Denali Therapeutics Inc.
Total Trades
112
Buys
0
Sells
94
Largest Trade
N/A
Insiders
8
Institutional Funds
196
Inst. Value
$1M+
Activist Filings
27
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Watts Ryan J. | President and CEO | SELL | $500K+ | 35K | $16.50 | Jan 8, 2026 |
| Schuth Alexander O. | COFO and Secretary | SELL | $100K–$500K | 17K | $16.50 | Jan 8, 2026 |
| Watts Ryan J. | President and CEO | EXERCISE | $500K+ | 495K | $1.05 | Jul 11, 2025 |
| Watts Ryan J. | President and CEO | SELL | $1M+ | 495K | $15.00 | Jul 11, 2025 |
| Ho Carole | Chief Medical Offi… | SELL | $100K–$500K | 15K | $20.33 | Jan 9, 2025 |
| Schuth Alexander O. | COFO and Secretary | SELL | $100K–$500K | 15K | $20.33 | Jan 9, 2025 |
| Watts Ryan J. | President and CEO | SELL | $500K+ | 37K | $20.34 | Jan 9, 2025 |
| Krognes Steve E. | Director | SELL | $50K–$100K | 3K | $20.81 | Jan 9, 2025 |
| Krognes Steve E. | Director | SELL | $500K+ | 30K | $20.25 | Jan 3, 2025 |
| SATO VICKI L | Director | SELL | $50K–$100K | 3K | $20.91 | Jan 3, 2025 |
| Schenkein David P | Director | EXERCISE | $500K+ | 47K | $18.00 | Nov 13, 2024 |
| Schenkein David P | Director | SELL | $1M+ | 59K | $32.51 | Nov 13, 2024 |
| Schuth Alexander O. | COFO and Secretary | EXERCISE | $50K–$100K | 16K | $5.28 | Nov 12, 2024 |
| Schuth Alexander O. | COFO and Secretary | SELL | $100K–$500K | 16K | $29.91 | Nov 12, 2024 |
| SATO VICKI L | Director | SELL | $15K–$50K | 1K | $30.00 | Nov 12, 2024 |
| SATO VICKI L | Director | SELL | $50K–$100K | 3K | $27.07 | Nov 5, 2024 |
| Watts Ryan J. | President and CEO | EXERCISE | $15K–$50K | 40K | $0.68 | Oct 22, 2024 |
| Watts Ryan J. | President and CEO | SELL | $1M+ | 40K | $27.69 | Oct 22, 2024 |
| Krognes Steve E. | Director | SELL | $500K+ | 30K | $29.03 | Oct 2, 2024 |
| Watts Ryan J. | President and CEO | SELL | $50K–$100K | 2K | $23.79 | Aug 22, 2024 |
| Krognes Steve E. | Director | SELL | $15K–$50K | 2K | $23.79 | Aug 22, 2024 |
| Schuth Alexander O. | COFO and Secretary | SELL | $100K–$500K | 8K | $23.99 | Aug 22, 2024 |
| Ho Carole | Chief Medical Offi… | SELL | $500K+ | 22K | $24.49 | Aug 22, 2024 |
| Krognes Steve E. | Director | SELL | $500K+ | 31K | $22.11 | Jul 4, 2024 |
| SATO VICKI L | Director | SELL | $50K–$100K | 3K | $22.14 | Jul 4, 2024 |
| Cook Jennifer E. | Director | SELL | $15K–$50K | 1K | $21.73 | Jun 11, 2024 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $18.29 | Apr 17, 2024 |
| Krognes Steve E. | Director | SELL | $1M+ | 93K | $20.50 | Apr 2, 2024 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $18.37 | Feb 20, 2024 |
| Krognes Steve E. | Director | SELL | $15K–$50K | 3K | $17.29 | Feb 16, 2024 |
| Watts Ryan J. | President and CEO | SELL | $100K–$500K | 10K | $17.29 | Feb 16, 2024 |
| Ho Carole | Chief Medical Offi… | SELL | $50K–$100K | 4K | $17.46 | Feb 16, 2024 |
| Schuth Alexander O. | COFO and Secretary | SELL | $100K–$500K | 23K | $17.62 | Feb 16, 2024 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $18.42 | Jan 18, 2024 |
| Ho Carole | Chief Medical Offi… | SELL | $50K–$100K | 5K | $19.02 | Jan 13, 2024 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $19.13 | Nov 16, 2023 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $20.66 | Oct 18, 2023 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $23.62 | Sep 19, 2023 |
| Schuth Alexander O. | COFO and Secretary | SELL | $50K–$100K | 3K | $23.17 | Aug 25, 2023 |
| Ho Carole | Chief Medical Offi… | SELL | $50K–$100K | 3K | $23.22 | Aug 25, 2023 |
| Ho Carole | Chief Medical Offi… | SELL | $50K–$100K | 2K | $22.60 | Aug 23, 2023 |
| Schuth Alexander O. | COFO and Secretary | SELL | $50K–$100K | 2K | $22.59 | Aug 23, 2023 |
| Watts Ryan J. | President and CEO | SELL | $50K–$100K | 2K | $22.59 | Aug 23, 2023 |
| Krognes Steve E. | Director | SELL | $15K–$50K | 1K | $22.60 | Aug 23, 2023 |
| SATO VICKI L | Director | SELL | $15K–$50K | 2K | $24.30 | Aug 17, 2023 |
| Ho Carole | Chief Medical Offi… | SELL | $50K–$100K | 3K | $23.79 | Aug 16, 2023 |
| Schuth Alexander O. | COFO and Secretary | SELL | $50K–$100K | 3K | $23.67 | Aug 16, 2023 |
| Watts Ryan J. | President and CEO | EXERCISE | $1K–$15K | 3K | $0.68 | Aug 14, 2023 |
| Watts Ryan J. | President and CEO | SELL | $50K–$100K | 3K | $25.03 | Aug 14, 2023 |
| Ho Carole | Chief Medical Offi… | SELL | $50K–$100K | 3K | $24.15 | Aug 14, 2023 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 196 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| STATE STREET CORP | 6.3M | $1M+ | SH |
| NORGES BANK | 5.1M | $1M+ | SH |
| Capital Research Global Investors | 3.7M | $1M+ | SH |
| ALLIANCEBERNSTEIN L.P. | 3.6M | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 3.0M | $1M+ | SH |
| Fisher Asset Management, LLC | 2.6M | $1M+ | SH |
| DIMENSIONAL FUND ADVISORS LP | 2.2M | $1M+ | SH |
| Aberdeen Group plc | 2.0M | $1M+ | SH |
| Point72 Asset Management, L.P. | 1.7M | $1M+ | SH |
| BAILLIE GIFFORD & CO | 1.5M | $1M+ | SH |
| PRINCIPAL FINANCIAL GROUP INC | 1.5M | $1M+ | SH |
| Siren, L.L.C. | 1.4M | $1M+ | SH |
| Pictet Asset Management Holding SA | 1.3M | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.2M | $1M+ | SH |
| Candriam S.C.A. | 1.2M | $1M+ | SH |
| MASTERS CAPITAL MANAGEMENT LLC | 1.0M | $1M+ | SH |
| Alyeska Investment Group, L.P. | 859K | $1M+ | SH |
| Defilade Capital Management, L.P. | 657K | $1M+ | SH |
| Palo Alto Investors LP | 641K | $1M+ | SH |
| Cercano Management LLC | 625K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G/A · Nov 5, 2025
5.8%
8.5M shares
Wellington Management Group LLP
SC 13G/A · Aug 12, 2025
3.9%
5.7M shares
SC 13G · Aug 8, 2025
5.6%
2.2M shares
SC 13G/A · Apr 17, 2025
7.2%
10.5M shares
Capital Research Global Investors
SC 13G/A · Feb 13, 2025
3.8%
5.5M shares
SC 13G/A · Feb 12, 2025
7.2%
2.7M shares
SC 13G/A · Feb 12, 2025
8.6%
12.3M shares
Capital Research Global Investors 95-1411037
SC 13G · Nov 12, 2024
5.5%
7.9M shares
SC 13G/A · Nov 12, 2024
7.1%
10.1M shares
SC 13G/A · Nov 8, 2024
9.6%
13.8M shares
Wellington Management Group LLP
SC 13G/A · Nov 8, 2024
7.5%
10.7M shares
SC 13G/A · Nov 7, 2024
1.0%
7.2M shares
SC 13G/A · Oct 21, 2024
9.6%
13.8M shares
SC 13G · Aug 16, 2024
5.0%
7.2M shares
The Vanguard Group - 23-1945930
SC 13G/A · Feb 13, 2024
7.8%
10.8M shares
SC 13G/A · Feb 13, 2024
0.0%
0 shares
SC 13G/A · Feb 13, 2024
1.0%
12.8M shares
Baillie Gifford & Co (Scottish partnership)
SC 13G/A · Jan 30, 2024
10.3%
14.3M shares
Temasek Holdings (Private) Limited
SC 13G/A · Jan 30, 2024
4.9%
6.9M shares
SC 13G/A · Jan 25, 2024
8.4%
11.5M shares
Temasek Holdings (Private) Limited
SC 13G · Mar 30, 2023
5.0%
6.9M shares
SC 13G/A · Jan 31, 2023
6.9%
9.3M shares
Baillie Gifford & Co (Scottish partnership)
SC 13G/A · Jan 20, 2023
11.1%
15.1M shares
SC 13G/A · Feb 14, 2022
6.4%
7.8M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2022
3.7%
4.6M shares
Baillie Gifford & Co (Scottish partnership)
SC 13G/A · Jan 18, 2022
12.3%
15.1M shares