PRME

Prime Medicine, Inc.

Biological Products, (No Diagnostic Substances)Nasdaq<br>Emerging growth company

Total Trades

Buys

Sells

Largest Trade

$1M+

Insiders

Institutional Funds

139

Inst. Value

$1M+

Activist Filings

Insider Trades

Insider	Title	Type	Value	Shares	Price	Date
NELSEN ROBERT	Director	BUY	$1M+	3.0M	$3.30	Aug 1, 2025
ARCH Venture Partners XII, LLC	10% Owner	BUY	$1M+	3.0M	$3.30	Aug 1, 2025
ARCH Venture Partners X, LLC	10% Owner	BUY	$1M+	3.0M	$3.30	Aug 1, 2025
Liu David R.	10% Owner	BUY	$50K–$100K	21K	$2.52	Jul 1, 2025
Liu David R.	10% Owner	BUY	$15K–$50K	21K	$2.16	Jun 23, 2025
Liu David R.	10% Owner	BUY	$15K–$50K	21K	$1.49	Jun 16, 2025
Liu David R.	10% Owner	BUY	$15K–$50K	21K	$1.60	Jun 12, 2025
Brudnick Richard	Chief Business Off…	BUY	$15K–$50K	20K	$1.19	May 22, 2025
LEE ANN L.	Chief Technical Of…	BUY	$100K–$500K	100K	$1.13	May 22, 2025
Reine Allan	CEO	BUY	$100K–$500K	125K	$1.18	May 22, 2025
NELSEN ROBERT	Director	BUY	$1M+	3.2M	$6.25	Feb 20, 2024
ARCH Venture Partners XII, LLC	10% Owner	BUY	$1M+	3.2M	$6.25	Feb 20, 2024
ARCH Venture Partners X, LLC	10% Owner	BUY	$1M+	3.2M	$6.25	Feb 20, 2024
GV 2019 GP, L.L.C.	10% Owner	SELL	$500K+	56K	$15.03	Jun 22, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$1M+	73K	$14.93	Jun 20, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$500K+	57K	$15.00	Jun 15, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$100K–$500K	32K	$14.73	Jun 13, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$100K–$500K	20K	$16.63	Jun 9, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$500K+	52K	$16.88	Jun 7, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$500K+	62K	$14.17	Jun 2, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$100K–$500K	29K	$13.70	May 31, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$100K–$500K	31K	$13.45	May 26, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$1M+	132K	$14.33	May 24, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$1M+	90K	$13.62	May 22, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$500K+	66K	$12.63	May 18, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$1M+	185K	$12.74	May 16, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$1M+	114K	$13.82	May 12, 2023
GV 2019 GP, L.L.C.	10% Owner	SELL	$1M+	422K	$14.09	May 10, 2023
GV 2019 GP, L.L.C.	10% Owner	BUY	$1M+	800K	$17.00	Oct 27, 2022
ARCH Venture Partners X, LLC	10% Owner	BUY	$1M+	800K	$17.00	Oct 27, 2022
NELSEN ROBERT	Director	BUY	$1M+	800K	$17.00	Oct 27, 2022
Cahill Thomas	Director	BUY	$1M+	400K	$17.00	Oct 27, 2022

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Institutional Ownership

13F filings as of Dec 31, 2025 · 139 funds holding

Fund	Shares	Value	Type
Alphabet Inc.	16.6M	$1M+	SH
VANGUARD GROUP INC	5.6M	$1M+	SH
ARK Investment Management LLC	5.4M	$1M+	SH
STATE STREET CORP	5.1M	$1M+	SH
Sumitomo Mitsui Trust Group, Inc.	3.2M	$1M+	SH
Amova Asset Management Americas, Inc.	3.2M	$1M+	SH
BALYASNY ASSET MANAGEMENT L.P.	3.1M	$1M+	SH
GEODE CAPITAL MANAGEMENT, LLC	2.3M	$1M+	SH
RENAISSANCE TECHNOLOGIES LLC	1.1M	$1M+	SH
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	937K	$1M+	SH
Greenwich Wealth Management LLC	740K	$1M+	SH
HRT FINANCIAL LP	655K	$1M+	SH
Point72 Asset Management, L.P.	551K	$1M+	SH
MOORE CAPITAL MANAGEMENT, LP	500K	$1M+	SH
AQR CAPITAL MANAGEMENT LLC	400K	$1M+	SH
HighTower Advisors, LLC	400K	$1M+	SH
BARCLAYS PLC	364K	$1M+	SH
Bollard Group LLC	361K	$1M+	SH
Verition Fund Management LLC	291K	$1M+	SH
PEAK6 LLC	247K	$500K+	SH (Call)