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ANNX

Annexon, Inc.

Pharmaceutical PreparationsNasdaqNon-accelerated filer<br>Smaller reporting company

Total Trades

59

Buys

21

Sells

33

Largest Trade

N/A

Insiders

10

Institutional Funds

114

Inst. Value

$1M+

Activist Filings

50

Insider Trades

Insider	Title	Type	Value	Shares	Price	Date
Yednock Ted	EVP & Chief Innova…	SELL	$50K–$100K	21K	$4.52	Dec 29, 2023
Satter Muneer A	Director	BUY	$1M+	350K	$2.88	Dec 28, 2023
Bain Capital Life Sciences Investors, LLC	10% Owner	BUY	$500K+	300K	$2.13	May 31, 2023
Love Douglas	President & CEO	SELL	$15K–$50K	7K	$5.87	Feb 17, 2023
Overdorf Michael	EVP & Chief Busine…	SELL	$1K–$15K	2K	$6.30	Feb 16, 2023
Lew Jennifer	CFO	SELL	$1K–$15K	2K	$6.31	Feb 15, 2023
Satter Muneer A	Director	BUY	$1M+	2.6M	$6.80	Feb 14, 2023
Satter Muneer A	Director	BUY	$1M+	2.5M	$3.84	Jul 12, 2022
Love Douglas	President & CEO	BUY	$100K–$500K	60K	$2.45	Apr 18, 2022

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Institutional Ownership

13F filings as of Dec 31, 2025 · 114 funds holding

Fund	Shares	Value	Type
Redmile Group, LLC	10.1M	$1M+	SH
VANGUARD GROUP INC	6.9M	$1M+	SH
Bain Capital Life Sciences Investors, LLC	5.2M	$1M+	SH
STATE STREET CORP	4.7M	$1M+	SH
BALYASNY ASSET MANAGEMENT L.P.	3.3M	$1M+	SH
Longaeva Partners L.P.	3.1M	$1M+	SH
MAK CAPITAL ONE LLC	3.0M	$1M+	SH
GEODE CAPITAL MANAGEMENT, LLC	2.5M	$1M+	SH
Palo Alto Investors LP	2.4M	$1M+	SH
SPHERA FUNDS MANAGEMENT LTD.	1.3M	$1M+	SH
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1.1M	$1M+	SH
J. Goldman & Co LP	994K	$1M+	SH
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	903K	$1M+	SH
ACADIAN ASSET MANAGEMENT LLC	861K	$1M+	SH
RENAISSANCE TECHNOLOGIES LLC	803K	$1M+	SH
AQR CAPITAL MANAGEMENT LLC	761K	$1M+	SH
SIRIOS CAPITAL MANAGEMENT L P	710K	$1M+	SH
JACOBS LEVY EQUITY MANAGEMENT, INC	684K	$1M+	SH
DIMENSIONAL FUND ADVISORS LP	651K	$1M+	SH
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	642K	$1M+	SH

Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Redmile Group, LLC

SC 13G/A · Feb 17, 2026

9.9%

15.4M shares

SC 13G/A · Feb 5, 2026

7.1%

10.2M shares

BlackRock, Inc.

SC 13G/A · Jan 21, 2026

6.1%

8.9M shares

Satter Muneer A

SC 13D/A · Nov 22, 2025

7.2%

10.4M shares

SC 13G/A · Nov 5, 2025

10.1%

11.1M shares

The Vanguard Group

SC 13G · Oct 30, 2025

5.3%

5.8M shares

Logos Global Management LP

SC 13G/A · Aug 14, 2025

0.0%

0 shares

SC 13G/A · Aug 6, 2025

14.3%

15.7M shares

Point72 Asset Management, L.P.

SC 13G/A · May 15, 2025

0.1%

95K shares

The Vanguard Group

SC 13G/A · Apr 30, 2025

4.9%

5.4M shares

Logos Global Management LP

SC 13G · Apr 28, 2025

6.0%

6.6M shares

BCLS I Investco, LP

SC 13G/A · Feb 14, 2025

4.9%

5.2M shares

The Vanguard Group

SC 13G · Jan 31, 2025

5.2%

5.5M shares

SC 13G/A · Dec 6, 2024

13.1%

13.9M shares

SC 13G/A · Nov 15, 2024

4.9%

5.2M shares

Logos Global Management LP

SC 13G/A · Nov 14, 2024

2.7%

2.9M shares

Bain Capital Life Sciences Fund, L.P. 2

SC 13G/A · Nov 14, 2024

2.1%

2.2M shares

Biotechnology Value Fund, L.P.

SC 13G/A · Nov 14, 2024

4.5%

4.8M shares

T. ROWE PRICE ASSOCIATES, INC. 52-0556948

SC 13G/A · Nov 14, 2024

1.0%

1.0M shares

SC 13G/A · Nov 12, 2024

8.1%

8.6M shares

Adage Capital Management, L.P.

SC 13G/A · Nov 12, 2024

3.3%

3.5M shares

BlackRock, Inc.

SC 13G · Nov 8, 2024

7.2%

7.6M shares

BlackRock, Inc.

SC 13G · Oct 22, 2024

7.2%

7.6M shares

SC 13G · Apr 23, 2024

5.2%

4.7M shares

Venrock Healthcare Capital Partners II, L.P.

SC 13G/A · Feb 15, 2024

0.0%

0 shares

Citadel Advisors LLC

SC 13G/A · Feb 14, 2024

1.3%

6 shares

Redmile Group, LLC

SC 13G/A · Feb 14, 2024

9.9%

8.1M shares

Fairmount Funds Management LLC

SC 13G/A · Feb 14, 2024

0.4%

323K shares

Eventide Asset Management, LLC

SC 13G/A · Feb 14, 2024

0.0%

0 shares

Biotechnology Value Fund, L.P.

SC 13G/A · Feb 14, 2024

4.7%

3.7M shares

Logos Global Management LP

SC 13G/A · Feb 14, 2024

8.3%

6.9M shares

Bain Capital Life Sciences Fund, L.P. 2

SC 13G/A · Feb 13, 2024

10.0%

8.1M shares

Point72 Asset Management, L.P.

SC 13G · Feb 12, 2024

6.2%

4.9M shares

SC 13G · Jan 10, 2024

12.4%

9.7M shares

Federated Hermes, Inc.

SC 13G/A · Aug 8, 2023

4.4%

2.3M shares

Logos Global Management LP

SC 13G · Jun 22, 2023

5.8%

3.1M shares

Bain Capital Life Sciences Fund, L.P.

SC 13G/A · May 30, 2023

5.5%

2.9M shares

Citadel Advisors LLC

SC 13G · Feb 27, 2023

4.9%

6 shares

Muneer A. Satter

SC 13D/A · Feb 17, 2023

15.0%

7.7M shares

Redmile Group, LLC

SC 13G/A · Feb 14, 2023

9.9%

4.9M shares

Venrock Healthcare Capital Partners II, L.P.

SC 13G/A · Feb 14, 2023

10.0%

4.9M shares

Fairmount Funds Management LLC

SC 13G/A · Feb 14, 2023

7.7%

3.7M shares

Eventide Asset Management, LLC

SC 13G/A · Feb 14, 2023

7.6%

3.6M shares

Bain Capital Life Sciences Fund, L.P.

SC 13G/A · Feb 14, 2023

10.0%

4.9M shares

AllianceBernstein L.P. 13-4064930

SC 13G/A · Feb 14, 2023

0.0%

0 shares

Biotechnology Value Fund, L.P.

SC 13G/A · Feb 13, 2023

4.3%

2.0M shares

Pictet Asset Management SA The reporting person disclaim beneficial ownership of the shares reported, which are owned of record and beneficially by Pictet Asset Management SA.

SC 13G · Feb 3, 2023

2.6%

1.2M shares

Federated Hermes, Inc.

SC 13G/A · Feb 1, 2023

6.4%

3.1M shares

Redmile Group, LLC

SC 13G/A · Jul 18, 2022

9.9%

4.9M shares

Muneer A. Satter

SC 13D · Jul 18, 2022

10.4%

5.0M shares

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