AMLX

Amylyx Pharmaceuticals, Inc.

Pharmaceutical PreparationsNasdaqAccelerated filer<br>Smaller reporting company

Total Trades

Buys

Sells

Largest Trade

N/A

Insiders

Institutional Funds

128

Inst. Value

$1M+

Activist Filings

Insider Trades

Insider	Title	Type	Value	Shares	Price	Date
Klee Justin B.	CEO	GRANT	N/A	50K	—	Mar 21, 2023
MILNE GEORGE M JR	Director	SELL	$1M+	35K	$31.89	Mar 21, 2023
Yeramian Patrick D	Chief Medical Offi…	GRANT	N/A	9K	—	Mar 21, 2023
Yeramian Patrick D	Chief Medical Offi…	SELL	$1M+	55K	$31.87	Mar 21, 2023
Firestone Karen	Director	BUY	$15K–$50K	1K	$31.99	Mar 21, 2023
Cohen Joshua B	CEO	GRANT	N/A	50K	—	Mar 21, 2023
Cohen Joshua B	CEO	SELL	$1M+	100K	$31.86	Mar 21, 2023
FRATES JAMES M	CFO	GRANT	N/A	22K	—	Mar 21, 2023
FRATES JAMES M	CFO	SELL	$1M+	33K	$31.89	Mar 21, 2023
Morningside Venture Investments Ltd	10% Owner	SELL	$100K–$500K	9K	$32.55	Mar 17, 2023
Morningside Venture Investments Ltd	10% Owner	SELL	$1M+	221K	$33.68	Mar 16, 2023
Morningside Venture Investments Ltd	10% Owner	SELL	$1M+	50K	$33.75	Mar 6, 2023
Mazzariello Gina	Chief Legal Officer	SELL	$100K–$500K	4K	$34.49	Feb 28, 2023
Morningside Venture Investments Ltd	10% Owner	SELL	$1M+	50K	$34.73	Feb 28, 2023
Morningside Venture Investments Ltd	10% Owner	SELL	$1M+	100K	$35.78	Feb 24, 2023
Yeramian Patrick D	Chief Medical Offi…	SELL	$50K–$100K	2K	$36.30	Jan 11, 2023
Cohen Joshua B	CEO	SELL	$100K–$500K	6K	$36.30	Jan 11, 2023
FRATES JAMES M	CFO	SELL	$50K–$100K	3K	$36.30	Jan 11, 2023
Olinger Margaret	Chief Commercial O…	SELL	$50K–$100K	2K	$36.30	Jan 11, 2023
Klee Justin B.	CEO	SELL	$100K–$500K	6K	$36.30	Jan 11, 2023
VIKING GLOBAL INVESTORS LP	10% Owner	SELL	$1M+	1.4M	$29.80	Sep 10, 2022
ALS Invest 1 B.V.	10% Owner	SELL	$1M+	61K	$20.70	Jul 8, 2022
Morningside Venture Investments Ltd	10% Owner	BUY	$1M+	263K	$19.00	Jan 25, 2022
VIKING GLOBAL INVESTORS LP	10% Owner	BUY	$1M+	2.3M	$19.00	Jan 14, 2022
FONTEYNE PAUL R.	Director	BUY	$50K–$100K	4K	$19.00	Jan 11, 2022
Cheng Isaac	Director	BUY	$100K–$500K	7K	$19.00	Jan 11, 2022
MILNE GEORGE M JR	Director	BUY	$100K–$500K	26K	$19.00	Jan 11, 2022
Olinger Margaret	Chief Commercial O…	BUY	$100K–$500K	7K	$19.00	Jan 11, 2022
Olinger Margaret	Chief Commercial O…	GRANT	N/A	28K	—	Jan 11, 2022

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Institutional Ownership

13F filings as of Dec 31, 2025 · 128 funds holding

Fund	Shares	Value	Type
PERCEPTIVE ADVISORS LLC	8.3M	$1M+	SH
VANGUARD GROUP INC	5.1M	$1M+	SH
First Light Asset Management, LLC	3.4M	$1M+	SH
Almitas Capital LLC	2.1M	$1M+	SH
STATE STREET CORP	2.1M	$1M+	SH
GEODE CAPITAL MANAGEMENT, LLC	1.9M	$1M+	SH
EVENTIDE ASSET MANAGEMENT, LLC	1.5M	$1M+	SH
Connor, Clark & Lunn Investment Management Ltd.	1.0M	$1M+	SH
Logos Global Management LP	950K	$1M+	SH
GOLDMAN SACHS GROUP INC	895K	$1M+	SH
ADAR1 Capital Management, LLC	890K	$1M+	SH
ADAR1 Capital Management, LLC	890K	$1M+	SH
BALYASNY ASSET MANAGEMENT L.P.	859K	$1M+	SH
Nantahala Capital Management, LLC	836K	$1M+	SH
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	713K	$1M+	SH
DIMENSIONAL FUND ADVISORS LP	686K	$1M+	SH
Sofinnova Investments, Inc.	527K	$1M+	SH
SILVERARC CAPITAL MANAGEMENT, LLC	506K	$1M+	SH
Cormorant Asset Management, LP	400K	$1M+	SH
Patient Square Capital LP	350K	$1M+	SH