INSMED Inc
Total Trades
214
Buys
5
Sells
140
Largest Trade
N/A
Insiders
12
Institutional Funds
551
Inst. Value
$1M+
Activist Filings
27
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Lewis William | Chair and CEO | SELL | $1M+ | 26K | $77.03 | Mar 19, 2025 |
| Lewis William | Chair and CEO | EXERCISE | $500K+ | 26K | $19.58 | Mar 19, 2025 |
| Lewis William | Chair and CEO | EXERCISE | $500K+ | 26K | $19.58 | Feb 20, 2025 |
| Lewis William | Chair and CEO | SELL | $1M+ | 26K | $81.03 | Feb 20, 2025 |
| Bonstein Sara | CFO | SELL | $1M+ | 18K | $80.31 | Feb 20, 2025 |
| Schaeffer Orlov S Nicole | Chief People Strat… | EXERCISE | $1M+ | 91K | $15.04 | Jan 31, 2025 |
| Schaeffer Orlov S Nicole | Chief People Strat… | SELL | $1M+ | 91K | $80.00 | Jan 31, 2025 |
| Flammer Martina M.D. | Chief Medical Offi… | SELL | $50K–$100K | 1K | $68.72 | Jan 16, 2025 |
| Adsett Roger | COO | SELL | $100K–$500K | 1K | $68.72 | Jan 16, 2025 |
| Schaeffer Orlov S Nicole | Chief People Strat… | SELL | $50K–$100K | 872 | $68.72 | Jan 16, 2025 |
| Lewis William | Chair and CEO | SELL | $1M+ | 39K | $70.18 | Jan 16, 2025 |
| Lewis William | Chair and CEO | EXERCISE | $500K+ | 26K | $19.58 | Jan 16, 2025 |
| Flammer Martina M.D. | Chief Medical Offi… | SELL | $500K+ | 11K | $64.70 | Jan 10, 2025 |
| Flammer Martina M.D. | Chief Medical Offi… | GRANT | N/A | 7K | — | Jan 10, 2025 |
| Bonstein Sara | CFO | GRANT | N/A | 7K | — | Jan 10, 2025 |
| Bonstein Sara | CFO | SELL | $100K–$500K | 6K | $65.43 | Jan 10, 2025 |
| Schaeffer Orlov S Nicole | Chief People Strat… | GRANT | N/A | 6K | — | Jan 10, 2025 |
| Schaeffer Orlov S Nicole | Chief People Strat… | SELL | $500K+ | 8K | $64.74 | Jan 10, 2025 |
| Wise John Drayton | Chief Commercial O… | SELL | $500K+ | 14K | $65.95 | Jan 10, 2025 |
| Wise John Drayton | Chief Commercial O… | EXERCISE | $100K–$500K | 10K | $16.07 | Jan 10, 2025 |
| Wise John Drayton | Chief Commercial O… | GRANT | N/A | 7K | — | Jan 10, 2025 |
| Lewis William | Chair and CEO | GRANT | N/A | 23K | — | Jan 10, 2025 |
| Lewis William | Chair and CEO | SELL | $500K+ | 15K | $65.48 | Jan 10, 2025 |
| Smith Michael Alexander | Chief Legal Officer | GRANT | N/A | 6K | — | Jan 10, 2025 |
| Smith Michael Alexander | Chief Legal Officer | SELL | $100K–$500K | 4K | $65.82 | Jan 10, 2025 |
| Adsett Roger | COO | SELL | $500K+ | 9K | $64.78 | Jan 10, 2025 |
| Adsett Roger | COO | GRANT | N/A | 7K | — | Jan 10, 2025 |
| Lewis William | Chair and CEO | EXERCISE | $500K+ | 26K | $19.58 | Jan 3, 2025 |
| Lewis William | Chair and CEO | SELL | $1M+ | 26K | $69.85 | Jan 3, 2025 |
| Lewis William | Chair and CEO | SELL | $1M+ | 26K | $69.91 | Dec 20, 2024 |
| Lewis William | Chair and CEO | EXERCISE | $500K+ | 26K | $19.58 | Dec 20, 2024 |
| Flammer Martina M.D. | Chief Medical Offi… | EXERCISE | $500K+ | 21K | $23.75 | Jun 12, 2024 |
| Flammer Martina M.D. | Chief Medical Offi… | SELL | $1M+ | 21K | $60.00 | Jun 12, 2024 |
| Schaeffer Orlov S Nicole | Chief People Strat… | SELL | $1M+ | 55K | $55.33 | Jun 5, 2024 |
| Schaeffer Orlov S Nicole | Chief People Strat… | EXERCISE | $1M+ | 55K | $21.09 | Jun 5, 2024 |
| Wise John Drayton | Chief Commercial O… | SELL | $100K–$500K | 8K | $49.79 | May 30, 2024 |
| Wise John Drayton | Chief Commercial O… | EXERCISE | $50K–$100K | 6K | $12.58 | May 30, 2024 |
| Smith Michael Alexander | Chief Legal Officer | EXERCISE | $500K+ | 39K | $14.27 | May 30, 2024 |
| Smith Michael Alexander | Chief Legal Officer | SELL | $1M+ | 45K | $49.53 | May 30, 2024 |
| Schaeffer Orlov S Nicole | Chief People Strat… | SELL | $1M+ | 28K | $49.53 | May 30, 2024 |
| Schaeffer Orlov S Nicole | Chief People Strat… | EXERCISE | $100K–$500K | 28K | $12.58 | May 30, 2024 |
| Flammer Martina M.D. | Chief Medical Offi… | SELL | $1M+ | 125K | $50.53 | May 30, 2024 |
| Flammer Martina M.D. | Chief Medical Offi… | EXERCISE | $1M+ | 125K | $23.68 | May 30, 2024 |
| Bonstein Sara | CFO | SELL | $1M+ | 241K | $50.00 | May 30, 2024 |
| Bonstein Sara | CFO | EXERCISE | $1M+ | 241K | $26.55 | May 30, 2024 |
| Schaeffer Orlov S Nicole | Chief People Strat… | SELL | $500K+ | 22K | $32.00 | Jan 2, 2024 |
| Schaeffer Orlov S Nicole | Chief People Strat… | EXERCISE | $100K–$500K | 22K | $20.49 | Jan 2, 2024 |
| Flammer Martina M.D. | Chief Medical Offi… | SELL | $500K+ | 28K | $30.00 | Dec 22, 2023 |
| Flammer Martina M.D. | Chief Medical Offi… | EXERCISE | $500K+ | 28K | $23.66 | Dec 22, 2023 |
| Bonstein Sara | CFO | SELL | $100K–$500K | 13K | $30.00 | Dec 22, 2023 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 551 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| Darwin Global Management, Ltd. | 20.9M | $1M+ | SH |
| STATE STREET CORP | 5.2M | $1M+ | SH |
| Capital International Investors | 5.2M | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 3.8M | $1M+ | SH |
| NORGES BANK | 2.9M | $1M+ | SH |
| Duquesne Family Office LLC | 1.5M | $1M+ | SH |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1.2M | $1M+ | SH |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 1.2M | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.0M | $1M+ | SH |
| Pictet Asset Management Holding SA | 959K | $1M+ | SH |
| Jefferies Financial Group Inc. | 926K | $1M+ | SH |
| BNP PARIBAS FINANCIAL MARKETS | 915K | $1M+ | SH |
| Clearbridge Investments, LLC | 819K | $1M+ | SH |
| PRINCIPAL FINANCIAL GROUP INC | 767K | $1M+ | SH |
| LORD, ABBETT & CO. LLC | 715K | $1M+ | SH |
| Artia Global Partners LP | 682K | $1M+ | SH |
| VICTORY CAPITAL MANAGEMENT INC | 647K | $1M+ | SH |
| ALLIANCEBERNSTEIN L.P. | 643K | $1M+ | SH |
| Fiera Capital Corp | 589K | $1M+ | SH |
| Swiss National Bank | 579K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G/A · Jan 21, 2026
6.6%
14.1M shares
Darwin Global Management, Ltd.
SC 13G/A · Nov 14, 2025
9.7%
20.5M shares
T. Rowe Price Associates, Inc.
SC 13G/A · Nov 14, 2025
3.3%
6.9M shares
T. Rowe Price Associates, Inc.
SC 13G/A · Aug 14, 2025
5.9%
11.2M shares
SC 13G · Jul 30, 2025
7.9%
15.2M shares
SC 13G/A · Jul 18, 2025
5.1%
9.7M shares
Darwin Global Management, Ltd.
SC 13G/A · May 15, 2025
8.5%
15.4M shares
Darwin Global Management, Ltd.
SC 13G/A · Feb 14, 2025
7.2%
13.0M shares
SC 13G/A · Jan 8, 2025
10.2%
18.2M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Nov 14, 2024
7.3%
12.6M shares
Darwin Global Management, Ltd.
SC 13G · Sep 3, 2024
5.7%
9.7M shares
T. Rowe Price Investment Management, Inc. 85-4328500
SC 13G/A · Feb 16, 2024
4.1%
5.9M shares
T. Rowe Price Investment Management, Inc. 85-4328500
SC 13G · Feb 14, 2024
4.1%
5.9M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2024
7.5%
10.8M shares
The Vanguard Group - 23-1945930
SC 13G/A · Feb 13, 2024
9.9%
14.1M shares
SC 13G/A · Jan 25, 2024
8.0%
11.5M shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G/A · Jan 22, 2024
4.2%
0 shares
The Vanguard Group - 23-1945930
SC 13G/A · Nov 13, 2023
10.1%
14.4M shares
SC 13G/A · Feb 14, 2023
4.3%
5.9M shares
T. Rowe Price Investment Management, Inc. 85-4328500
SC 13G · Feb 14, 2023
6.2%
8.4M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2023
7.4%
10.0M shares
SC 13G/A · Feb 3, 2023
8.2%
11.1M shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G · Feb 3, 2023
5.1%
0 shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Aug 10, 2022
7.7%
9.2M shares
SC 13G/A · Feb 14, 2022
5.1%
6.0M shares
T. ROWE PRICE ASSOCIATES, INC. 52-0556948
SC 13G/A · Feb 14, 2022
12.9%
15.3M shares
Janus Henderson Group plc EIN #00-0000000
SC 13G/A · Feb 10, 2022
6.7%
7.9M shares