SION
Sionna Therapeutics, Inc.
Pharmaceutical PreparationsNasdaqNon-accelerated filer<br>Smaller reporting company<br>Emerging growth company
Total Trades
28
Buys
1
Sells
22
Largest Trade
$1M+
Insiders
8
Institutional Funds
71
Inst. Value
$1M+
Activist Filings
10
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Thompson Peter A. | Director | SELL | $1M+ | 31K | $44.58 | Feb 5, 2026 |
| ORBIMED ADVISORS LLC | Director | SELL | $1M+ | 31K | $44.58 | Feb 5, 2026 |
| TPG GP A, LLC | 10% Owner | SELL | $1M+ | 250K | $40.00 | Jan 26, 2026 |
| ORBIMED ADVISORS LLC | Director | SELL | $1M+ | 33K | $44.55 | Dec 30, 2025 |
| Thompson Peter A. | Director | SELL | $1M+ | 33K | $44.55 | Dec 30, 2025 |
| ORBIMED ADVISORS LLC | Director | SELL | $50K–$100K | 2K | $44.49 | Dec 20, 2025 |
| Thompson Peter A. | Director | SELL | $50K–$100K | 2K | $44.49 | Dec 20, 2025 |
| Fitzpatrick Jennifer | Chief Legal Officer | EXERCISE | $50K–$100K | 10K | $6.11 | Dec 9, 2025 |
| Fitzpatrick Jennifer | Chief Legal Officer | SELL | $100K–$500K | 10K | $40.52 | Dec 9, 2025 |
| ORBIMED ADVISORS LLC | Director | SELL | $1M+ | 108K | $44.55 | Nov 26, 2025 |
| Thompson Peter A. | Director | SELL | $1M+ | 108K | $44.55 | Nov 26, 2025 |
| RA CAPITAL MANAGEMENT, L.P. | Director | SELL | $1M+ | 30K | $39.61 | Nov 24, 2025 |
| RA CAPITAL MANAGEMENT, L.P. | Director | SELL | $1M+ | 136K | $40.34 | Nov 20, 2025 |
| RA CAPITAL MANAGEMENT, L.P. | Director | SELL | $1M+ | 374K | $39.51 | Oct 29, 2025 |
| Cloonan Michael | President & CEO | EXERCISE | $500K+ | 100K | $6.11 | Oct 22, 2025 |
| Cloonan Michael | President & CEO | SELL | $1M+ | 100K | $36.26 | Oct 22, 2025 |
| Booth Bruce | Director | SELL | $1M+ | 89K | $34.22 | Oct 21, 2025 |
| Booth Bruce | Director | SELL | $1M+ | 286K | $32.30 | Oct 21, 2025 |
| Booth Bruce | Director | SELL | $1M+ | 79K | $30.08 | Oct 1, 2025 |
| Cloonan Michael | President & CEO | SELL | $500K+ | 25K | $29.11 | Sep 30, 2025 |
| Cloonan Michael | President & CEO | EXERCISE | $100K–$500K | 25K | $6.11 | Sep 30, 2025 |
| Fitzpatrick Jennifer | Chief Legal Officer | SELL | $100K–$500K | 10K | $23.12 | Sep 5, 2025 |
| Fitzpatrick Jennifer | Chief Legal Officer | EXERCISE | $50K–$100K | 10K | $6.11 | Sep 5, 2025 |
| Ridloff Elena | CFO & Head of Corp… | SELL | $100K–$500K | 10K | $25.09 | Sep 3, 2025 |
| Cloonan Michael | President & CEO | EXERCISE | $100K–$500K | 25K | $6.11 | Aug 28, 2025 |
| Cloonan Michael | President & CEO | SELL | $500K+ | 25K | $24.97 | Aug 28, 2025 |
| Ridloff Elena | CFO & Head of Corp… | SELL | $500K+ | 23K | $25.70 | Aug 28, 2025 |
| TPG GP A, LLC | 10% Owner | BUY | $500K+ | 60K | $15.84 | Jul 1, 2025 |
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Institutional Ownership
13F filings as of Dec 31, 2025 · 71 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9.9M | $1M+ | SH |
| TPG GP A, LLC | 6.7M | $1M+ | SH |
| ORBIMED ADVISORS LLC | 3.6M | $1M+ | SH |
| VIKING GLOBAL INVESTORS LP | 3.2M | $1M+ | SH |
| Atlas Venture Life Science Advisors, LLC | 3.0M | $1M+ | SH |
| Enavate Sciences GP, LLC | 2.5M | $1M+ | SH |
| PERCEPTIVE ADVISORS LLC | 1.2M | $1M+ | SH |
| JENNISON ASSOCIATES LLC | 1.1M | $1M+ | SH |
| VANGUARD GROUP INC | 1.1M | $1M+ | SH |
| Aberdeen Group plc | 840K | $1M+ | SH |
| STATE STREET CORP | 693K | $1M+ | SH |
| EVENTIDE ASSET MANAGEMENT, LLC | 639K | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 332K | $1M+ | SH |
| Siren, L.L.C. | 300K | $1M+ | SH |
| Soleus Capital Management, L.P. | 269K | $1M+ | SH |
| Kalehua Capital Management LLC | 197K | $1M+ | SH |
| Alyeska Investment Group, L.P. | 136K | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 124K | $1M+ | SH |
| Artia Global Partners LP | 120K | $1M+ | SH |
| TD ASSET MANAGEMENT INC | 113K | $1M+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13D/A · Nov 7, 2025
22.6%
10.1M shares
SC 13D/A · Oct 21, 2025
5.4%
2.4M shares
SC 13G · Jul 30, 2025
5.0%
2.2M shares
SC 13G · Jun 16, 2025
5.0%
2.2M shares
SC 13D · Feb 19, 2025
15.2%
6.7M shares
SC 13D · Feb 18, 2025
6.5%
2.9M shares
SC 13D · Feb 18, 2025
23.7%
10.4M shares
SC 13D · Feb 18, 2025
5.6%
2.5M shares
SC 13G · Feb 14, 2025
6.7%
3.0M shares
SC 13D · Feb 13, 2025
8.4%
3.7M shares