Design Therapeutics, Inc.
Total Trades
11
Buys
10
Sells
1
Largest Trade
$1M+
Insiders
9
Institutional Funds
77
Inst. Value
$1M+
Activist Filings
21
Insider Trades
| Insider | Title | Type | Value | Shares | Price | Date |
|---|---|---|---|---|---|---|
| Schmid John P. | Director | BUY | $50K–$100K | 27K | $3.70 | Mar 25, 2024 |
| Berger Heather A. | Director | BUY | $1K–$15K | 1K | $3.74 | Mar 25, 2024 |
| LAPPE RODNEY W | Director | BUY | $15K–$50K | 21K | $2.35 | Oct 2, 2023 |
| Prasad Deepa | Director | BUY | $15K–$50K | 12K | $2.31 | Aug 30, 2023 |
| William Arsani | Director | BUY | $1M+ | 2.2M | $2.40 | Aug 30, 2023 |
| Siffert Joao MD | President and CEO | BUY | $50K–$100K | 7K | $8.39 | Dec 21, 2022 |
| George Simeon | Director | BUY | $1M+ | 900K | $8.42 | Dec 20, 2022 |
| SR One Capital Fund I Aggregator LP | 10% Owner | BUY | $1M+ | 900K | $8.42 | Dec 20, 2022 |
| LAPPE RODNEY W | Director | BUY | $100K–$500K | 15K | $7.96 | Dec 12, 2022 |
| William Arsani | Director | BUY | $100K–$500K | 25K | $18.99 | Mar 22, 2022 |
| Xu Stella | Director | SELL | $1M+ | 591K | $19.07 | Mar 22, 2022 |
Institutional Ownership
13F filings as of Dec 31, 2025 · 77 funds holding
| Fund | Shares | Value | Type |
|---|---|---|---|
| SR ONE CAPITAL MANAGEMENT, LP | 6.5M | $1M+ | SH |
| Point72 Asset Management, L.P. | 5.4M | $1M+ | SH |
| Logos Global Management LP | 2.5M | $1M+ | SH |
| Vivo Capital, LLC | 1.6M | $1M+ | SH |
| Almitas Capital LLC | 1.5M | $1M+ | SH |
| RA CAPITAL MANAGEMENT, L.P. | 1.5M | $1M+ | SH |
| STATE STREET CORP | 648K | $1M+ | SH |
| ACADIAN ASSET MANAGEMENT LLC | 613K | $1M+ | SH |
| GEODE CAPITAL MANAGEMENT, LLC | 590K | $1M+ | SH |
| Frazier Life Sciences Management, L.P. | 521K | $1M+ | SH |
| RENAISSANCE TECHNOLOGIES LLC | 287K | $1M+ | SH |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 237K | $1M+ | SH |
| DIMENSIONAL FUND ADVISORS LP | 226K | $1M+ | SH |
| GOLDMAN SACHS GROUP INC | 211K | $1M+ | SH |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 195K | $1M+ | SH |
| VANGUARD GROUP INC | 184K | $1M+ | SH |
| RAYMOND JAMES FINANCIAL INC | 110K | $1M+ | SH |
| MORGAN STANLEY | 101K | $500K+ | SH |
| BNP PARIBAS FINANCIAL MARKETS | 95K | $500K+ | SH |
| BARCLAYS PLC | 87K | $500K+ | SH |
Activist & 5%+ Owners
SC 13D/13G filings — investors holding 5%+ of outstanding shares
Point72 Asset Management, L.P.
SC 13G/A · Feb 17, 2026
9.4%
5.4M shares
SC 13D/A · Nov 18, 2025
4.4%
2.5M shares
SC 13D/A · Nov 12, 2025
5.7%
3.2M shares
Point72 Asset Management, L.P.
SC 13G · Aug 28, 2025
5.2%
2.9M shares
Star Irrevocable Trust #1 dated April 22, 2019
SC 13G/A · Feb 7, 2025
6.9%
3.8M shares
Light Irrevocable Trust #1 dated April 22, 2019
SC 13G/A · Feb 7, 2025
6.9%
3.8M shares
SC 13D/A · Aug 13, 2024
7.4%
4.2M shares
SC 13G/A · Feb 14, 2024
3.2%
6 shares
Cormorant Global Healthcare Master Fund, LP
SC 13G/A · Feb 14, 2024
0.0%
0 shares
STATE STREET CORPORATION I.R.S. IDENTIFICATION NO. OF THE ABOVE PERSON 04-2456637
SC 13G/A · Jan 23, 2024
1.2%
0 shares
SC 13G/A · Nov 14, 2023
0.0%
0 shares
SC 13G/A · Sep 7, 2023
4.3%
2.4M shares
SC 13G · Apr 3, 2023
4.6%
6 shares
Cormorant Global Healthcare Master Fund, LP
SC 13G/A · Feb 14, 2023
3.1%
1.7M shares
SC 13G/A · Feb 14, 2023
4.4%
6 shares
SC 13G · Feb 3, 2023
6.3%
3.5M shares
SR One Capital Fund I Aggregator, LP
SC 13D/A · Dec 22, 2022
11.7%
6.5M shares
SC 13G · Dec 22, 2022
4.4%
6 shares
SC 13G · Oct 13, 2022
5.3%
3.0M shares
SC 13D · Mar 31, 2022
5.0%
2.8M shares
Cormorant Global Healthcare Master Fund, LP
SC 13G/A · Feb 14, 2022
3.5%
2.0M shares