HOWL

Werewolf Therapeutics, Inc.

Pharmaceutical PreparationsNasdaq<br>Emerging growth company

Total Trades

41

Buys

2

Sells

39

Largest Trade

$1M+

Insiders

4

Institutional Funds

37

Inst. Value

$1M+

Activist Filings

27

Insider Trades

InsiderTitleTypeValueSharesPriceDate
EVNIN LUKEDirectorSELL$15K–$50K39K$0.54Jan 20, 2026
EVNIN LUKEDirectorSELL$50K–$100K111K$0.56Jan 15, 2026
EVNIN LUKEDirectorSELL$50K–$100K91K$0.59Jan 12, 2026
EVNIN LUKEDirectorSELL$15K–$50K71K$0.65Jan 7, 2026
EVNIN LUKEDirectorSELL$15K–$50K78K$0.62Jan 2, 2026
EVNIN LUKEDirectorSELL$100K–$500K291K$0.64Dec 29, 2025
EVNIN LUKEDirectorSELL$50K–$100K48K$1.08Dec 17, 2025
EVNIN LUKEDirectorSELL$50K–$100K83K$1.07Dec 12, 2025
EVNIN LUKEDirectorSELL$50K–$100K95K$1.00Dec 9, 2025
EVNIN LUKEDirectorSELL$100K–$500K128K$0.92Dec 4, 2025
MPM BioVentures 2014, L.P.InsiderSELL$100K–$500K200K$0.92Dec 4, 2025
GADICKE ANSBERTInsiderSELL$100K–$500K200K$0.92Dec 4, 2025
EVNIN LUKEDirectorSELL$50K–$100K91K$0.96Dec 1, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K142K$0.96Dec 1, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K142K$0.96Dec 1, 2025
EVNIN LUKEDirectorSELL$100K–$500K126K$0.92Nov 25, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K196K$0.92Nov 25, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K196K$0.92Nov 25, 2025
EVNIN LUKEDirectorSELL$50K–$100K103K$0.92Nov 20, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K160K$0.92Nov 20, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K160K$0.92Nov 20, 2025
EVNIN LUKEDirectorSELL$100K–$500K135K$0.96Nov 18, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K210K$0.96Nov 18, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K210K$0.96Nov 18, 2025
EVNIN LUKEDirectorSELL$100K–$500K137K$1.13Nov 13, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K214K$1.13Nov 13, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K214K$1.13Nov 13, 2025
EVNIN LUKEDirectorSELL$100K–$500K156K$1.22Nov 7, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K243K$1.22Nov 7, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K243K$1.22Nov 7, 2025
EVNIN LUKEDirectorSELL$100K–$500K189K$1.33Nov 4, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K295K$1.33Nov 4, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K295K$1.33Nov 4, 2025
EVNIN LUKEDirectorSELL$100K–$500K177K$1.62Oct 29, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$100K–$500K276K$1.62Oct 29, 2025
GADICKE ANSBERT10% OwnerSELL$100K–$500K276K$1.62Oct 29, 2025
RA CAPITAL MANAGEMENT, L.P.DirectorBUY$100K–$500K536K$0.91May 14, 2025
MPM BioVentures 2014, L.P.10% OwnerSELL$1K–$15K2K$1.05Apr 30, 2025
EVNIN LUKEDirectorSELL$1K–$15K2K$1.05Apr 30, 2025
GADICKE ANSBERT10% OwnerSELL$1K–$15K4K$1.05Apr 30, 2025
RA CAPITAL MANAGEMENT, L.P.DirectorBUY$1M+1.9M$2.21Jan 10, 2023
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Institutional Ownership

13F filings as of Dec 31, 2025 · 37 funds holding

FundShares
DC Funds, LP589K
RA CAPITAL MANAGEMENT, L.P.6.7M
MPM BioImpact LLC1.4M
RENAISSANCE TECHNOLOGIES LLC678K
SPHERA FUNDS MANAGEMENT LTD.627K
GEODE CAPITAL MANAGEMENT, LLC279K
Alyeska Investment Group, L.P.236K
VANGUARD GROUP INC180K
STATE STREET CORP119K
JANE STREET GROUP, LLC98K
Vontobel Holding Ltd.60K
EDGEWOOD MANAGEMENT LLC50K
GOLDMAN SACHS GROUP INC34K
SIMPLEX TRADING, LLC24K
UBS Group AG20K
CERTUITY, LLC15K
Delta Investment Management, LLC15K
Point72 Asset Management, L.P.14K
BARCLAYS PLC13K
Larson Financial Group LLC13K

Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

Longwood Fund III GP, LLC

SC 13G/A · Feb 11, 2026

3.5%

1.7M shares

MPM BioVentures 2014, L.P.

SC 13D/A · Jan 16, 2026

3.0%

1.5M shares

MPM BioVentures 2014, L.P.

SC 13D/A · Dec 29, 2025

3.6%

1.7M shares

MPM BioVentures 2014, L.P.

SC 13D/A · Dec 4, 2025

4.3%

2.1M shares

MPM BioVentures 2014, L.P.

SC 13D/A · Nov 18, 2025

4.9%

2.4M shares

RA Capital Management, L.P.

SC 13D/A · Nov 6, 2025

13.8%

6.7M shares

MPM BioVentures 2014, L.P.

SC 13D/A · Nov 4, 2025

5.8%

2.7M shares

PFM Health Sciences, LP

SC 13G/A · Aug 14, 2025

0.9%

401K shares

RA Capital Management, L.P.

SC 13D/A · May 14, 2025

15.0%

6.7M shares

PFM Health Sciences, LP

SC 13G/A · Feb 14, 2025

6.5%

2.9M shares

PFM Health Sciences, LP

SC 13G/A · Nov 14, 2024

7.8%

6 shares

BANK OF AMERICA CORP /DE/ 56-0906609

SC 13G/A · Nov 14, 2024

4.9%

2.2M shares

Rubric Capital Management LP

SC 13G/A · Nov 13, 2024

3.0%

1.3M shares

Adage Capital Management, L.P.

SC 13G/A · Nov 12, 2024

4.6%

2.0M shares

RA Capital Management, L.P.

SC 13D/A · May 7, 2024

14.2%

6.2M shares

RA Capital Management, L.P.

SC 13D/A · Feb 14, 2024

15.2%

6.2M shares

PFM Health Sciences, LP

SC 13G/A · Feb 14, 2024

9.6%

6 shares

5.8%

2.1M shares

Rubric Capital Management LP

SC 13G/A · Feb 12, 2024

5.3%

1.9M shares

Adage Capital Partners, L.P.

SC 13G · Dec 21, 2023

8.4%

3.0M shares

Rubric Capital Management LP

SC 13G · Feb 10, 2023

6.0%

1.8M shares

PFM Health Sciences, LP

SC 13G · Jan 17, 2023

5.3%

6 shares

PFM Health Sciences, LP

SC 13G/A · Jan 17, 2023

4.2%

6 shares

RA Capital Management, L.P.

SC 13D/A · Jan 10, 2023

18.0%

6.2M shares

RA Capital Management, L.P.

SC 13D/A · Aug 12, 2022

14.6%

4.3M shares

PFM Health Sciences, LP

SC 13G · May 2, 2022

5.5%

6 shares

Deerfield Mgmt, L.P.

SC 13G/A · Feb 11, 2022

3.5%

958K shares

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