |
| Kinney Gene G. | President and CEO | EXERCISE | $1M+ | 45K | $29.81 | May 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | SELL | $1M+ | 95K | $73.99 | May 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | EXERCISE | $1M+ | 95K | $26.15 | May 18, 2023 |
| Selkoe Dennis J. | Director | EXERCISE | $100K–$500K | 15K | $18.07 | May 6, 2023 |
| Selkoe Dennis J. | Director | SELL | $500K+ | 15K | $57.00 | May 6, 2023 |
| Malecek Michael J | Chief Legal Officer | EXERCISE | $50K–$100K | 5K | $10.27 | Apr 29, 2023 |
| Malecek Michael J | Chief Legal Officer | SELL | $100K–$500K | 5K | $53.46 | Apr 29, 2023 |
| Walker Karin L | Chief Accounting O… | SELL | $100K–$500K | 5K | $52.90 | Apr 22, 2023 |
| Walker Karin L | Chief Accounting O… | EXERCISE | $50K–$100K | 5K | $15.04 | Apr 22, 2023 |
| Malecek Michael J | Chief Legal Officer | EXERCISE | $50K–$100K | 5K | $10.27 | Apr 1, 2023 |
| Malecek Michael J | Chief Legal Officer | SELL | $100K–$500K | 5K | $49.02 | Apr 1, 2023 |
| Walker Karin L | Chief Accounting O… | EXERCISE | $50K–$100K | 5K | $15.04 | Mar 23, 2023 |
| Walker Karin L | Chief Accounting O… | SELL | $100K–$500K | 5K | $47.72 | Mar 23, 2023 |
| Walker Karin L | Chief Accounting O… | SELL | $500K+ | 20K | $48.42 | Mar 18, 2023 |
| Walker Karin L | Chief Accounting O… | EXERCISE | $100K–$500K | 20K | $15.04 | Mar 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | SELL | $100K–$500K | 10K | $48.43 | Mar 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | EXERCISE | $50K–$100K | 10K | $6.73 | Mar 18, 2023 |
| Malecek Michael J | Chief Legal Officer | EXERCISE | $100K–$500K | 15K | $10.27 | Mar 18, 2023 |
| Malecek Michael J | Chief Legal Officer | SELL | $500K+ | 15K | $48.44 | Mar 18, 2023 |
| Garren Hideki | Chief Medical Offi… | SELL | $500K+ | 12K | $48.41 | Mar 18, 2023 |
| Garren Hideki | Chief Medical Offi… | EXERCISE | $100K–$500K | 12K | $24.90 | Mar 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | SELL | $500K+ | 10K | $53.34 | Feb 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | EXERCISE | $50K–$100K | 10K | $6.73 | Feb 18, 2023 |
| Nguyen Tran | Chief Strategy Off… | SELL | $500K+ | 10K | $55.53 | Jan 21, 2023 |
| Nguyen Tran | Chief Strategy Off… | EXERCISE | $50K–$100K | 10K | $6.73 | Jan 21, 2023 |
| Cooke Shane | Director | EXERCISE | $15K–$50K | 5K | $6.41 | Jan 13, 2023 |
| Cooke Shane | Director | SELL | $100K–$500K | 5K | $52.92 | Jan 13, 2023 |
| Ekman Lars | Director | SELL | $500K+ | 16K | $55.98 | Jan 6, 2023 |
| Ekman Lars | Director | EXERCISE | $100K–$500K | 16K | $6.41 | Jan 6, 2023 |
| COLLIER RICHARD T | Director | SELL | $100K–$500K | 5K | $52.67 | Jan 6, 2023 |
| COLLIER RICHARD T | Director | EXERCISE | $15K–$50K | 5K | $6.41 | Jan 6, 2023 |
| Nguyen Tran | Chief Strategy Off… | SELL | $500K+ | 10K | $58.97 | Dec 24, 2022 |
| Nguyen Tran | Chief Strategy Off… | EXERCISE | $50K–$100K | 10K | $6.73 | Dec 24, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 137 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| Rubric Capital Management LP | 3.7M | $1M+ | SH |
| STATE STREET CORP | 2.3M | $1M+ | SH |
| ADAR1 Capital Management, LLC | 1.5M | $1M+ | SH |
| ADAR1 Capital Management, LLC | 1.5M | $1M+ | SH |
| ACADIAN ASSET MANAGEMENT LLC | 1.4M | $1M+ | SH |
| Palo Alto Investors LP | 1.3M | $1M+ | SH |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 978K | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 919K | $1M+ | SH |
| Point72 Asset Management, L.P. | 860K | $1M+ | SH |
| DIMENSIONAL FUND ADVISORS LP | 744K | $1M+ | SH |
| Mariner, LLC | 578K | $1M+ | SH |
| Birchview Capital, LP | 441K | $1M+ | SH |
| RENAISSANCE TECHNOLOGIES LLC | 436K | $1M+ | SH |
| BNP PARIBAS FINANCIAL MARKETS | 424K | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 357K | $1M+ | SH |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 298K | $1M+ | SH |
| Man Group plc | 270K | $1M+ | SH |
| JANE STREET GROUP, LLC | 245K | $1M+ | SH |
| VANGUARD GROUP INC | 241K | $1M+ | SH |
| Squarepoint Ops LLC | 218K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G · Feb 13, 2026
6.8%
3.7M shares
SC 13G/A · Nov 15, 2025
2.7%
1.5M shares
SC 13G/A · Nov 12, 2025
8.4%
4.5M shares
SC 13G/A · Nov 12, 2025
9.8%
5.3M shares
SC 13G/A · Oct 17, 2025
5.7%
3.1M shares
SC 13G · Aug 15, 2025
6.3%
3.4M shares
SC 13G/A · Aug 14, 2025
0.0%
0 shares
T. Rowe Price Associates, Inc.
SC 13G/A · Aug 14, 2025
0.1%
71K shares
SC 13G/A · Aug 13, 2025
9.9%
5.4M shares
SC 13G/A · Aug 13, 2025
8.1%
4.4M shares
Wellington Management Group LLP
SC 13G/A · Jun 5, 2025
0.2%
108K shares
SC 13G · Jun 4, 2025
5.5%
3.0M shares
SC 13D/A · May 30, 2025
0.0%
0 shares
SC 13G/A · May 15, 2025
8.5%
4.6M shares
SC 13G/A · May 14, 2025
10.4%
5.6M shares
SC 13D/A · May 6, 2025
9.9%
5.3M shares
SC 13G/A · Feb 21, 2025
10.3%
5.6M shares
SC 13G/A · Feb 14, 2025
8.6%
4.6M shares
Wellington Management Group LLP
SC 13G/A · Feb 10, 2025
9.5%
5.1M shares
SC 13D/A · Jan 4, 2025
21.5%
11.6M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Nov 14, 2024
7.1%
3.8M shares
SC 13G/A · Nov 13, 2024
5.9%
3.2M shares
SC 13G/A · Nov 13, 2024
7.5%
403.6M shares
Wellington Management Group LLP
SC 13G · Nov 8, 2024
7.8%
4.2M shares
Wellington Management Group LLP
SC 13G/A · Nov 7, 2024
10.8%
5.8M shares
STATE STREET CORPORATION 04-2456637
SC 13G/A · Oct 18, 2024
3.1%
1.7M shares
SC 13G · Feb 14, 2024
5.8%
3.1M shares
SC 13G · Feb 14, 2024
6.5%
350.2M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2024
7.9%
4.2M shares
Avidity Partners Management LP
SC 13G/A · Feb 14, 2024
0.0%
0 shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G · Jan 24, 2024
5.1%
0 shares
SC 13G/A · Mar 10, 2023
10.0%
5.3M shares
Avidity Partners Management LP
SC 13G/A · Feb 14, 2023
5.7%
3.0M shares
SC 13G/A · Feb 14, 2023
4.8%
2.5M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2023
6.3%
3.2M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Aug 10, 2022
6.4%
3.0M shares
SC 13G · Jun 27, 2022
5.4%
2.5M shares
First Light Asset Management, LLC 46-3521994
SC 13G · Mar 1, 2022
3.9%
1.8M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2022
12.7%
5.9M shares
SC 13D/A · Jan 13, 2022
24.9%
11.6M shares