UPB

Upstream Bio, Inc.

Pharmaceutical PreparationsNasdaq<br>Emerging growth company

Total Trades

Buys

Sells

Largest Trade

$1M+

Insiders

Institutional Funds

Inst. Value

$1M+

Activist Filings

Insider Trades

Insider	Title	Type	Value	Shares	Price	Date
Chimovits Erez	Director	BUY	$1M+	825K	$17.00	Oct 17, 2024
ORBIMED ADVISORS LLC	Director	BUY	$1M+	825K	$17.00	Oct 17, 2024
AI Upstream LLC	10% Owner	BUY	$1M+	1.2M	$17.00	Oct 17, 2024

🔓Seeing ranges? Sign in for exact trade values — free forever

13F filings as of Dec 31, 2025 · 89 funds holding

Fund	Shares	Value	Type
ORBIMED ADVISORS LLC	5.7M	$1M+	SH
Decheng Capital LLC	3.1M	$1M+	SH
NORGES BANK	2.9M	$1M+	SH
Enavate Sciences GP, LLC	2.5M	$1M+	SH
VANGUARD GROUP INC	2.1M	$1M+	SH
UBS Group AG	1.8M	$1M+	SH
Bain Capital Life Sciences Investors, LLC	1.3M	$1M+	SH
STATE STREET CORP	1.3M	$1M+	SH
VR Adviser, LLC	1.2M	$1M+	SH
Pictet Asset Management Holding SA	773K	$1M+	SH
GEODE CAPITAL MANAGEMENT, LLC	742K	$1M+	SH
Samsara BioCapital, LLC	736K	$1M+	SH
Siren, L.L.C.	588K	$1M+	SH
BARCLAYS PLC	524K	$1M+	SH
Nantahala Capital Management, LLC	495K	$1M+	SH
MARSHALL WACE, LLP	344K	$1M+	SH
GOLDMAN SACHS GROUP INC	333K	$1M+	SH
Alyeska Investment Group, L.P.	298K	$1M+	SH
JENNISON ASSOCIATES LLC	289K	$1M+	SH
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	285K	$1M+	SH