Lyra Therapeutics, Inc.
Total Trades
16
Buys
10
Sells
6
Largest Trade
$1M+
Insiders
7
Institutional Funds
17
Inst. Value
$100K–$500K
Activist Filings
36
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Cavalier Jason | CFO | SELL | $1K–$15K | 769 | $3.36 | Jan 8, 2026 |
| Palasis Maria | President & CEO | SELL | $1K–$15K | 2K | $3.36 | Jan 8, 2026 |
| PERCEPTIVE ADVISORS LLC | 10% Owner | SELL | $100K–$500K | 46K | $3.98 | Nov 13, 2025 |
| PERCEPTIVE ADVISORS LLC | 10% Owner | SELL | $100K–$500K | 70K | $4.89 | Nov 10, 2025 |
| Palasis Maria | President & CEO | SELL | $1K–$15K | 2K | $8.91 | Jul 15, 2025 |
| Cavalier Jason | CFO | SELL | $1K–$15K | 684 | $8.91 | Jul 15, 2025 |
| Waksal Harlan | Executive Chair | BUY | $50K–$100K | 25K | $2.96 | Nov 13, 2023 |
| NBVM GP, LLC | 10% Owner | BUY | $1M+ | 1.8M | $2.43 | Jun 2, 2023 |
| ANDERSON EDWARD T | Director | BUY | $1M+ | 1.8M | $2.43 | Jun 2, 2023 |
| PERCEPTIVE ADVISORS LLC | Director | BUY | $1M+ | 3.6M | $2.49 | Jun 2, 2023 |
| MERRIFIELD C ANN | Director | BUY | $15K–$50K | 4K | $5.05 | Jun 13, 2022 |
| MERRIFIELD C ANN | Director | BUY | $15K–$50K | 4K | $4.83 | May 17, 2022 |
| PERCEPTIVE ADVISORS LLC | Director | BUY | $1M+ | 5.9M | $4.22 | Apr 14, 2022 |
| NBVM GP, LLC | 10% Owner | BUY | $1M+ | 2.4M | $4.22 | Apr 14, 2022 |
| ANDERSON EDWARD T | Director | BUY | $1M+ | 2.5M | $4.22 | Apr 14, 2022 |
| Waksal Harlan | Executive Chair | BUY | $500K+ | 237K | $4.22 | Apr 13, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 17 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| Ikarian Capital, LLC | 21K | $50K–$100K | SH |
| DRW Securities, LLC | 17K | $50K–$100K | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 9K | $15K–$50K | SH |
| Artia Global Partners LP | 9K | $15K–$50K | SH |
| BlackRock, Inc. | 704 | $1K–$15K | SH |
| EverSource Wealth Advisors, LLC | 338 | $1K–$15K | SH |
| SBI Securities Co., Ltd. | 80 | <$1K | SH |
| JPMORGAN CHASE & CO | 27 | <$1K | SH |
| COMERICA BANK | 23 | <$1K | SH |
| Wilmington Savings Fund Society, FSB | 20 | <$1K | SH |
| BNP PARIBAS FINANCIAL MARKETS | 16 | <$1K | SH |
| Global Retirement Partners, LLC | 15 | <$1K | SH |
| CITIGROUP INC | 3 | <$1K | SH |
| IFP Advisors, Inc | 1 | <$1K | SH |
| UBS Group AG | 1 | <$1K | SH |
| MORGAN STANLEY | 1 | <$1K | SH |
| CWM, LLC | 1 | N/A | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13G · Jan 21, 2026
9.9%
175K shares
SC 13D/A · Nov 25, 2025
0.0%
0 shares
SC 13D/A · Nov 18, 2025
5.5%
98K shares
SC 13D/A · Nov 13, 2025
7.8%
139K shares
SC 13D/A · Nov 10, 2025
11.2%
185K shares
SC 13D/A · Aug 14, 2025
15.6%
256K shares
SC 13G/A · Feb 14, 2025
0.0%
0 shares
SC 13D/A · Dec 17, 2024
1.3B shares
Point72 Asset Management, L.P.
SC 13G/A · Nov 15, 2024
0.0%
0 shares
Venrock Healthcare Capital Partners II, L.P.
SC 13G/A · Nov 14, 2024
1.8%
1.2M shares
SC 13G/A · Nov 14, 2024
5.0%
3.3M shares
Nantahala Capital Management, LLC
SC 13G/A · Nov 14, 2024
1.1%
702K shares
SC 13G/A · Nov 14, 2024
0.0%
0 shares
SC 13D/A · Aug 15, 2024
1.3B shares
SC 13G/A · Feb 15, 2024
3.1%
1.6M shares
Venrock Healthcare Capital Partners II, L.P.
SC 13G/A · Feb 15, 2024
10.0%
5.6M shares
SC 13G/A · Feb 14, 2024
7.9%
6 shares
Nantahala Capital Management, LLC
SC 13G/A · Feb 14, 2024
8.9%
4.8M shares
SC 13D/A · Feb 14, 2024
1.3B shares
Point72 Asset Management, L.P.
SC 13G/A · Feb 14, 2024
5.7%
3.0M shares
SC 13G · Feb 13, 2024
5.7%
3.0M shares
Point72 Asset Management, L.P.
SC 13G · Nov 16, 2023
5.4%
3.0M shares
SC 13G · Aug 25, 2023
5.6%
2.8M shares
SC 13G · Jun 12, 2023
5.8%
6 shares
SC 13D/A · Jun 9, 2023
11.9%
5.9M shares
SC 13D/A · Jun 2, 2023
25.8%
12.8M shares
Nantahala Capital Management, LLC
SC 13G · Feb 14, 2023
7.0%
2.2M shares
Venrock Healthcare Capital Partners II, L.P.
SC 13G/A · Feb 14, 2023
10.0%
3.4M shares
SC 13G/A · Feb 14, 2023
6.8%
2.2M shares
SC 13G/A · Feb 13, 2023
2.3%
738K shares
SC 13G · Nov 8, 2022
8.7%
2.8M shares
SC 13D/A · Apr 22, 2022
12.8%
4.1M shares
Venrock Healthcare Capital Partners II, L.P.
SC 13G · Apr 22, 2022
10.0%
3.4M shares
SC 13D/A · Apr 14, 2022
24.8%
9.1M shares
SC 13G/A · Feb 14, 2022
3.0%
395K shares
ArrowMark Colorado Holdings, LLC
SC 13G/A · Feb 14, 2022
0.0%
0 shares