XLO

Xilio Therapeutics, Inc.

Pharmaceutical PreparationsNasdaq<br>Emerging growth company

Total Trades

13

Buys

3

Sells

6

Largest Trade

N/A

Insiders

6

Institutional Funds

25

Inst. Value

$1M+

Activist Filings

29

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Brennan Kevin M.SVPEXERCISEN/A5KJan 5, 2026
Brennan Kevin M.SVPSELL$1K–$15K2K$0.64Jan 5, 2026
Frankenfield Christopher JamesCFOSELL$1K–$15K7K$0.64Jan 5, 2026
Frankenfield Christopher JamesCFOEXERCISEN/A19KJan 5, 2026
Shannon James SamuelDirectorBUY$15K–$50K70K$0.69Jun 18, 2025
Russo RenePRESIDENT AND CEOBUY$15K–$50K36K$0.68Jun 18, 2025
Frankenfield Christopher JamesCFOSELL$1K–$15K7K$0.98Jan 3, 2025
Frankenfield Christopher JamesCFOEXERCISEN/A19KJan 3, 2025
Brennan Kevin M.SVPSELL$1K–$15K2K$0.98Jan 3, 2025
Brennan Kevin M.SVPEXERCISEN/A5KJan 3, 2025
GILEAD SCIENCES, INC.10% OwnerBUY$100K–$500K485K$0.76Apr 3, 2024
Atlas Venture Fund XI, L.P.10% OwnerSELL<$1K1K$0.64Feb 9, 2024
Atlas Venture Fund XI, L.P.10% OwnerSELL$1K–$15K4K$0.85Jan 16, 2024
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Institutional Ownership

13F filings as of Dec 31, 2025 · 25 funds holding

Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

6.7%

4.7M shares

GILEAD SCIENCES, INC.

SC 13G/A · Feb 12, 2026

19.9%

14.5M shares

Coastlands Capital LP

SC 13G · Dec 11, 2025

10.0%

5.3M shares

Point72 Asset Management, L.P.

SC 13G/A · Nov 14, 2025

9.9%

8.0M shares

StemPoint Capital LP

SC 13G · Nov 14, 2025

7.2%

4.0M shares

GILEAD SCIENCES, INC.

SC 13G/A · Aug 14, 2025

19.9%

10.6M shares

9.9%

8.1M shares

Point72 Asset Management, L.P.

SC 13G · Jun 17, 2025

7.2%

4.0M shares

6.3%

3.5M shares

Rock Springs Capital Management LP

SC 13G/A · May 15, 2025

0.0%

0 shares

AbbVie Inc.

SC 13G · Feb 18, 2025

9.0%

4.3M shares

GILEAD SCIENCES INC

SC 13G/A · Dec 19, 2024

19.9%

9.1M shares

10.0%

4.6M shares

Atlas Venture Fund XI, L.P.

SC 13G/A · Nov 14, 2024

0.0%

0 shares

Rock Springs Capital Management LP

SC 13G/A · Nov 12, 2024

6.8%

3.0M shares

FMR LLC

SC 13G/A · Nov 12, 2024

3.2%

1.4M shares

GKCC, LLC

SC 13G · Sep 28, 2024

15.9%

7.0M shares

4.0%

1.5M shares

Gilead Sciences, Inc. 2

SC 13G · Apr 5, 2024

19.9%

7.3M shares

Rock Springs Capital Management LP

SC 13G/A · Apr 5, 2024

8.7%

3.0M shares

5.2%

1.4M shares

Merck & Co., Inc.

SC 13G · Apr 10, 2023

5.4%

1.5M shares

OCTAGON CAPITAL ADVISORS LP

SC 13G · Jan 25, 2023

8.8%

2.4M shares

Deerfield Mgmt, L.P.

SC 13G/A · Dec 29, 2022

0.0%

0 shares

RA Capital Management, L.P.

SC 13G/A · Nov 14, 2022

0.0%

0 shares

RA Capital Management, L.P.

SC 13G/A · Feb 14, 2022

7.3%

2.0M shares

4.9%

1.3M shares

Deerfield Mgmt, L.P.

SC 13G/A · Feb 11, 2022

3.7%

1.0M shares

5.4%

1.5M shares

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