LEXICON PHARMACEUTICALS, INC.
Total Trades
20
Buys
19
Sells
0
Largest Trade
$1M+
Insiders
8
Institutional Funds
98
Inst. Value
$1M+
Activist Filings
16
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| DEBBANE RAYMOND | Director | BUY | $100K–$500K | 268K | $1.31 | Feb 18, 2026 |
| Invus Global Management, LLC | Director | BUY | $1M+ | 1.5M | $1.30 | Feb 4, 2026 |
| Invus Global Management, LLC | Director | GRANT | $1M+ | 22.8M | $2.33 | Feb 4, 2026 |
| COATS LONNEL | CEO | BUY | $50K–$100K | 90K | $1.05 | Nov 17, 2023 |
| Amouyal Philippe | Director | BUY | $100K–$500K | 200K | $1.01 | Nov 14, 2023 |
| COATS LONNEL | CEO | BUY | $1K–$15K | 10K | $1.01 | Nov 13, 2023 |
| DEBBANE RAYMOND | Director | BUY | $1M+ | 1.0M | $1.10 | Oct 12, 2023 |
| WADE JEFFREY L | President and CFO | BUY | $1K–$15K | 10K | $1.38 | Sep 14, 2023 |
| McDermott Wendy | VP, Human Resources | BUY | $1K–$15K | 6K | $1.84 | Aug 7, 2023 |
| COATS LONNEL | CEO | BUY | $15K–$50K | 10K | $2.16 | Jun 29, 2023 |
| McDermott Wendy | VP, Human Resources | BUY | $15K–$50K | 10K | $2.43 | Jun 27, 2023 |
| COATS LONNEL | CEO | BUY | $15K–$50K | 20K | $2.34 | Jun 26, 2023 |
| COATS LONNEL | CEO | BUY | $50K–$100K | 40K | $2.31 | Jun 22, 2023 |
| WADE JEFFREY L | President and CFO | BUY | $15K–$50K | 12K | $2.33 | Jun 20, 2023 |
| Artal International S.C.A. | Director | BUY | $1M+ | 27.8M | $2.60 | Jun 5, 2023 |
| Invus US Partners LLC | Director | BUY | $100K–$500K | 147K | $2.50 | Aug 9, 2022 |
| Artal International S.C.A. | Director | BUY | $1M+ | 2.4M | $2.50 | Aug 9, 2022 |
| Artal International S.C.A. | Director | BUY | $1M+ | 16.2M | $2.50 | Aug 1, 2022 |
| Invus US Partners LLC | Director | BUY | $1M+ | 983K | $2.50 | Aug 1, 2022 |
| DEBBANE RAYMOND | Director | BUY | $1M+ | 983K | $2.50 | Aug 1, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 98 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| Artal Group S.A. | 136.2M | $1M+ | SH |
| Siren, L.L.C. | 38.9M | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 2.1M | $1M+ | SH |
| CIBC Private Wealth Group LLC | 1.9M | $1M+ | SH |
| VANGUARD GROUP INC | 1.1M | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.1M | $1M+ | SH |
| GSA CAPITAL PARTNERS LLP | 996K | $1M+ | SH |
| JANE STREET GROUP, LLC | 961K | $1M+ | SH |
| Hennion & Walsh Asset Management, Inc. | 901K | $1M+ | SH |
| STATE STREET CORP | 885K | $1M+ | SH |
| MARSHALL WACE, LLP | 665K | $500K+ | SH |
| ACADIAN ASSET MANAGEMENT LLC | 640K | $500K+ | SH |
| Compagnie Lombard Odier SCmA | 410K | $100K–$500K | SH |
| Point72 Asset Management, L.P. | 284K | $100K–$500K | SH |
| OMERS ADMINISTRATION Corp | 274K | $100K–$500K | SH |
| RENAISSANCE TECHNOLOGIES LLC | 263K | $100K–$500K | SH |
| GROUP ONE TRADING LLC | 224K | $100K–$500K | SH |
| BARCLAYS PLC | 195K | $100K–$500K | SH |
| Ikarian Capital, LLC | 165K | $100K–$500K | SH |
| Headlands Technologies LLC | 136K | $100K–$500K | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
SC 13D/A · Feb 3, 2026
10.0%
42.8M shares
SC 13G/A · Jul 8, 2025
10.5%
38.1M shares
SC 13G/A · May 12, 2025
9.6%
34.5M shares
SC 13D/A · Dec 10, 2024
10.8%
38.9M shares
Biotechnology Value Fund, L.P.
SC 13G/A · Nov 14, 2024
0.0%
0 shares
SC 13G/A · Nov 12, 2024
13.8%
49.9M shares
SC 13D/A · Jul 29, 2024
10.8%
38.9M shares
SC 13G · Jul 10, 2024
10.7%
38.7M shares
SC 13D/A · May 14, 2024
10.8%
38.9M shares
SC 13D/A · Mar 14, 2024
15.8%
38.9M shares
Biotechnology Value Fund, L.P.
SC 13G/A · Feb 14, 2024
5.1%
12.6M shares
SC 13D/A · Jun 5, 2023
15.9%
38.9M shares
Biotechnology Value Fund, L.P.
SC 13G/A · Feb 13, 2023
4.6%
8.7M shares
SC 13D/A · Aug 9, 2022
20.6%
38.9M shares
SC 13D/A · Aug 1, 2022
21.2%
38.9M shares
Biotechnology Value Fund, L.P.
SC 13G/A · Feb 12, 2022
5.1%
7.6M shares