BIOCRYST PHARMACEUTICALS INC
Total Trades
42
Buys
2
Sells
27
Largest Trade
N/A
Insiders
15
Institutional Funds
214
Inst. Value
$1M+
Activist Filings
20
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Barnes Alane P | Chief Legal Officer | SELL | $100K–$500K | 22K | $7.65 | Dec 23, 2025 |
| Barnes Alane P | Chief Legal Officer | SELL | $100K–$500K | 21K | $7.65 | Dec 16, 2025 |
| Barnes Alane P | Chief Legal Officer | SELL | $1M+ | 162K | $7.21 | Dec 3, 2025 |
| Barnes Alane P | Chief Legal Officer | EXERCISE | $100K–$500K | 91K | $3.22 | Dec 3, 2025 |
| SANDERS MACHELLE | Director | SELL | $50K–$100K | 10K | $7.14 | Nov 17, 2025 |
| McKee Amy E | Director | SELL | $50K–$100K | 9K | $6.32 | Jun 25, 2024 |
| SANDERS MACHELLE | Director | SELL | $15K–$50K | 5K | $6.00 | Jun 17, 2024 |
| HEGGIE THERESA | Director | SELL | $15K–$50K | 7K | $6.11 | Jun 14, 2024 |
| HEGGIE THERESA | Director | GRANT | N/A | 7K | — | Jun 14, 2024 |
| LEVIN ALAN G | Director | BUY | $15K–$50K | 8K | $6.36 | May 31, 2024 |
| ASELAGE STEVE | Director | BUY | $15K–$50K | 3K | $6.40 | May 29, 2024 |
| SANDERS MACHELLE | Director | GRANT | N/A | 17K | — | Jun 15, 2023 |
| SANDERS MACHELLE | Director | SELL | $15K–$50K | 4K | $7.98 | Jun 15, 2023 |
| Hutson Nancy J | Director | GRANT | N/A | 17K | — | Jun 15, 2023 |
| Hutson Nancy J | Director | SELL | $100K–$500K | 13K | $8.04 | Jun 15, 2023 |
| Thackray Helen M. | Chief R&D Officer | SELL | $50K–$100K | 7K | $8.29 | Apr 5, 2023 |
| Stonehouse Jon P | President & CEO | EXERCISE | $500K+ | 100K | $5.45 | Feb 2, 2023 |
| Stonehouse Jon P | President & CEO | SELL | $1M+ | 100K | $10.38 | Feb 2, 2023 |
| Stonehouse Jon P | President & CEO | SELL | $100K–$500K | 14K | $10.90 | Dec 19, 2022 |
| Thackray Helen M. | Chief R&D Officer | SELL | $15K–$50K | 3K | $10.89 | Dec 19, 2022 |
| Doyle Anthony | CFO | SELL | $50K–$100K | 6K | $10.90 | Dec 19, 2022 |
| Gayer Charles K | Chief Commercial O… | SELL | $50K–$100K | 6K | $10.90 | Dec 19, 2022 |
| Jones Michael L | Exec. Director | SELL | $1K–$15K | 445 | $10.90 | Dec 19, 2022 |
| Barnes Alane P | Chief Legal Officer | SELL | $15K–$50K | 4K | $10.88 | Dec 19, 2022 |
| Jones Michael L | Exec. Director | EXERCISE | $1K–$15K | 9K | $1.42 | Dec 2, 2022 |
| Jones Michael L | Exec. Director | SELL | $100K–$500K | 9K | $13.01 | Dec 2, 2022 |
| Stonehouse Jon P | President & CEO | SELL | $1M+ | 298K | $12.94 | Dec 2, 2022 |
| Stonehouse Jon P | President & CEO | EXERCISE | $100K–$500K | 298K | $1.42 | Dec 2, 2022 |
| Babu Yarlagadda S | Chief Discovery Of… | EXERCISE | $100K–$500K | 100K | $1.42 | Nov 16, 2022 |
| Babu Yarlagadda S | Chief Discovery Of… | SELL | $100K–$500K | 32K | $13.88 | Nov 16, 2022 |
| ABERCROMBIE GEORGE B | Director | SELL | $50K–$100K | 5K | $11.04 | Apr 20, 2022 |
| ABERCROMBIE GEORGE B | Director | EXERCISE | $15K–$50K | 5K | $3.32 | Apr 20, 2022 |
| Thackray Helen M. | Chief R&D Officer | SELL | $100K–$500K | 8K | $16.20 | Apr 4, 2022 |
| Sheridan William P | Chief Medical Offi… | SELL | $1M+ | 161K | $16.88 | Mar 14, 2022 |
| Sheridan William P | Chief Medical Offi… | EXERCISE | $100K–$500K | 148K | $3.22 | Mar 14, 2022 |
| Babu Yarlagadda S | Chief Discovery Of… | SELL | $100K–$500K | 20K | $17.16 | Mar 9, 2022 |
| Jones Michael L | Exec. Director | SELL | $15K–$50K | 2K | $17.20 | Mar 3, 2022 |
| Jones Michael L | Exec. Director | EXERCISE | $1K–$15K | 2K | $4.73 | Mar 3, 2022 |
| ABERCROMBIE GEORGE B | Director | EXERCISE | $15K–$50K | 5K | $3.32 | Feb 16, 2022 |
| ABERCROMBIE GEORGE B | Director | SELL | $50K–$100K | 5K | $18.50 | Feb 16, 2022 |
| Stonehouse Jon P | President & CEO | SELL | $1M+ | 184K | $15.04 | Jan 13, 2022 |
| Stonehouse Jon P | President & CEO | EXERCISE | $500K+ | 184K | $4.73 | Jan 13, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 214 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 15.8M | $1M+ | SH |
| STATE STREET CORP | 11.1M | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 4.4M | $1M+ | SH |
| PERCEPTIVE ADVISORS LLC | 3.2M | $1M+ | SH |
| BNP PARIBAS FINANCIAL MARKETS | 2.5M | $1M+ | SH |
| Fisher Asset Management, LLC | 2.5M | $1M+ | SH |
| RENAISSANCE TECHNOLOGIES LLC | 2.1M | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 2.0M | $1M+ | SH |
| ORBIMED ADVISORS LLC | 1.7M | $1M+ | SH |
| Squarepoint Ops LLC | 1.7M | $1M+ | SH |
| Nantahala Capital Management, LLC | 1.4M | $1M+ | SH |
| Point72 Asset Management, L.P. | 1.2M | $1M+ | SH |
| DIMENSIONAL FUND ADVISORS LP | 1.2M | $1M+ | SH |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1.0M | $1M+ | SH |
| Hudson Bay Capital Management LP | 1.0M | $1M+ | SH |
| Aberdeen Group plc | 914K | $1M+ | SH |
| SPHERA FUNDS MANAGEMENT LTD. | 838K | $1M+ | SH |
| TANG CAPITAL MANAGEMENT LLC | 800K | $1M+ | SH |
| Pictet Asset Management Holding SA | 741K | $1M+ | SH |
| BARCLAYS PLC | 726K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G/A · Feb 12, 2026
6.8%
14.3M shares
SC 13G · Feb 9, 2026
5.3%
11.1M shares
SC 13G · Nov 13, 2025
7.3%
15.3M shares
SC 13G · Sep 19, 2025
5.8%
12.2M shares
SC 13G/A · May 15, 2025
4.2%
8.7M shares
SC 13G/A · Apr 17, 2025
8.4%
17.5M shares
SC 13G/A · Nov 7, 2024
10.0%
20.7M shares
SC 13G/A · Nov 7, 2024
9.8%
20.3M shares
SC 13G/A · Nov 4, 2024
9.8%
20.3M shares
STATE STREET CORPORATION 04-2456637
SC 13G/A · Oct 17, 2024
4.3%
8.8M shares
SC 13G/A · Sep 10, 2024
10.2%
21.0M shares
SC 13G/A · Feb 14, 2024
4.9%
10.1M shares
SC 13G · Feb 14, 2024
6.4%
13.1M shares
The Vanguard Group - 23-1945930
SC 13G/A · Feb 13, 2024
8.7%
17.8M shares
SC 13G/A · Jan 24, 2024
9.1%
18.7M shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G/A · Jan 24, 2024
6.2%
0 shares
SC 13G/A · Feb 14, 2023
9.9%
19.1M shares
SC 13G/A · Feb 3, 2023
8.0%
14.9M shares
SC 13G/A · Feb 14, 2022
9.9%
18.4M shares
SC 13G/A · Feb 1, 2022
8.2%
14.8M shares