ANVS

Annovis Bio, Inc.

Pharmaceutical PreparationsNYSE<br>Emerging growth company

Total Trades

6

Buys

6

Sells

0

Largest Trade

$1M+

Insiders

2

Institutional Funds

44

Inst. Value

$1M+

Activist Filings

4

Insider Trades

InsiderTitleTypeValueSharesPriceDate
Hoffman Michael BDirectorBUY$100K–$500K45K$4.31Dec 9, 2025
Hoffman Michael BDirectorBUY$100K–$500K39K$4.08Nov 25, 2025
Hoffman Michael BDirectorBUY$50K–$100K20K$3.50Nov 22, 2025
Hoffman Michael BDirectorBUY$15K–$50K15K$2.11Nov 18, 2025
Maccecchini Maria-LuisaPresident & CEOBUY$100K–$500K98K$2.05Nov 12, 2025
Hoffman Michael BDirectorBUY$1M+976K$2.05Nov 12, 2025
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Institutional Ownership

13F filings as of Dec 31, 2025 · 44 funds holding

FundShares
JANE STREET GROUP, LLC198K
GEODE CAPITAL MANAGEMENT, LLC184K
D.A. DAVIDSON & CO.161K
BlackRock, Inc.140K
MARSHALL WACE, LLP132K
VANGUARD GROUP INC132K
Merit Financial Group, LLC81K
STATE STREET CORP74K
GROUP ONE TRADING LLC69K
OMERS ADMINISTRATION Corp62K
Greenwich Wealth Management LLC42K
Wescott Financial Advisory Group, LLC42K
FIRST NATIONAL TRUST CO40K
Sherry Group, Inc.27K
Virtu Financial LLC26K
Dakota Wealth Management26K
Sterling Investment Advisors, Ltd.23K
NewEdge Advisors, LLC21K
Wealthspire Advisors, LLC20K
GILL CAPITAL PARTNERS, LLC19K

Activist & 5%+ Owners

SC 13D/13G filings — investors holding 5%+ of outstanding shares

CVI Investments, Inc.

SC 13G/A · May 12, 2025

4.9%

1.0M shares

CVI Investments, Inc.

SC 13G · Feb 10, 2025

5.1%

1.0M shares

27-4413262

SC 13G/A · Nov 28, 2023

4.2%

435K shares

27-4413262

SC 13G · Nov 8, 2023

5.4%

549K shares

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